Results 201 to 210 of about 246,955 (263)

Leonurine Ameliorates Doxorubicin‐Induced Cardiotoxicity via STING/NF‐κB/NLRP3 Inflammasome Signaling Pathway

Advanced Science, EarlyView.
ABSTRACT Doxorubicin‐induced cardiomyopathy (DIC) remains a dose‐limiting clinical challenge. This study reveals that cardiac vascular endothelial cells (CVECs) act as initial sensors of doxorubicin cardiotoxicity: circulating doxorubicin activates the cGAS‑STING pathway in CVECs, triggering NLRP3 inflammasome‑mediated pyroptosis and release of ...
Wang Jun, Chen Xiaoyang, Xu Jianglin, Yang Zhi, Tao Meijiao, He Jiale, Zhao Jiangfeng, Hei Xuanding, Xu Xuegong, Wang Wei, Li Chun   +10 more
wiley   +1 more source

Stem Cell Differentiation Disperses Transcriptional Clusters via a Conserved Surface‐Condensate Trajectory

Advanced Science, EarlyView.
Stem cell differentiation follows a conserved surface condensate trajectory: H3K27ac super enhancers nucleate large RNA polymerase II clusters that grow and unfold before transcriptional activity disperses them. This work reveals how biophysical forces at enhancer surfaces dynamically build and dismantle stem cell transcription hubs, reshaping cell ...
Tim Klingberg, Irina Wachter, Agnieszka Pancholi, Matthias Akyel, Yomna Gohar, Priya Kumar, Ana Miguel Fernandes, Yuzhi Bao, Alica Schmidt‐Heydt, Marcel Piepers, Alicia Günthel, Marcel Sobucki, Elisa Kämmer, Süheyla Eroğlu‐Kayıkçı, Stephan Allgeier, Sylvia Erhardt, Vasily Zaburdaev, Carmelo Ferrai, Lennart Hilbert   +18 more
wiley   +1 more source

What AI Cannot Teach: An Epistemological Reconceptualisation of the Nurse Educator Role Based on an Analysis of Carper's Ways of Knowing. [PDF]

Nurs Inq
Sezer E.
europepmc   +1 more source

Structural and cultural barriers to patient education from the perspective of Iranian nurses: a qualitative study. [PDF]

BMC Nurs
Yaghmaei S, Kahrizi NR, Ranjipour Z, Gomarverdi S, Arasteh FT, Mosivand Z, Ghahremani R.   +6 more
europepmc   +1 more source

Nurse-led caregiver training interventions in post-stroke rehabilitation: a systematic review and meta-analysis of functional and psychosocial outcomes. [PDF]

Front Public Health
Gao S, Dong L, Li X.
europepmc   +1 more source

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Nursing theory in nursing education: An educational imperative

Journal of Professional Nursing, 1992
Nursing has accepted theory as basic to its practice; however, the use and development of nursing theory is constrained by the approach used in nursing education. It is not appropriate or sufficient to isolate theory in one course. Moreover, confining nursing theory courses to graduate curricula, which is the custom in many schools of nursing, suggests
L R, Lutjens, M L, Horan
openaire   +2 more sources

Transcultural nursing and nurse education

British Journal of Nursing, 1994
This is the first of a series of articles that will discuss some of the concepts associated with transcultural nursing. It suggests that nurse education fails in any significant way to deliver culturally sensitive care.
I, Papadopoulos, M, Tilki, J, Alleyne
openaire   +2 more sources

The Education of Nurses

Archives of Otolaryngology - Head and Neck Surgery, 1967
JUST TWO YEARS ago the reasons for the shortage of graduate nurses, particularly for bedside hospital nursing care, were discussed in an editorial in theArchives( 81 :223, 1965). The shortage continues, and with Medicare upon us, grows worse. Why is this so, and cannot something be done about it? The Nov 10 issue of the New England Journal of Medicine
openaire   +2 more sources