Hepatocytes are subjected to increased membrane tension along with lipid accumulation. Loss of PIEZO1 exacerbates high‐fat diet‐induced MASLD in mice. Activation of PIEZO1 alleviates high‐fat diet‐induced MASLD in mice. PIEZO1 negatively regulates de novo lipogenesis through activation of CaMKK2‐AMPK pathway. ABSTRACT Liver is a central organ for lipid
Hui Chen +14 more
wiley +1 more source
The Effect of Education Based on the BASNEF Model on Nurses Communication Skills with Patients in Hospitals Affiliated to Tehran University of Medical Sciences [PDF]
Samira Nazari +2 more
openalex +1 more source
Impact of nurse education prior to and during COVID-19 on nursing students' preparedness for clinical placement: A qualitative study. [PDF]
Brett J +23 more
europepmc +1 more source
Adipocyte‐Derived Leptolin Enhances Energy Expenditure and Prevents Obesity
We identified a novel adipokine, which we named leptolin. In humans, leptolin levels in white adipose tissue were positively correlated with exercise and negatively associated with body mass index. We observed elevated leptolin in serum from athletes and lower leptolin in serum from obese individuals.
Jiarui Liu +17 more
wiley +1 more source
A Critical Need for Advanced Practice Nurse Education in Sub-Saharan Africa and Lessons Learned From the COVID-19 Pandemic: A Discursive Review. [PDF]
Itambo J +3 more
europepmc +1 more source
A Rare Allele of ST5 From Wild Rice Enhances Salt Tolerance in Rice
A novel salt‐tolerance gene ST5W, characterized by a unique 36‐bp promoter insertion, is found exclusively in a small subset of Oryza rufipogon and is absent in cultivated rice. Field trials confirm ST5W significantly enhances rice yield across diverse genetic backgrounds under saline conditions.
Meng Xing +26 more
wiley +1 more source
Dementia: A call for a paradigm shift in pre-registration nurse education. [PDF]
Tuffour I, Ganga G.
europepmc +1 more source
Transition into remote and rural nurse education and careers: a qualitative study of student nurses. [PDF]
Kyle RG, Beattie M, Smith A.
europepmc +1 more source
β‐Adrenergic Signaling Promotes Anti‐Tumor Immunity in TP53‐mutant Oral Squamous Cell Carcinoma
β‐adrenergic stimulation enhances anti‐tumor immunity in TP53‐deficient oral squamous cell carcinoma by inducing tumor‐derived secretion of CXCL10, which attracts and activates cytotoxic CD8+ T cells. The findings demonstrate that β‐adrenergic signaling alters tumor–immune interactions via CXCL10‐mediated paracrine activation, revealing a neuro‐immune ...
Frederico O. Gleber‐Netto +20 more
wiley +1 more source

