Results 61 to 70 of about 903,910 (312)

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

open access: yesFEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

Modelling the behaviour of nutrients in the coastal waters of Scotland [PDF]

open access: yes, 2002
The overall goal of this project was to provide Scotland with a strategic ecosystem simulation tool for identifying maritime areas which could be at risk of eutrophication.
Turrell, W.R.   +5 more
core   +3 more sources

Nutrients and Muscle Disease [PDF]

open access: yesBioMed Research International, 2015
Myopathies, classified as either hereditary or acquired, lead to common, clinically relevant complaints including fatigue, progressive strength loss, myalgias, and cramps. Important progress has been made in the comprehension of the molecular mechanisms underlying muscle diseases but, in the majority of cases, their clinical management is symptom ...
E. Nisoli, R. Grange, G. D'Antona
openaire   +3 more sources

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

open access: yesFEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa   +2 more
wiley   +1 more source

Modelling stem cell differentiation related processes—A practical overview for biologists

open access: yesFEBS Letters, EarlyView.
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar   +4 more
wiley   +1 more source

Cold exposure reinstates NAD+ levels and attenuates hepatocellular carcinoma

open access: yesCell Stress
Cold exposure has been historically used for medicinal purposes, but its benefits and associated mechanisms in mammalian organisms still remain unclear.
Tatiana P Grazioso   +4 more
doaj   +1 more source

Estimating Excreted Nutrients to Improve Nutrient Management for Grazing System Dairy Farms

open access: yesAnimals, 2023
Improving nutrient management in grazing system dairy farms requires determining nutrient flows through animals, the placement of cows within farms and potential for collection, and the re-use and loss of nutrients.
Sharon R. Aarons   +2 more
doaj   +1 more source

Nutrient Adequacy

open access: yes, 2014
Key Messages "Nutrient adequacy, a result of consumption of sufficient amounts of all essential nutrients and energy to meet individual requirements, is a prerequisite for normal growth, development and health. " Two thirds or more of hospital patients suffer from malnutrition at initial presentation.
openaire   +3 more sources

Why Nutrients? [PDF]

open access: yesNutrients, 2009
The field of nutrition continues to attract increasing interest from health professionals, including dietitians, sports nutritionists and medical practitioners, from biomedical, agricultural, nutritional and food scientists and from health conscious consumers alike. [...]
openaire   +2 more sources

Design and analysis strategies for robust microbiome ageing research

open access: yesFEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik   +5 more
wiley   +1 more source

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