Results 81 to 90 of about 3,201,549 (279)

Structural and biochemical analysis of a B12 superbinder

FEBS Letters, EarlyView.
BtuG proteins are vitamin B12 scavengers in Bacteroides thetaiotaomicron, a dominant human gut bacterium. We present crystal structures of three BtuG homologs bound to cobalamin and its precursor cobinamide, revealing picomolar binding affinities, among the highest known for any natural protein.
Jose M. Martinez Felices, Jacob J. Whittaker, Dirk J. Slotboom, Albert Guskov   +3 more
wiley   +1 more source

CALCULATION AND COMPARISON OF NUTRIENT DENSITY/QUALITY SCORES FOR COMMONLY CONSUMED FRESH FRUIT

Alimentos e Nutrição, 2012
A number of methods have been developed to quantitatively describe the nutrient density/quality (ND/Q) of foods and beverages. Seventeen commonly consumed fresh fruits were evaluated using six published ND/Q methods. Nutrient data for each fruit were
Gail RAMPERSAUD, Maria Filomena VALIM, Sandy BARROS   +2 more
doaj  

Interactive effects of dietary energy levels with amino acid density on growth performance and optimal digestible Lys to energy ratio of male broiler chickens

Poultry Science
: A total of 2,400 day-old off-sex male Ross 308 chicks were used in a 4 × 3 factorial array (8 replicates with 25 birds per replicate) to determine the interactive effects of dietary metabolizable energy (ME) and amino acid (AA) densities on productive ...
Mehdi Toghyani, Shemil MacElline, Peter H. Selle, Sonia Y. Liu   +3 more
doaj   +1 more source

L‐aspartate oxidase provides new insights into fumarate reduction in anaerobic darkness in Synechocystis sp. PCC6803

FEBS Letters, EarlyView.
Synechocystis strains deficient in succinate dehydrogenase (SDH) secrete more succinate than the WT under dark anaerobic conditions, supporting that SDH then primarily acts as SDH, not as a fumarate reductase. L‐aspartate oxidase (Laspo) from Synechocystis is functional under anaerobic conditions, reducing fumarate to succinate.
Kateryna Kukil, Jeffrey A. Hawkes, Cecilia Blikstad, Pia Lindberg   +3 more
wiley   +1 more source

Comparison of Nutrient Density and Nutrient-to-Cost Between Cooked and Canned Beans

Food and Nutrition Sciences, 2011
Consumption of nutrient rich foods such as beans and peas is recommended because these foods provide key nutrients and relatively little energy. Many consumers are unfamiliar with dried beans or do not have the time to prepare them. The purpose of this study was to compare nutrient density and nutrient-to-cost among dried cooked, canned (liquid and ...
Michael Zanovec, Carol E. O' Neil, Theresa A. Nicklas   +2 more
openaire   +2 more sources

Metastatic niche shaped by host factors influences disseminated cancer cell fate

FEBS Letters, EarlyView.
Metastasis is shaped not only by cancer cells but also by the environments they encounter. This review explores how factors such as aging, diet, the microbiome, lifestyle, and environmental exposures remodel organ‐specific niches in the lung, liver, bone, and brain, influencing where metastatic cells survive, remain dormant, or grow, and ultimately ...
Gwennan Delyth Ward, Álvaro Ruiz‐Tabas, Patricia Altea‐Manzano   +2 more
wiley   +1 more source

An Alarming Decline in the Nutritional Quality of Foods: The Biggest Challenge for Future Generations’ Health

Foods
In the last sixty years, there has been an alarming decline in food quality and a decrease in a wide variety of nutritionally essential minerals and nutraceutical compounds in imperative fruits, vegetables, and food crops. The potential causes behind the
Raju Lal Bhardwaj, Aabha Parashar, Hanuman Prasad Parewa, Latika Vyas   +3 more
doaj   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Global imaging of the Earth's deep interior: seismic constraints on (an)isotropy, density and attenuation [PDF]

, 2013
Seismic tomography is the principal tool to probe the deep interior of the Earth. Models of seismic anisotropy induced by crystal alignment provide insight into the underlying convective motion, and variations of density allow us to discriminate between ...
Karato, S.-I., Seismology, Andreas Fichtner, NWO-VIDI: Full waveform inversion for upper-mantle density structure, Trampert, J., Fichtner, A., ISES: Hunting for density in the upper mantle using a 3D wave propagation code together with adjoint techniques, Jeannot Trampert   +7 more
core   +1 more source

Stimulator of interferon genes agonist augmented antitumor immunity of osimertinib in Egfr‐mutated lung cancer

Molecular Oncology, EarlyView.
Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura, Tadahiro Kuribayashi, Johannes Brägelmann, Sachi Okawa, Masataka Taoka, Shunta Mori, Tomoka Nishimura, Takaaki Tanaka, Go Makimoto, Kiichiro Ninomiya, Kammei Rai, Eiki Ichihara, Ryohei Katayama, Katsuyuki Hotta, Masahiro Tabata, Yosuke Togashi, Yoshinobu Maeda, Martin L. Sos, Katsuyuki Kiura, Kadoaki Ohashi   +19 more
wiley   +1 more source