Results 91 to 100 of about 3,590 (205)
Abstract Introduction An ethics‐guided decision‐making framework was developed for applying pathology‐supported genetic testing, a multifaceted pharmacodiagnostic approach that translates population risk stratification into clinical utility. We introduce this service, supported by the Open Genome Project, which aligns with the beneficence principle in ...
Manie De Klerk +6 more
wiley +1 more source
Nutrigenetics and Dyslipidemia [PDF]
Dyslipidemia is an abnormal amount of lipids (abnormality in any of the lipoprotein fractions), especially elevated Low Density Lipoprotein (LDLs) and decreased High Density Lipoprotein (HDLs) in the blood (Shalileh et al., 2009). In developed countries, most dyslipidemias are hyperlipidemias; that is, an elevation of lipids in the blood, are often due
openaire +2 more sources
Novel polymorphisms in the 5′UTR of FASN, GPAM, MC4R and PLIN1 ovine candidate genes: Relationship with gene expression and diet [PDF]
We have analyzed the 5′cis-regulatory regions of four genes coding for key proteins involved in lipid metabolism and energy homeostasis in Rasa Aragonesa, Assaf and Roja Mallorquina sheep breeds.
Calvo Lacosta, Jorge Hugo +6 more
core +2 more sources
Background Significant associations between visceral fat and alterations in plasma fatty acids have been identified in overweight individuals. However, there are scant data regarding the relationships of the visceral fat area (VFA) with the plasma fatty ...
Young Ju Lee +7 more
doaj +1 more source
Meta-analysis of genes in commercially available nutrigenomic tests denotes lack of association with dietary intake and nutrient-related pathologies [PDF]
Nutrigenomics is an emerging discipline that aims to investigate how individual genetic composition correlates with dietary intake, as well as how nutrition influences gene expression.
Angeliki Balasopoulou +8 more
core +1 more source
Resveratrol as an Inhibitor of Pregnane X Receptor (PXR): Another Lesson in PXR Antagonism
.: The pregnane X receptor (PXR) plays a central role in the regulation of metabolism. Only few PXR antagonists have been described and the mechanism of PXR inhibition is mostly hypothetical or believed to be allosteric.
Tomas Smutny, Petr Pavek
doaj +1 more source
Clinical metabolomics and nutrition: the new frontier in neonatology and pediatrics. [PDF]
In the pediatric clinic, nutritional research is focusing more and more on preventing the development of long-term diseases as well as supporting the repair processes important in the therapy of already fully developed diseases.
CESARE MARINCOLA, FLAMINIA +4 more
core +1 more source
Nutrigenomics: where are we with genetic and epigenetic markers for disposition and susceptibility? [PDF]
The revelation of the human genome has enabled scientists to assess the disposition and response of an organism to an environmental stimulus; transcriptomics, proteomics, and metabonomics can each generate such holistic views.
Krause, Lutz +2 more
core
Study of sardine oil antioxidant properties for the development of topical therapeutic formulations [PDF]
Sardine is one of the most common fish of the Portuguese coast with important nutritional features. Sardine oil is also a natural source of nutrients with proven benefits for human health, being rich in omega-3 fatty acids, particularly EPA and DHA ...
Bandarra, N. M. +8 more
core +1 more source
This article analyses shifts in metaphors in direct-to-consumer genetic testing, analyzing the websites and select media coverage of the nutrigenetic testing company Sciona (2000–2009) and the personal genome service 23andMe (2006–).
Paula Saukko
doaj +1 more source

