Results 61 to 70 of about 885,660 (315)

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Gene coexpression network analysis of fruit transcriptomes uncovers a possible mechanistically distinct class of sugar/acid ratio-associated genes in sweet orange

BMC Plant Biology, 2017
Background The ratio of sugars to organic acids, two of the major metabolites in fleshy fruits, has been considered the most important contributor to fruit sweetness. Although accumulation of sugars and acids have been extensively studied, whether plants
Liang Qiao, Minghao Cao, Jian Zheng, Yihong Zhao, Zhi-Liang Zheng   +4 more
doaj   +1 more source

Colorectal cancer‐derived FGF19 is a metabolically active serum biomarker that exerts enteroendocrine effects on mouse liver

Molecular Oncology, EarlyView.
Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley, Michael W. Rohr, Joseph A. Goode, Sai Preethi Nakkina, Jignesh G. Parikh, Deborah A. Altomare   +5 more
wiley   +1 more source

Humic Acid Promotes the Growth of Switchgrass under Salt Stress by Improving Photosynthetic Function

Agronomy
As a potential crop in saline-alkali land, the growth of switchgrass could also be threatened by salt stress. Promoting the growth of switchgrass under salt stress by humic acid has great significance in the utilization of saline-alkali land.
Jiaxing Zhang, Qiuxia Meng, Zhiping Yang, Qiang Zhang, Min Yan, Xiaochan Hou, Xunzhong Zhang   +6 more
doaj   +1 more source

Reduced-nutrient leachates in cash cover crop-soybean systems [PDF]

, 2018
Matthew D. Thom, Frank Forcella, Carrie A. Eberle, Heather L. Matthees, Sharon L. Weyers, Russ W. Gesch, Matthew Ott, Gary W. Feyereisen, Jeffrey S. Strock, Don Wyse   +9 more
openalex   +1 more source

Identification of serum protein biomarkers for pre‐cancerous lesions associated with pancreatic ductal adenocarcinoma

Molecular Oncology, EarlyView.
This work identified serum proteins associated with pancreatic epithelial neoplasms (PanINs) and early‐stage PDAC. Proteomics screens assessed genetically engineered mice with abundant PanINs, KPC mice (Lox‐STOP‐Lox‐KrasG12D/+ Lox‐STOP‐Lox‐Trp53R172H/+ Pdx1‐Cre) before PDAC development and also early‐stage PDAC patients (n = 31), compared to benign ...
Hannah Mearns, Jaclyn S. Long, Sergio Lilla, Kelly Hodge, Marcus J. G. W. Ladds, Colin Nixon, Paula Fernández‐Palanca, Sara Zanivan, Pilar Acedo, Stephen P. Pereira, Kevin M. Ryan   +10 more
wiley   +1 more source

Effects of Maize–Lablab Intercropping and Lactic Acid Bacteria Additives on Forage Yield, Fermentation Quality and Profitability

Fermentation
Intercropping systems and exogenous microorganism additives are recognized for their potential to influence silage fermentation and quality. This study aims to evaluate the impacts of maize–lablab bean intercropping and lactic acid bacteria (LAB ...
Dongsheng Li, Hongyang Ren, Linfeng Zheng, Yue Hou, Hongliang Wang   +4 more
doaj   +1 more source

Persistence and resistance: survival mechanisms of Candidatus Dormibacterota from nutrient‐poor Antarctic soils [PDF]

, 2022
Kate Montgomery, Timothy J. Williams, Merryn Brettle, Jonathan F. Berengut, Eden Zhang, Julian Zaugg, Philip Hugenholtz, Belinda C. Ferrari   +7 more
openalex   +1 more source

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

Molecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova, Zuzana Kozovska, Ondrej Pos, Kristina Pavlov, Sachin Gulati, Peter Makovicky, Kristina Jakic, Monika Burikova, Eva Sedlackova, Barbora Svitkova, Silvia Tyciakova, Vojtech Bystry, Nicolas Blavet, Boris Tichy, Matej Hrnciar, Jaroslav Budis, Miroslav Tomas, Peter Dubovan, Georgina Kolnikova, Veronika Repaska, Nikoleta Mojzesova, Eva Zomborska, Daniel Pindak, Michal Mego, Tomas Szemes, Miroslava Matuskova   +25 more
wiley   +1 more source

Synergistic nitrification inhibitors with best management practices can achieve higher yield and nitrogen use efficiency in semi-arid saline-alkali soils

Scientific Reports
High yield and high nitrogen use efficiency are blocked by various abiotic stress, especially in arid, salinity and irrigation deficiency agricultural production system.
Zixin Zeng, Linmei Wu, Jiahuan Liu, Zengyuan Li, Bei Li, Zhiping Duan, Weifeng Zhang   +6 more
doaj   +1 more source