Results 1 to 10 of about 36,453 (235)

Autophagy signaling in hypertrophied muscles of diabetic and control rats

FEBS Open Bio, Volume 13, Issue 9, Page 1709-1722, September 2023., 2023
We analyzed autophagy proteins in extensor digitorum longus (EDL) and soleus muscles of control and diabetic rats after 7 days of hypertrophy. Basal autophagy proteins were higher in EDL. Diabetes did not affect the hypertrophy or autophagy in either muscle. Soleus showed increased autophagy signaling after hypertrophy.
Maria V. M. Scervino, Marco A. S. Fortes, Kaio F. Vitzel, Diego R. de Souza, Gilson M. Murata, Giovanna O. Santana, Eliane B. da Silva, Adriana C. Levada‐Pires, Wilson M. T. Kuwabara, Tatiana C. A. Loureiro, Rui Curi   +10 more
wiley   +1 more source

Different antihypertensive and metabolic responses to rostafuroxin in undernourished and normonourished male rats: Outcomes on bodily Na+ handling

Physiological Reports, Volume 11, Issue 17, September 2023., 2023
Rostafuroxin, an antagonist of endogenous cardiotonic steroids, has different effects in rats depending on their nutritional status. In undernourished hypertensive rats, the drug exerts hypotensive, antinatriuretic, and diuretic actions. In normonourished normotensive animals, these actions are not seen; notably, the drug acts as a natriuretic agent ...
Amaury Pereira‐Acácio, João P. M. Veloso‐Santos, Danilo Alves‐Bezerra, Glória Costa‐Sarmento, Humberto Muzi‐Filho, Adalberto Vieyra   +5 more
wiley   +1 more source

Cellular senescence in skin‐related research: Targeted signaling pathways and naturally occurring therapeutic agents

Aging Cell, Volume 22, Issue 6, June 2023., 2023
Aging and external stressors including exposure to UV light promote senescence of keratinocytes accelerating aging process. Development of effective plant‐based senotherapeutics represent novel approaches for senescent‐related skin disorders and can be used in cosmetic skin changes related to aging.
Aleksandra Dańczak‐Pazdrowska, Justyna Gornowicz‐Porowska, Adriana Polańska, Violetta Krajka‐Kuźniak, Maciej Stawny, Aleksandra Gostyńska, Błażej Rubiś, Sarah Nourredine, Sarah Ashiqueali, Augusto Schneider, Tamara Tchkonia, Saranya P. Wyles, James L. Kirkland, Michal M. Masternak   +13 more
wiley   +1 more source

Understanding and controlling asthma in Latin America: A review of recent research informed by the SCAALA programme

Clinical and Translational Allergy, Volume 13, Issue 3, March 2023., 2023
Abstract Asthma is an important health concern in Latin America (LA) where it is associated with variable prevalence and disease burden between countries. High prevalence and morbidity have been observed in some regions, particularly marginalized urban populations.
Philip J. Cooper, Camila A. Figueiredo, Alejandro Rodriguez, Leticia Marques dos Santos, Rita C. Ribeiro‐Silva, Valdirene Leao Carneiro, Gustavo Costa, Thiago Magalhães, Talita dos Santos de Jesus, Raimon Rios, Hugo Bernardino F. da Silva, Ryan Costa, Martha E. Chico, Maritza Vaca, Neuza Alcantara‐Neves, Laura C Rodrigues, Alvaro A. Cruz, Mauricio L. Barreto   +17 more
wiley   +1 more source

Antioxidant Mechanisms Underlying the Gastroprotective Effect of Menthofuran on Experimentally Induced Gastric Lesions in Rodents

Evidence-Based Complementary and Alternative Medicine, Volume 2023, Issue 1, 2023., 2023
Menthofuran is a monoterpene present in various essential oils derived from species from Mentha genus, and in Brazil, those species are widely used in treating gastrointestinal and respiratory disorders. Considering the wide pharmacological potential of monoterpenes, including their antioxidant activity, this study aimed to evaluate menthofuran ...
Naira Moura Alves, Paulo Humberto Moreira Nunes, Anderson Mendes Garcez, Manoela Carine Lima de Freitas, Irisdalva Sousa Oliveira, Francilene Vieira da Silva, Hélio de Barros Fernandes, Damião Pergentino de Sousa, Rita de Cássia Meneses Oliveira, Daniel Dias Rufino Arcanjo, Maria do Carmo de Carvalho e Martins, Atul Kabra   +11 more
wiley   +1 more source

