Results 31 to 40 of about 16,000,085 (252)

Remarks on the quenching estimate for a nonlocal diffusion problem with a reaction term

Journal of Numerical Analysis and Approximation Theory, 2012
In this paper, we address the following initial value problem\[\begin{array}{ll}\hbox{\(u_t=\int_{\Omega}J(x-y)(u(y, t)-u(x, t)){\rm d}y+f(u(x, t))\quad \mbox{in}\quad \overline{\Omega}\times(0,T)\),} \\\hbox{\(u(x,0)=u_{0}(x)\geq 0\quad \mbox{in}\quad ...
Halima Nachid
doaj   +2 more sources

Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics

FEBS Letters, EarlyView.
Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt, Ana‐Maria Sandru, Georg Vucak, Sebastian Didusch, Biljana Riemelmoser, Karin Ehrenreiter, Markus Hartl, Lukas A. Huber, Manuela Baccarini   +8 more
wiley   +1 more source

Thermal analysis using induction and concentrated solar radiation for the heating of metals

Results in Engineering, 2022
It is described the thermal analysis of a cylindrical workpiece involving the coupling of two heat sources. Induction heating was applied, which generated Eddy currents that circulated through the workpiece and heated the material surface.
Armando Rojas-Morín, Yolanda Flores-Salgado, Omar Alvarez-Brito, Alejandro Jaramillo-Mora, Arturo Barba-Pingarrón   +4 more
doaj   +1 more source

Autophagy and mitophagy in pancreatic β‐cell homeostasis and their involvement in diabetes pathophysiology

FEBS Letters, EarlyView.
This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee, Mingming Tong, Anna L. Gloyn   +2 more
wiley   +1 more source

Simulation Model for the Laminar Plasma Jet Surface Quenching of the Rail Steel

工程科学与技术, 2021
Surface quenching of the rail steel using the laminar plasma jet can increase its service life, but the treatment parameters can only be determined by the experimental methods currently, which is time-consuming and laborious.
Deping YU, Bin ZHANG, Wenjie SONG, Da GUO, Keming PENG   +4 more
doaj  

Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network

FEBS Letters, EarlyView.
Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley   +1 more source

A new optimization procedure for the accurate characterization of thermal phase transformation curves based on controlled quenching experiments

MATEC Web of Conferences, 2016
Precise hardness and phase content prediction for quenched steel with the finite element method requires optimal material data, which is usually obtained from measured continuous cooling transformation (CCT) diagrams. However, most software packages that
Peterli Maurice, Truong Minh-Trung, Manopulo Niko, Hora Pavel   +3 more
doaj   +1 more source

Study on induction hardening performance of 34CrNi3MoA steel crankshaft

Frontiers in Materials, 2023
The evolution of the temperature field, microstructure field, and residual stress field of a 34CrNi3MoA steel marine diesel engine crankshaft during medium-frequency induction hardening was studied based on an electromagnetic-thermal-transformation ...
Xiaona Shi, Chenghao Lv, Guochao Li, Kelong Wang, Jianzhi Chen, Jie Tang   +5 more
doaj   +1 more source

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

Molecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla, Christopher Dirks, Caroline Eiden, Sonja K. Fesenmayer, Femke M. Hormann, Yolande Klootsema, Ingrid Lilienthal, Si Min Zhang, Nikolas Herold, Sean G. Rudd   +9 more
wiley   +1 more source

Numerical analysis of time-dependent Boussinesq models [PDF]

, 1990
In this paper we analyse numerical models for time-dependent Boussinesq equations. These equations arise when so-called Boussinesq terms are introduced into the shallow water equations.
J. Mooiman, Wubs, F.W.,, Houwen, Piet, Mooiman, J., F. W. Wubs, Houwen, P.J. (Piet) van der, Wubs, F.W., Houwen, P.J. van der,, Mooiman, J.,, Houwen, P.J. van der, Wubs, Fred, P. J. van der Houwen, Wubs, F.W.; id_orcid, Wubs, F.W. (Fred)   +13 more
core   +2 more sources