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Advanced Science, EarlyView.HOXC11 drives colorectal cancer progression by transcriptionally activating CAMK2A, which triggers NF‐κB–dependent CXCL5 upregulation. CXCL5–CXCR2 signaling further reinforces HOXC11 expression through the ERK1/2–SP1 axis, forming a prometastatic positive feedback loop that is effectively disrupted by combined CAMK2A and CXCR2 inhibition.
Qingyang Sun +12 more
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Advanced Science, EarlyView.Oocytes play crucial roles in maintaining ovarian fate in adult gonochoristic fish. Targeted oocyte ablation with aromatase inhibition triggers the activation of surviving germline stem cells and the transdifferentiation of somatic cells from granoulosa/theca to Sertoli/Leydig lineages, inducing a complete and functional female‐to‐male sex reversal ...
Yang Yang +6 more
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Advanced Science, EarlyView.Maternal exercise (ME) increases apelin abundance across maternal and fetal tissues and is associated with improved fetal osteogenesis under POLG mutation‐induced mitochondrial dysfunction. Apelin‐APJ signaling is linked to enhanced mitochondrial function, Akt phosphorylation, and ATF4‐RUNX2 association, supporting coordinated fetal bone remodeling ...
Song Ah Chae +5 more
wiley +1 more source
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Nursing theory in nursing education: An educational imperative
Journal of Professional Nursing, 1992Nursing has accepted theory as basic to its practice; however, the use and development of nursing theory is constrained by the approach used in nursing education. It is not appropriate or sufficient to isolate theory in one course. Moreover, confining nursing theory courses to graduate curricula, which is the custom in many schools of nursing, suggests
L R, Lutjens, M L, Horan
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Evidence Based Nursing, 2018
EBN Perspectives brings together key issues from the commentaries in one of our nursing topic themes.
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EBN Perspectives brings together key issues from the commentaries in one of our nursing topic themes.
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Transcultural nursing and nurse education
British Journal of Nursing, 1994This is the first of a series of articles that will discuss some of the concepts associated with transcultural nursing. It suggests that nurse education fails in any significant way to deliver culturally sensitive care.
I, Papadopoulos, M, Tilki, J, Alleyne
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Nursing and nursing education in Haiti
Nursing Outlook, 2012Haiti has long had the largest proportion of people living in poverty and the highest mortality level of any country in the Americas. On January 12, 2010, the most powerful earthquake to hit Haiti in 200 years struck. Before the earthquake, half of all Haitians lacked any access to modern medical care services. Health care professionals in Haiti number
Richard M, Garfield, Elizabeth, Berryman
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Archives of Otolaryngology - Head and Neck Surgery, 1967
JUST TWO YEARS ago the reasons for the shortage of graduate nurses, particularly for bedside hospital nursing care, were discussed in an editorial in theArchives( 81 :223, 1965). The shortage continues, and with Medicare upon us, grows worse. Why is this so, and cannot something be done about it? The Nov 10 issue of the New England Journal of Medicine
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JUST TWO YEARS ago the reasons for the shortage of graduate nurses, particularly for bedside hospital nursing care, were discussed in an editorial in theArchives( 81 :223, 1965). The shortage continues, and with Medicare upon us, grows worse. Why is this so, and cannot something be done about it? The Nov 10 issue of the New England Journal of Medicine
openaire +2 more sources