Results 151 to 160 of about 9,390 (183)

NUT Midline Carcinoma Masquerading As a Thymic Carcinoma

Journal of Clinical Oncology, 2016
Thymic carcinomas are rare tumors that arise from the epithelium of the thymus gland and characterized by cytologic atypia, invasiveness, and high risk of relapse and death.1–3 The current WHO schema recognizes at least 11 histologic subtypes.4–7 Undifferentiated thymic carcinoma is one of the subtypes that can be indistinguishable from other poorly ...
Gökmen-Polar, Yesim, Kesler, Kenneth, Loehrer, Patrick J., Sr., Badve, Sunil   +3 more
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NUT carcinoma – An aggressive thoracic tumor

The American Journal of the Medical Sciences, 2023
Nuclear protein in testis (NUT) carcinoma is an extremely rare and undifferentiated malignancy characterized by the rearrangement of NUT gene (NUTM1, Nuclear Protein in Testis). NUT carcinoma is a challenging disease which is difficult to diagnose and treat.
Joana Arana, Ribeiro, Jéssica, Sousa, Filipa, Jesus, Élin, Almeida, João Fernandes, Costa, Madalena, Reis, Rita Matos, Gomes   +6 more
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Report of the First International Symposium on NUT Carcinoma

Clinical Cancer Research, 2022
Abstract NUT carcinoma is a rare, aggressive cancer defined by rearrangements of the NUTM1 gene. No routinely effective treatments of NUT carcinoma exist, despite harboring a targetable oncoprotein, most commonly BRD4-NUT. The vast majority of cases are fatal.
Christopher A. French, Michael L. Cheng, Glenn J. Hanna, Steven G. DuBois, Nicole G. Chau, Christine L. Hann, Simone Storck, Ravi Salgia, Matteo Trucco, Jennifer Tseng, Anastasios Stathis, Richard Piekarz, Ulrich M. Lauer, Christophe Massard, Kelly Bennett, Shodeinde Coker, Ulrike Tontsch-Grunt, Martin L. Sos, Sida Liao, Catherine J. Wu, Kornelia Polyak, Sarina A. Piha-Paul, Geoffrey I. Shapiro   +22 more
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The cytologic features of NUT midline carcinoma

Cancer Cytopathology, 2009
AbstractBACKGROUND:Nuclear protein in testis (NUT) midline carcinoma (NMC) represents an aggressive, high‐grade carcinoma typically involving the upper aerodigestive tract or mediastinum. Although the tumor was originally noted in young persons, we have subsequently identified 5 adult cases.
Andrew M, Bellizzi, Cynthia, Bruzzi, Christopher A, French, Edward B, Stelow   +3 more
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NUT Midline Carcinoma

International Journal of Surgical Pathology, 2009
NUT midline carcinoma (NMC) is a recently described, undifferentiated carcinoma with specific NUT gene rearrangement, which often involves midline organs such as the nasal cavity, paranasal sinuses, mediastinum, or intrathoracic organs. It was previously considered a disease of children or young adults, but middle-aged or elderly patients have ...
Min-Shu, Hsieh, Christopher A, French, Cher-Wei, Liang, Cheng-Hsiang, Hsiao   +3 more
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Ultrastructural Features of NUT Midline Carcinoma

Ultrastructural Pathology, 2012
Midline carcinomas associated with the nuclear protein in testis (NUT) gene rearrangement are rare, aggressive tumors that have been diagnosed most commonly in the head, neck, mediastinum, and upper aerodigestive tract. The ultrastructural features associated with this tumor have thus far received only brief comment and have never been illustrated. The
Eric P, Wartchow, Timothy S, Moore, Christopher A, French, Gary W, Mierau   +3 more
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Orbital Involvement by NUT Midline Carcinoma

Ophthalmic Plastic & Reconstructive Surgery, 2015
A 32-year-old female presented with a sino-orbital lesion that proved to be a NUT midline carcinoma. This is only the third case of orbital involvement by this aggressive lesion. The clinical, radiographic, and histopathologic features of NUT midline carcinoma are discussed, as well as its management options.
Jill N, D'Souza, Gregory, Notz, Ronald N, Bogdasarian, David M, Cognetti, Joseph M, Curry, Marc R, Rosen, Madalina, Tuluc, James J, Evans, Jurij R, Bilyk   +8 more
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The Gross Appearance of a NUT Midline Carcinoma

International Journal of Surgical Pathology, 2015
The NUT midline carcinoma (NMC) is a recently described and highly aggressive tumor that usually involves the head and neck and anterior mediastinum. Most patients with NMC present with metastases and are often treated with neoadjuvant chemotherapy and/or radiation therapy.
Jason K, Wasserman, Bibianna, Purgina, Harmanjatinder, Sekhon, Marcio M, Gomes, Chi, Lai   +4 more
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NUT Carcinoma

Applied Radiology, 2021
Jay Kumar Raghavan Nair, Manish Joshi, Mark Hudon, Roderick Simpson, Harold Lau, Christopher French, John Lysack   +6 more
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Metastatic NUT midline carcinoma

Open Journal of Clinical and Medical Images, 2022
NUT Midline Carcinoma (NMC) is a rare carcinoma that presents with rearrangement to the NUTM1 (NUT) gene.
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