Numerical solution for MHD peristaltic transport in an inclined nanofluid symmetric channel with porous medium. [PDF]
Abd-Alla AM, Thabet EN, Bayones FS.
europepmc +1 more source
Tau acetylation at K331 has limited impact on tau pathology in vivo
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto +3 more
wiley +1 more source
Numerical solution of fractional boundary value problem with caputo-fabrizio and its fractional integral. [PDF]
Moumen Bekkouche M +2 more
europepmc +1 more source
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
Numerical solution of magnetohydrodynamics effects on a generalised power law fluid model of blood flow through a bifurcated artery with an overlapping shaped stenosis. [PDF]
Zain NM, Ismail Z.
europepmc +1 more source
This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel +13 more
wiley +1 more source
The paper describes a two-dimensional model of bioaerosol transport from a non-stationary source of admixture in the atmospheric boundary layer at the local level (the linear sizes of the studied area up to 40–50 km) taking into account the roughness and
K.G. Shvarts +4 more
doaj
Orthonormal piecewise Vieta-Lucas functions for the numerical solution of the one- and two-dimensional piecewise fractional Galilei invariant advection-diffusion equations. [PDF]
Heydari MH, Razzaghi M, Baleanu D.
europepmc +1 more source
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source
Numerical solution for circular tunnel excavated in strain-softening rock masses considering damaged zone. [PDF]
Li J, Shen C, He X, Zheng X, Yuan J.
europepmc +1 more source

