Results 61 to 70 of about 1,681,939 (273)

Numerical simulation of spacecraft charging phenomena [PDF]

open access: yes, 1977
A numerical simulation program is being constructed having the following features: (1) infinite circular cylindrical geometry with angle-dependence, (2) inclusion of incident particles, photoelectrons, secondary electrons, backscattered electrons, any ...
Laframboise, J. G., Prokopenko, S. M. L.
core   +1 more source

Numerical simulation with light Wilson-quarks

open access: yes, 2003
The computational cost of numerical simulations of QCD with light dynamical Wilson-quarks is estimated by determining the autocorrelation of various quantities.
Deutsches Elektronen-Synchrotron (DESY), Hamburg (Germany)   +1 more
core   +1 more source

An advanced meshless method for time fractional diffusion equation [PDF]

open access: yes, 2011
Recently, because of the new developments in sustainable engineering and renewable energy, which are usually governed by a series of fractional partial differential equations (FPDEs), the numerical modelling and simulation for fractional calculus are ...
Gu Y. T.   +7 more
core   +2 more sources

Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions

open access: yesFEBS Letters, EarlyView.
We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva   +10 more
wiley   +1 more source

Modeling hepatic fibrosis in TP53 knockout iPSC‐derived human liver organoids

open access: yesMolecular Oncology, EarlyView.
This study developed iPSC‐derived human liver organoids with TP53 gene knockout to model human liver fibrosis. These organoids showed elevated myofibroblast activation, early disease markers, and advanced fibrotic hallmarks. The use of profibrotic differentiation medium further amplified the fibrotic signature seen in the organoids.
Mustafa Karabicici   +8 more
wiley   +1 more source

Process Chain for Numerical Simulation of IMLS [PDF]

open access: yes, 2007
Additive layer manufacturing methods imply, among other advantages, extensive flexibility concerning their ability to realize mass customization. Despite various efforts towards process enhancement, numerous deficiencies concerning part distortion or ...
Branner, G., Strasser, G., Zaeh, M. F.
core   +1 more source

A synthetic benzoxazine dimer derivative targets c‐Myc to inhibit colorectal cancer progression

open access: yesMolecular Oncology, EarlyView.
Benzoxazine dimer derivatives bind to the bHLH‐LZ region of c‐Myc, disrupting c‐Myc/MAX complexes, which are evaluated from SAR analysis. This increases ubiquitination and reduces cellular c‐Myc. Impairing DNA repair mechanisms is shown through proteomic analysis.
Nicharat Sriratanasak   +8 more
wiley   +1 more source

Numerical simulation of flow over a rough bed [PDF]

open access: yes, 2004
This paper presents results of a direct numerical simulation (DNS) of turbulent flow over the rough bed of an open channel. We consider a hexagonal arrangement of spheres on the channel bed.
G. Salton   +4 more
core   +8 more sources

Aggressive prostate cancer is associated with pericyte dysfunction

open access: yesMolecular Oncology, EarlyView.
Tumor‐produced TGF‐β drives pericyte dysfunction in prostate cancer. This dysfunction is characterized by downregulation of some canonical pericyte markers (i.e., DES, CSPG4, and ACTA2) while maintaining the expression of others (i.e., PDGFRB, NOTCH3, and RGS5).
Anabel Martinez‐Romero   +11 more
wiley   +1 more source

Radiative cooling in numerical astrophysics: the need for adaptive mesh refinement

open access: yes, 2010
Energy loss through optically thin radiative cooling plays an important part in the evolution of astrophysical gas dynamics and should therefore be considered a necessary element in any numerical simulation. Although the addition of this physical process
Keppens, Rony, van Marle, Allard Jan
core   +1 more source

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