Results 121 to 130 of about 3,753,786 (301)

Numerical Optimization for Tensor Disentanglement

open access: yesCoRR
Tensor networks provide compact and scalable representations of high-dimensional data, enabling efficient computation in fields such as quantum physics, numerical partial differential equations (PDEs), and machine learning. This paper focuses on tensor disentangling, the task of identifying transformations that reduce bond dimensions by exploiting ...
Julia Wei   +4 more
openaire   +2 more sources

Extracellular matrix remodeling and immune reprogramming drive residual tumor progression of liver cancer after incomplete microwave ablation

open access: yesMolecular Oncology, EarlyView.
Incomplete microwave ablation (iMWA) of liver cancer triggers a biphasic progression in residual tumors. At Day 3, the microenvironment is characterized by acute inflammatory responses and extracellular matrix (ECM) remodeling. By Day 14, a profound shift occurs toward oncogenic signal transduction and immunosuppression, marked by macrophage ...
Yu Liu   +9 more
wiley   +1 more source

The Scythe Statistical Library: An Open Source C++ Library for Statistical Computation

open access: yesJournal of Statistical Software, 2011
The Scythe Statistical Library is an open source C++ library for statistical computation. It includes a suite of matrix manipulation functions, a suite of pseudo-random number generators, and a suite of numerical optimization routines.
Daniel Pemstein   +2 more
doaj  

Influence of Radial Pressure Gradient on Secondary Flows: Numerical Study and Design Optimization for High-Speed Annular Sector Cascades

open access: yesInternational Journal of Turbomachinery, Propulsion and Power
Secondary flow phenomena have a significant influence on the generation of losses and the propagation of coolant on the turbine end walls. The majority of film cooling studies are carried out on linear rather than annular cascades due to the structural ...
Moritz Klappenberger   +3 more
doaj   +1 more source

SPHINX31 acts as a SRPK1 inhibitor targeting the ATR/DNA‐PKcs/CHK1 replicative checkpoint to inhibit cell growth in non‐small cell lung cancer

open access: yesMolecular Oncology, EarlyView.
The kinase SRPK1 directly interacts with the protein TOPBP1 and regulates the pre‐mRNA splicing of WIZ thereby contributing to the activation of the ATR/CHK1 replicative checkpoint in response to replicative stress. This allows cancer cells' genomic stability and survival.
Amani Shreim   +17 more
wiley   +1 more source

Automated FRAP microscopy for high‐throughput analysis of protein dynamics in chromatin organization and transcription

open access: yesFEBS Open Bio, EarlyView.
RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz   +6 more
wiley   +1 more source

Stress-constrained topology optimization using the constrained natural element method [PDF]

open access: yes
This paper presents a topology optimization framework to achieve volume minimization with Crossland fatigue constraints under proportional loading using the Constrained Natural Element Method.
CHEN, Yanda   +4 more
core   +1 more source

FOCUS-HTS: a new stellarator coil design code for three-dimensional high-temperature superconducting magnets

open access: yesNuclear Fusion
Stellarators mainly utilize magnetic fields from external coils to confine the plasma, enabling steady-state operation while avoiding instabilities like disruptions raised from plasma currents.
Xianyi Nie   +5 more
doaj   +1 more source

Raman‐based label‐free microscopic analysis of the pancreas in living zebrafish larvae

open access: yesFEBS Open Bio, EarlyView.
Forward stimulated Raman scattering (F‐SRS) and epi coherent anti‐Stokes Raman scattering (E‐CARS) allow label‐free discrimination of distinct subcellular structures in the pancreas of living zebrafish larvae. Given the straightforward applicability, we anticipate broad implementation of Raman microscopy in other organs and across various biomedical ...
Noura Faraj   +3 more
wiley   +1 more source

Short Course on Optimization Technology and Applications in High Frequency and Microwave Circuit Design

open access: yes, 1994
Course notes and advertisement for a Short Course given at the Department of Electromagnetic Theory and Engineering, Duisburg University, Duisburg, Germany. The course was delivered by John W. Bandler and S.H. Chen on October 4 and 5, 1994.
Bandler, John W.   +2 more
core   +1 more source

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