Results 31 to 40 of about 30,177 (218)

Membrane composition and thermodynamic identity as boundaries of life for synthetic cell research

FEBS Letters, EarlyView.
What makes a cell a cell? The boundary of a living cell is not just a wall. Read as a Markov blanket, the membrane separates internal from external states, generating identity and non‐equilibrium order. Can this identity be rebuilt from scratch in a synthetic cell?
Caterina Presutti, Bert Poolman
wiley   +1 more source

A taste for growth: Rapeseed lecithin improves the feed intake of post‐juvenile rainbow trout (Oncorhynchus mykiss)

Journal of the World Aquaculture Society
Feed formulations low in fish meal and fish oil can decrease feed intake and nutrient digestibility. Dietary application of lecithins could improve growth performance and nutrient digestibility; however, knowledge about specific lecithins and their ...
Frederik Kaiser, Michael Schlachter, Anja Diekenhorst van derSande, Carsten Schulz   +3 more
doaj   +1 more source

Polymorphism of MC4R gene associated with feed intake, nutrient digestibility, ADG and FCR at post-weaning in Bligon goats

Journal of the Indonesian Tropical Animal Agriculture, 2020
The melanocortin-4 receptor (MC4R) gene plays an important role in sympathetic nerve activity, as well as adrenal and thyroid function and mediates the effects of leptin on energy homeostasis.
L. Latifah, D. Maharani, K. Kustantinah, T. Hartatik   +3 more
doaj   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Nutritional potential of kenaf grain meal as a replacement for palm kernel cake in cassava peel-based concentrate for sheep

Agricultura Tropica et Subtropica, 2021
The study evaluated the nutrient intake, apparent nutrient digestibility, performance and nitrogen balance of West African Dwarf (WAD) sheep fed cassava peel-based diets containing kenaf grain meal (KGM) in replacement of palm kernel cake (PKC).
Omotoso Sunday Oloruntoba, Ajayi Festus Temitope, Kenneth-Obosi Olusimbo, Oladele-Bukola Mutiu Olakunle   +3 more
doaj   +1 more source

Effect of dietary peNDF levels on digestibility and rumen fermentation, and microbial community in growing goats

Frontiers in Microbiology, 2022
Physically effective neutral detergent fiber (peNDF) is a concept that accounts for the particle length of NDF in diets, sustaining the normal chewing behavior and rumen fermentation of ruminants.
Jia Zhou, Benchu Xue, Anhai Hu, Shuangming Yue, Mei Wu, Qionghua Hong, Yuhan Wu, Zhisheng Wang, Lizhi Wang, Quanhui Peng, Bai Xue   +10 more
doaj   +1 more source

PAK1 activation drives divergent resistance mechanisms to aromatase inhibition and tamoxifen in a luminal: A breast cancer model

Molecular Oncology, EarlyView.
Breast cancer remains a major cause of cancer death in women, frequently developing endocrine therapy resistance. This study demonstrates that upregulated p21‐activated kinase 1 (PAK1) activity drives resistance to tamoxifen and long‐term estrogen deprivation in ER+ breast cancer models.
Luisa Schwarzmüller, Janina Müller, Efstathios‐Iason Vlachavas, Lukas Beumers, Lena Fleischhacker, Sara Burmester, Angelika Wörner, Sabine Karolus, Dominic Helm, Cindy Körner, Stefan Wiemann   +10 more
wiley   +1 more source

Soybean meal nutrient composition, amino acid digestibility, and energy content according to the country of origin and year of harvest evaluated via NIRS

Journal of Applied Poultry Research
SUMMARY: Considerable variability has been reported for soybean meal (SBM) nutrient and energy content and protein and amino acid (AA) digestibility. Furthermore, analytical variability among labs can introduce bias in feedstuff valuation.
E.O. Oviedo-Rondón, A. Toscan, N.S. Fagundes, J.K. Vidal, J. Barbi, P. Thiery   +5 more
doaj   +1 more source

Effects of dietary brown propolis on nutrient intake and digestibility in feedlot lambs

Revista Brasileira de Zootecnia, 2014
The present study tested brown propolis in crude or extract form as a feed supplement for feedlot lambs to identify the type that most improves in vivo nutrient digestibility. Digestibility was assessed by both total fecal collection and internal markers
Jonilson Araújo da Silva, Camila Celeste Brandão Ferreira Ítavo, Luís Carlos Vinhas Ítavo, Maria da Graça Morais, Gumercindo Loriano Franco, Lucia Maria Zeoula, Natália da Silva Heimbach   +6 more
doaj   +1 more source

Inhibition of cyclin‐dependent kinases 12/13 using CT7439 as a treatment for colorectal cancer with CDK12 upregulation

Molecular Oncology, EarlyView.
The proposed mechanism of action for the CDK12/13 inhibitor and cyclin K degrader, CT7439. CDK12/13 inhibition interrupts transcription elongation, leading to increased DNA damage that results in cell death. This agent is a potentially novel treatment option for patients with colorectal cancer. Created in BioRender. Cyclin‐dependent kinase (CDK) 12 and
Wylie K. Watlington, Divya L. Dayanidhi, Mohammad Zokaasadi, John B. Mantyh, Pelumi D. Olawuni, Gabrielle Rupprecht, Jeremy M. Force, Shannon McCall, Ashwani K. Bahl, David S. Hsu, Jason A. Somarelli   +10 more
wiley   +1 more source