Results 71 to 80 of about 798,658 (316)

Acknowledgement to Reviewers of Nutrients in 2019 [PDF]

, 2020
The editorial team greatly appreciates the reviewers who have dedicated their considerable time and expertise to the journal’s rigorous editorial process over the past 12 months, regardless of whether the papers are finally published or not [...
Nutrients Editorial Office
core   +1 more source

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

FEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai, Mizuki Seo, Gyath Karadsheh, Fachrur Rizal Mahendra, Máté Á Demény, Ferenc Győry, János András Mótyán, László Fésüs, Endre Kristóf, Rini Arianti   +9 more
wiley   +1 more source

p53 protein degradation redefines the initiation mechanisms and drives transitional mutations in colorectal cancer

Nature Communications
Incidence of colorectal cancer (CRC) is increasing likely due to different mechanisms driving initiation and progression. The initial model proposed by Fearon and Vogelstein posits it as a multi-hit neoplasia, originating from adenomatous-polyps induced ...
Irene Herranz-Montoya, Mariana Angulo-Aguado, Cristian Perna, Sladjana Zagorac, Luis García-Jimeno, Solip Park, Nabil Djouder   +6 more
doaj   +1 more source

Cold exposure reinstates NAD+ levels and attenuates hepatocellular carcinoma

Cell Stress
Cold exposure has been historically used for medicinal purposes, but its benefits and associated mechanisms in mammalian organisms still remain unclear.
Tatiana P Grazioso, Maria del Mar Rigual, Cristian Perna, Eduardo J Caleiras, Nabil Djouder   +4 more
doaj   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Structural characteristics, antioxidant and immunological activities of polysaccharides from Ficus hirta Vahl based on different extraction methods

Industrial Crops and Products
Ficus hirta Vahl is a bioactive medicinal plant. However, the structural and functional differences of polysaccharides obtained through various extraction methods remain poorly understood, highlighting the need for further research to explore its ...
Ting Ju, Yishu Yin, Heqi Gao, Jiayu Wang, Guanjun Ye, Jiangfei Li, Yingchun Zhang, Fangjing Miao, Weihong Lu   +8 more
doaj   +1 more source

The human gut microbiome across the life course

FEBS Letters, EarlyView.
Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero, Basak Bahcivanci, Antonietta Hayhoe, Animesh Acharjee, Ezgi Özkurt   +4 more
wiley   +1 more source

Concerns with the Study on Australian and New Zealand Fish Oil Products by Nichols et al. (Nutrients 2016, 8, 703) [PDF]

, 2017
We read with interest a study recently published in Nutrients by Nichols et al. [1], which reported that fish oil products available in Australasia are not oxidised and are accurately labelled for content.[...
José Derraik, Wayne Cutfield, David Cameron-Smith, Behrensdorf Derraik, Jose, Cameron-Smith, David, Garg, ML, Cutfield, Wayne, Albert, Benjamin, Manohar Garg, Benjamin Albert   +9 more
core   +1 more source

A novel hepatocyte ketone production assay to help the selection of nutrients for the ketogenic diet treatment of epilepsy

Scientific Reports
The classic ketogenic diet is an effective treatment option for drug-resistant epilepsy, but its high fat content challenges patient compliance. Optimizing liver ketone production guided by a method comparing substrates for their ketogenic potential may ...
Hester Meeusen, Alessia Romagnolo, Sophie A. C. Holsink, Thijs J. M. van den Broek, Ardy van Helvoort, Jan A. Gorter, Erwin A. van Vliet, J. Martin Verkuyl, Jose P. Silva, Eleonora Aronica   +9 more
doaj   +1 more source

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

FEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto, Masatomo So, Ayako Furukawa, Kenji Sugase   +3 more
wiley   +1 more source