Results 61 to 70 of about 922,998 (286)

Can math beat gamers in Quantum Moves?

, 2017
In a recent work on quantum state preparation, S{\o}rensen and colleagues explore the possibility of using video games to help design quantum control protocols. The authors present a game called "Quantum Moves" in which gamers have to move an atom from A
Sels, Dries
core   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

FEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe, Tanmay Kumar Mohanty, Rashna Bhandari, Dorothea Fiedler   +3 more
wiley   +1 more source

Function‐driven design of a surrogate interleukin‐2 receptor ligand

FEBS Letters, EarlyView.
Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang, Zelin Cheng, Teng Li, Fulian Wang, Liangminghui Zhang, Xiuxiu He, Lili Liu, Wei Wang, Aibin Liang, Guang Yang   +9 more
wiley   +1 more source

A new continuous optimization method of standardized cubic permanent magnets for stellarators

Nuclear Fusion
Stellarator configurations can be realized using permanent magnets in combination with tokamak-like planar coils. From the perspective of engineering feasibility and cost-effectiveness, using standardized cubic permanent magnets with a finite number of ...
Xiangyu Zhang, Dehong Chen, Guosheng Xu, Zhiyuan Lu, Caoxiang Zhu, Liang Chen, Minyou Ye, Baonian Wan   +7 more
doaj   +1 more source

Time after time – circadian clocks through the lens of oscillator theory

FEBS Letters, EarlyView.
Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo, Carolin Ector, Hanspeter Herzel   +2 more
wiley   +1 more source

Enhancing C2 and C3 coherency resolutions through optimizing semblance-based functions [PDF]

Geofísica Internacional, 2007
Apparent dips from 3-D reflectors are calculated by maximizing the semblance-based coherency (C2) by numerical optimization techniques. This maximization was done by means of searching through a tessellation of the apparent dips domain, and by ...
J.O. Campos-Enriquez, F. Reyes-Ramos
doaj  

Extremal Optimization of Graph Partitioning at the Percolation Threshold

, 1999
The benefits of a recently proposed method to approximate hard optimization problems are demonstrated on the graph partitioning problem. The performance of this new method, called Extremal Optimization, is compared to Simulated Annealing in extensive ...
Balberg I, Banavar J R, Boettcher S, Boettcher S, Cerny V, Cheeseman P, Erdös P, For those issues see, Fu Y T, Garey M R, Gould S J, H Frauenfelder, Houdayer J, Janson S, Johnson D S, Kirkpatrick S, Mezard M, Mezard M, Sorkin G B, Stauffer D, Stefan Boettcher, Toulouse G, Wong K Y M, Wong K Y M, Wong K Y M   +24 more
core   +1 more source

Numerical Inductor Optimization

Transactions of the Magnetics Society of Japan, 2002
This paper shows a method for the numerical quality factor optimization of a high frequency inductor based on a genetic algorithm. This is pointed out by an example of a trench-type or I-inductor. A comparison between different design approaches will show the advantages of themselves.
Axel Vonder Weth, J. Aktaa
openaire   +2 more sources

In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS

FEBS Letters, EarlyView.
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka, Yuxi Liu, Stefano Maggi, Debnath Ghosal, Jue Wang, Prashant P. Damke, Stephen D. Carter, Wei Zhao, Sukhithasri Vijayrajratnam, Joseph P. Vogel, Carrie L. Shaffer, Grant J. Jensen   +11 more
wiley   +1 more source

Sharp interface limit for a phase field model in structural optimization

, 2016
We formulate a general shape and topology optimization problem in structural optimization by using a phase field approach. This problem is considered in view of well-posedness and we derive optimality conditions.
Christoph Rupprecht, Claudia Hecht, Delfour M., Garcke H., Harald Garcke, Karchevsky A., Luise Blank, Modica L.   +7 more
core   +1 more source