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ProtoPred: Advancing Oncological Research Through Identification of Proto-Oncogene Proteins
IEEE Access, 2021 Proto-oncogenes are the genes that have the potential to transform normal cells into cancer cells as a result of mutations. They usually contain encoding of proteins whose function is to inhibit cell differentiation, stimulate cell division, and prevent ...
Sharaf J. Malebary +2 more
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Aberrations of growth factors as biomarkers of cancer progression [PDF]
Archive of Oncology, 2005 Cell proliferation and growth are regulated by a complex network of growth factor and growth inhibitorinitiated signal transduction pathways. The disruption of these signaling pathways through genetic, epigenetic, or somatic alterations is a major area ...
Ivanović Vesna
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Scientific Reports, 2021 USP7, which encodes a deubiquitylating enzyme, is among the most frequently mutated genes in pediatric T-ALL, with somatic heterozygous loss-of-function mutations (haploinsufficiency) predominantly affecting the subgroup that has aberrant TAL1 oncogene ...
Timothy I. Shaw +23 more
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Noncoding RNA Ginir functions as an oncogene by associating with centrosomal proteins. [PDF]
PLoS Biology, 2018 Long noncoding RNAs constitute a major fraction of the eukaryotic transcriptome, and together with proteins, they intricately fine-tune various growth regulatory signals to control cellular homeostasis.
Suchismita Panda +11 more
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Mutation Profile of Well-Differentiated Thyroid Cancer in Asians [PDF]
Endocrinology and Metabolism, 2015 Recent advances in molecular diagnostics have led to significant insights into the genetic basis of thyroid tumorigenesis. Among the mutations commonly seen in thyroid cancers, the vast majority are associated with the mitogen-activated protein kinase ...
Young Shin Song +2 more
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Biomédica: revista del Instituto Nacional de Salud, 2016 Introducción. Uno de los factores de riesgo del carcinoma de células escamosas en la cavidad oral es la infección por el virus del papiloma humano (HPV), cuyas prevalencias dependen de la región geográfica. Objetivo.
Alveiro Erira +5 more
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DISTRIBUTION OF P53 ONCOGENE PROTEINS IN ORAL MALIGNANT LESIONS [PDF]
Acta Medica Iranica, 1995 Immunohi5tochemical determination ofoncogene proteins in human tumors is becoming increasingly important/or obtaining a better understanding ofprocess of tumorigenesis.
Behjat K.H. Moghadam +2 more
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Molecular Cancer, 2019 Though Forkhead box P (FOXP) transcription factors comprising of FOXP1, FOXP2, FOXP3 and FOXP4 are involved in the embryonic development, immune disorders and cancer progression, the underlying function of FOXP3 targeting CD4 + CD25+ regulatory T (Treg ...
Ju-Ha Kim +5 more
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PLoS Pathogens, 2021 Intracellular pathogens have evolved to utilize normal cellular processes to complete their replicative cycles. Pathogens that interface with proliferative cell signaling pathways risk infections that can lead to cancers, but the factors that influence ...
Adrian J Luna +14 more
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Review papers The role of KIT gene mutations in pathogenesis of pediatric mastocytosis
Przegląd Dermatologiczny, 2015 Mastocytosis is characterized by excessive proliferation and accumulation of mast cells in skin and/or other organs. Two forms of the disease, cutaneous and systemic mastocytosis, differ significantly in symptomatology and clinical course.
Joanna Dawicka +5 more
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