Results 121 to 130 of about 1,218,343 (310)

Circulating microRNA signatures of cachexia and cancer in Canis familiaris as a comparative oncology model for human disease

open access: yesMolecular Oncology, EarlyView.
Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).
Soon‐Seok Park   +6 more
wiley   +1 more source

Enhancing Maize Yield and Nutrient Utilization through Improved Soil Quality under Reduced Fertilizer Use: The Efficacy of Organic–Inorganic Compound Fertilizer

open access: yesAgriculture
Objectives: The substitution of chemical fertilizers with organic alternatives presents a viable strategy for enhancing soil quality and boosting agricultural productivity.
Xiaoying Chen   +7 more
doaj   +1 more source

Preoperative circulating tumor cells integrated with imaging analysis for prognostic evaluation in head and neck squamous cell carcinoma

open access: yesMolecular Oncology, EarlyView.
Detecting circulating tumor cells (CTCs) in blood before surgery may help predict outcomes in patients with head and neck squamous cell carcinoma (HNSCC). Here, we show when combined with tumor size and lymph node involvement from routine imaging, CTC status identifies high‐risk patients with poorer survival—offering a simple, minimally invasive tool ...
Susanne Flach   +9 more
wiley   +1 more source

Trends in productivity and nutrient dynamics under improved soil nutrient management techniques for rice in the rainfed lowlands of Cambodia [PDF]

open access: yes, 2010
Increasing rice yields in rainfed lowlands of Cambodia relies on better understanding of balanced nutrition and matching crop demand with nutrient supply.
Bell, R.W.   +4 more
core  

Integrative analysis of endogenous phytohormones and transcriptomics reveals mechanism of light-induced callus formation in tea (Camellia sinensis) cuttings

open access: yesBMC Plant Biology
Backgroud Cutting is the mainly asexual propagation method for tea plant, and moreover, callus formation is a key point for the survival rate of tea cuttings. As reported, light is crucial for callus formation of tea cuttings via influencing phytohormone
Ying Gao   +9 more
doaj   +1 more source

Greenhouse gas emission and cadmium contamination in rice paddies: research progresses in trade-off relationships, influencing factors and synergistic mitigation measures

open access: yesFrontiers in Sustainable Food Systems
Rice paddies, critical for global food security, confront dual challenges of greenhouse gas (GHG, e.g., CH4, N2O) emissions and cadmium (Cd) contamination.
Gaoxiang Qi   +13 more
doaj   +1 more source

Epigenetic silencing of the liver‐specific lncRNA LUNAR promotes liver cancer progression via NOTCH activation

open access: yesMolecular Oncology, EarlyView.
LUNAR is a liver‐specific long noncoding RNA (lncRNA) that is highly expressed in normal liver but becomes epigenetically silenced in hepatocellular carcinoma through promoter hypermethylation. Loss of LUNAR is associated with NOTCH activation, epithelial–mesenchymal transition, and metastasis, whereas restoring LUNAR restrains metastatic progression ...
Se Ha Jang   +9 more
wiley   +1 more source

Targeting transcription factors associated with hemoglobinopathies: Lessons from successful interventions and implications for cancer

open access: yesMolecular Oncology, EarlyView.
This review summarizes the transcription factors, repressive chromatin‐modifying complexes, and epigenetic mechanisms that control fetal hemoglobin repression. Notably, many regulators of γ‐globin silencing also function in transcriptional and epigenetic networks that drive cancer, highlighting opportunities to translate advances in hemoglobinopathy ...
Meigen Yu   +3 more
wiley   +1 more source

Pyramiding of Low-Nitrogen-Responsive QTL Clusters Enhances Yield and Nutrient-Use Efficiency in Barley

open access: yesAgriculture
Given that nitrogen (N) is a major limiting factor for global crop production, improving low-nitrogen (LN) tolerance in barley is essential for sustaining yields worldwide.
Bing-Jie Chen   +9 more
doaj   +1 more source

ADP‐ribosylation: An emerging regulator of the epigenome

open access: yesMolecular Oncology, EarlyView.
ADP‐ribosylation has emerged as a dynamic epigenetic signaling mechanism that modifies histones and chromatin‐associated proteins. Through coordinated PARylation and MARylation, it integrates with other histone modifications to regulate chromatin structure, transcription factor activity, and gene expression, influencing genome function and disease ...
Cristel V. Camacho   +2 more
wiley   +1 more source

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