Results 221 to 230 of about 304,235 (361)

Fibrates Inhibit PLTP‐induced M2 Macrophage Infiltration and Increase the Sensitivity of Hepatocellular Carcinoma to ICIs

Advanced Science, EarlyView.
Phospholipid transfer protein(PLTP) plays a critical role in forming a complex with kinase A (AURKA) and P65. This interaction facilitates phosphorylation of P65 at Ser536, leading to the activation of the NF‐κB signaling pathway. Ultimately, this leads to the upregulation of downstream cytokines, including IL‐6, IL‐8, and CSF‐1, which promotes M2 ...
Xinyue Liang, Yaning Li, Jianxun Cai, Lisi Luo, Pengfei Yang, Yutong Chen, Jiancong Zhou, Yan Zeng, Jiaping Yu, Weiyu Zhang, Wenzheng Pang, Yufang Li, Chunhua Wen, Jian Li, Linjuan Zeng   +14 more
wiley   +1 more source

The Effects of Educational Level, Work Period, and Motivation on Nurse Care Coordinators’ Performance in Public Health Centers

Social Medicine
Context. The implementation of public health care services at public health centers cannot be separated from the role of nurse care coordinators who carry out these service functions based on the level of education, work period, and motivation of the ...
Nengsih Yulianingsih, Priyanto, Sally Yustinawati Suryatna, Linda Amalia, Lisna Anisa Fitriana   +4 more
doaj  

Improving patient education about tobacco withdrawal and nicotine gum use by registered nurses in inpatient psychiatry: A feasibility study [PDF]

, 2018
Erin Muladore, Jill A. Brown, Judy Haefner, Barbara J. Kupferschmid   +3 more
openalex   +1 more source

Is epistemic injustice a worthy application to mental health nurse education? [PDF]

Nurs Ethics
Fisher J.
europepmc   +1 more source

Nursing education and regulation: international profiles and perspectives

, 2007
This review of nurse education and regulation in selected OECD countries forms part of ongoing work on contemporary nursing careers and working lives, based at the National Nursing Research Unit, King’s College London.
Robinson, Sarah, Griffiths, Peter
core  

TRMT6‐Mediated m1A Modification of CDK9 mRNA Is a Dual‐Pronged Pathogenic Driver for HBV‐Related Hepatocellular Carcinoma

Advanced Science, EarlyView.
TRMT6‐mediated m1A modification in CDK9 mRNA enhances its mRNA stability and translation efficiency, thereby increasing the protein levels of CDK9. Upregulated CDK9 promotes the progression of HCC by elevating the levels of oncogenic factors including p‐STAT3, MCL1, and BCL‐2. On the other hand, CDK9 phosphorylates TARDBP at Ser254 to activate HBV core
Rui Zhang, Dandan Zong, Rui Liu, Yubo Wang, Qingqing Gu, Yao Yao, Wenfang Zheng, Mengmeng Yuan, Simeng Wang, Rongrong Cui, Daxu Li, Siwen Dang, Peng Hou   +12 more
wiley   +1 more source

“The upward spiral staircase of caring”: A hermeneutic phenomenology study of the caring competency of Filipino nurses grounded in competency‐based education [PDF]

, 2019
Emmanuel Dayao Paragas
openalex   +1 more source

COVID 19: Disruptive impacts and transformative opportunities in undergraduate nurse education. [PDF]

Nurse Educ Pract, 2020
Carolan C, Davies CL, Crookes P, McGhee S, Roxburgh M.   +4 more
europepmc   +1 more source

Genome‐Wide CRISPR Screen Identifies a microRNA Orchestrating Pleiotropic Resistance to Targeted Therapy and T Cell Immunity in Melanoma

Advanced Science, EarlyView.
A genome‐wide microRNA CRISPR screen identifies miR‐18a as a master regulator of cross‐resistance in melanoma. Loss of miR‐18a activates the AJUBA–YAP/Hippo axis to confer BRAFi resistance and enhances THBS1–CD47 interaction to impair CD8+ T cell immunity. hnRNP A1 is identified as an upstream regulator of miR‐18a processing.
Zhao Wang, Haotian Liu, Xueqi Wang, Jianjin Teng, Zihan Zheng, Jingya Zhang, Wanyi Xiao, Qian Liang, Jiaxin Li, Xiaomeng Jia, Xin Feng, Hongzhang Cui, Menghan Luo, Tielong Yang, Liuxing Wu, Ke Zhao, Weilong Yang, Mulin Jun Li, Dandan Huang, Jilong Yang   +19 more
wiley   +1 more source

A Mixed-Methods Evaluation of a Maternal Child Health Nurse Education Programme Using Moore's Outcomes Framework for Continuing Medical Education. [PDF]

J Paediatr Child Health
King E, Lim L, Gray A.
europepmc   +1 more source