Results 161 to 170 of about 634,585 (195)

Therapeutic approaches to sinonasal NUT carcinoma: a systematic review. [PDF]

Eur Arch Otorhinolaryngol
Urbanelli A, Nitro L, Pipolo C, Maccari A, Albera A, Fadda GL, Felisati G, Albera R, Pecorari G, Fuccillo E, Saibene AM.   +10 more
europepmc   +1 more source

Pulmonary NUT carcinoma, an elusive and refractory entity, shows transient response to chemotherapeutics and PD-1 inhibitor: a case report and literature review. [PDF]

Front Immunol
Yang G, Liu R, Yang L, Yang X, Tang X, Mao H.   +5 more
europepmc   +1 more source

Orbital Involvement by NUT Midline Carcinoma

Ophthalmic Plastic & Reconstructive Surgery, 2015
A 32-year-old female presented with a sino-orbital lesion that proved to be a NUT midline carcinoma. This is only the third case of orbital involvement by this aggressive lesion. The clinical, radiographic, and histopathologic features of NUT midline carcinoma are discussed, as well as its management options.
Jill N, D'Souza, Gregory, Notz, Ronald N, Bogdasarian, David M, Cognetti, Joseph M, Curry, Marc R, Rosen, Madalina, Tuluc, James J, Evans, Jurij R, Bilyk   +8 more
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NUT carcinoma of the lung

Seminars in Diagnostic Pathology, 2021
NUT carcinoma of the thorax is a rare and very aggressive tumor, whose definition is based on the demonstration of a nuclear protein in testis (NUTM1; also known as NUT) gene fusion on 15q14 with different partners from the bromodomain-containing proteins gene family.
Sylvie, Lantuejoul, Daniel, Pissaloux, Gilbert R, Ferretti, Anne, McLeer   +3 more
openaire   +2 more sources

Clinicopathological and Preclinical Findings of NUT Carcinoma: A Multicenter Study [PDF]

Oncologist, 2019
Background: NUT carcinoma is a rare aggressive disease caused by BRD4/3-NUT fusion, and C-MYC upregulation plays a key role in the pathogenesis. Here, we report on the clinicopathological characteristics of Korean patients with NUT carcinoma and the in ...
Dong-Wan Kim, Dae Seog Heo, Tae Min Kim
exaly   +3 more sources

NUT carcinoma in children and adults: A multicenter retrospective study

Pediatric Blood and Cancer, 2017
Background: Nuclear protein of the testis (NUT) carcinoma (formerly NUT midline carcinoma) is an aggressive tumor defined by the presence of NUT rearrangement with a poor prognosis. This rare cancer is underdiagnosed and poorly treated.
Christophe le Tourneau, Daniel Orbach, Matthieu Carton   +2 more
exaly   +2 more sources

Metastatic NUT Carcinoma in a Child

Indian Journal of Otolaryngology and Head & Neck Surgery, 2023
Nuclear protein of the testis (NUT) carcinoma is a rare and aggressive malignancy associated with rearrangements of the NUT gene on chromosome 15q14 .This entity is often under diagnosed and there is limited literature regarding its biology and optimal management.
Daphne Fonseca, Suseela Kodandapani, Rayala Vikas Babu, Chandrasekhara Rao, Subramanyeshwar Rao   +4 more
openaire   +2 more sources

Imaging spectrum of NUT carcinomas

Clinical Imaging, 2020
Nuclear protein of the testis (NUT) carcinoma (NC) (formerly known as NUT midline carcinoma) is an aggressive pleomorphic squamous cell carcinoma with a dismal prognosis. Primary NC tumors are commonly located in the chest or head and neck regions.
Mayur, Virarkar, Mohammed, Saleh, Nisha Subhashchandra, Ramani, Ajaykumar C, Morani, Priya, Bhosale   +4 more
openaire   +2 more sources

NUT carcinoma – An aggressive thoracic tumor

The American Journal of the Medical Sciences, 2023
Nuclear protein in testis (NUT) carcinoma is an extremely rare and undifferentiated malignancy characterized by the rearrangement of NUT gene (NUTM1, Nuclear Protein in Testis). NUT carcinoma is a challenging disease which is difficult to diagnose and treat.
Joana Arana, Ribeiro, Jéssica, Sousa, Filipa, Jesus, Élin, Almeida, João Fernandes, Costa, Madalena, Reis, Rita Matos, Gomes   +6 more
openaire   +2 more sources

NUT Midline Carcinoma Masquerading As a Thymic Carcinoma

Journal of Clinical Oncology, 2016
Thymic carcinomas are rare tumors that arise from the epithelium of the thymus gland and characterized by cytologic atypia, invasiveness, and high risk of relapse and death.1–3 The current WHO schema recognizes at least 11 histologic subtypes.4–7 Undifferentiated thymic carcinoma is one of the subtypes that can be indistinguishable from other poorly ...
Gökmen-Polar, Yesim, Kesler, Kenneth, Loehrer, Patrick J., Sr., Badve, Sunil   +3 more
openaire   +2 more sources