Results 81 to 90 of about 903,910 (312)
Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential
FEBS Letters, EarlyView.Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta +3 more
wiley +1 more source
, 2017 The Nutrients Editorial Office has recently been made aware that the figures in the title paper [1] are taken from the same micrographs as those of other papers by the same authors [...
Nutrients Editorial Office
core +1 more source
Industrial Crops and ProductsFicus hirta Vahl is a bioactive medicinal plant. However, the structural and functional differences of polysaccharides obtained through various extraction methods remain poorly understood, highlighting the need for further research to explore its ...
Ting Ju +8 more
doaj +1 more source
Structure‐forward targeting of claudins with synthetic binders
FEBS Letters, EarlyView.Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley +1 more source
, 2019 The prevention of bone mass loss and related complications associated with osteoporosis is a significant public health issue. The Mediterranean diet (MD) is favorably associated with bone health, a potentially modifiable risk factor.
Agüero Martínez, Maria dels Àngels +10 more
core +1 more source
FEBS Letters, EarlyView.Animals must match their growth rate to available nutrients. We show that in Drosophila larvae, the nutrient‐sensing TOR kinase controls growth by regulating levels of TFAM, a key regulator of mitochondrial function, in the adipose tissue. When nutrients are abundant, high TOR activity suppresses TFAM, lowering mitochondrial bioenergetic activity and ...
Shrivani Sriskanthadevan‐Pirahas +4 more
wiley +1 more source
Liver organoids: modelling complexity in homeostasis and disease
FEBS Letters, EarlyView.Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley +1 more source
, 2019 Concentrations of nutrients in the plant parts (L – leaf, R – root, S – stem) of M. bisulcata seedlings (survivors) from the forest experiment using mesh bags. N, P, Ca, K and Mg are in mg/g, and Al, Fe, Mn, Cu and Zn are in mg/100g, dry mass.
David M. Newbery (2914190) +3 more
core +1 more source
Biogeochemical nutrient cycles and nutrient management strategies [PDF]
Hydrobiologia, 1999 Nutrient loading by riverine input into estuarine systems has increased by 6–50 times for the N load from pristine conditions to present, whereas a 18–180 times increase has been observed in the P load. Reductions in the ratio of N to P delivery has also occurred with time.
openaire +2 more sources