Performance of subjective global nutritional assessment in predicting clinical outcomes: Data from the Brazilian survey of pediatric oncology nutrition

Cancer Medicine, Volume 11, Issue 23, Page 4612-4623, December 2022., 2022
Abstract Background Methods for assessing nutritional status in children and adolescents with cancer is a difficult in clinical practice. The study aimed to evaluate the performance of Subjective Global Nutritional Assessment (SGNA) in predicting clinical outcomes in children and adolescents with cancer in Brazil.
Wanélia Vieira Afonso, Wilza Arantes Ferreira Peres, Nivaldo Barroso de Pinho, Arthur Orlando Corrêa Schilithz, Renata Brum Martucci, Viviane Dias Rodrigues, Barbara Folino Nascimento, Carolina Ferraz Figueiredo Moreira, Patricia de Carvalho Padilha   +8 more
wiley   +1 more source

Assessment of genetically modified soybean 40‐3‐2 for renewal authorisation under Regulation (EC) No 1829/2003 (application EFSA‐GMO‐RX‐023)

EFSA Journal, Volume 20, Issue 12, December 2022., 2022
Abstract Following the submission of application EFSA‐GMO‐RX‐023 under Regulation (EC) No 1829/2003 from Bayer Agriculture BV on behalf of Bayer CropScience LP, the Panel on Genetically Modified Organisms of the European Food Safety Authority was asked to deliver a scientific risk assessment on the data submitted in the context of the renewal of ...
EFSA Panel on Genetically Modified Organisms (GMO), Ewen Mullins, Jean‐Louis Bresson, Tamas Dalmay, Ian Crawford Dewhurst, Michelle M Epstein, Leslie George Firbank, Philippe Guerche, Jan Hejatko, Francisco Javier Moreno, Hanspeter Naegeli, Fabien Nogué, Nils Rostoks, Jose Juan Sánchez Serrano, Giovanni Savoini, Eve Veromann, Fabio Veronesi, Ana M Camargo, Tilemachos Goumperis, Paolo Lenzi, Aleksandra Lewandowska, Tommaso Raffaello, Franz Streissl   +22 more
wiley   +1 more source

Gill and haematological alterations in Macrobrachium amazonicum adults in acute exposure to ammonia and nitrite isolated and combined

Aquaculture, Fish and Fisheries, Volume 2, Issue 5, Page 414-424, October 2022., 2022
Total ammonia and nitrite combined generated antagonism. Less severe damage occurred on gills exposed to ammonia and nitrite. High THC are found in the highest concentrations of the nitrogen compounds. Abstract The present study evaluated the isolated and combined effect of total ammonia and nitrite on Macrobrachium amazonicum adults through the median
Fabrício Martins Dutra, Jonatan Raphael Juvenal, Sandra Carla Forneck, Claudia Caramelo Brazão, Eduardo Luis Cupertino Ballester   +4 more
wiley   +1 more source

Development and validation of an instrument to assess Brazilians’ knowledge, perceptions, and behaviors toward salt and sodium

The Journal of Clinical Hypertension, Volume 24, Issue 5, Page 555-565, May 2022., 2022
Abstract This study aimed to develop and validate an instrument to assess Brazilian adults’ knowledge, perceptions, and behaviors (KPB) toward salt and sodium. Based on a PAHO/WHO questionnaire, a new instrument was developed and evaluated by 11 experts, generating item and scale‐level content validity indexes (I‐CVI and S‐CVI, respectively).
Alícia Tavares da Silva Gomes, Kamila Tiemann Gabe, Patricia Constante Jaime   +2 more
wiley   +1 more source

Profile of cognitive impairment in late‐stage Parkinson's disease

Brain and Behavior, Volume 12, Issue 4, April 2022., 2022
We have characterized the cognitive profile of 84 LSPD patients. Almost all LSPD patients presented cognitive impairment. Fifty‐four LSPD patients (64%) were classified as demented, most of them presented a global impairment profile, with both Alzheimer's and PD‐typical impairments. Twenty‐five patients (30%) presented mild cognitive impairment, mainly
Catarina Severiano e Sousa, Margherita Fabbri, Catarina Godinho, Rita Moiron Simões, Inês Chendo, Miguel Coelho, Isabel Pavão Martins, Joaquim J. Ferreira   +7 more
wiley   +1 more source