Mitochondria‐associated membranes (MAMs) are contact sites between the endoplasmic reticulum and mitochondria that regulate calcium signaling, lipid metabolism, autophagy, and stress responses. This review outlines their molecular organization, roles in cellular homeostasis, and how dysfunction drives neurodegeneration, metabolic disease, cancer, and ...
Viet Bui+3 more
wiley +1 more source
Production of antibacterial compounds by a Steely hybrid polyketide synthase in Dictyostelium
By selecting appropriate production species under optimised culture conditions, new chlorinated dibenzofuran compounds, which previously could not be analysed in sufficient quantities, were identified from cellular slime mould fruiting bodies. The strong antibacterial activity exhibited by these compounds suggests a link to the ecological function of ...
Tomoaki R. Yamashita+3 more
wiley +1 more source
What Opportunities Exist for Making the Food Supply Nutrition Friendly? A Policy Space Analysis in Mexico [PDF]
Gloria Cervantes+4 more
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The relationship between anabolic and catabolic processes governing lung cancer cell growth is nuanced. We show that ATG4B, an autophagy regulator, is elevated in lung cancer and that high ATG4B is associated with worse patient outcomes. Targeting ATG4B in cells reduces growth, protein synthesis, and mTORC1 activity, demonstrating a new relationship ...
Patrick J. Ryan+6 more
wiley +1 more source
Food consumption patterns of adolescents aged 14–16 years in Kolkata, India
Background The nutrition transition has brought about rapid changes in the structure of the Indian diet. The replacement of traditional home-cooked meals with ready-to-eat, processed foods has contributed to an increased risk of chronic diseases in urban
Neha Rathi+2 more
doaj +1 more source
A New Method to Monitor the Nutritional Quality of Packaged Foods in the Global Food Supply in Order to Provide Feasible Targets for Reformulation [PDF]
Fabienne Leroy+6 more
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Excess Ca2+ ions activate the Calcium‐Sensing Receptor (CaSR), which subsequently drives the uptake of excess inorganic phosphate (Pi) via the Pi transporter (Pit−1) in chondrocytes. This mechanism causes a toxic increase in intracellular Pi concentration, ultimately leading to chondrocyte apoptosis and pathological mineralization. Excess extracellular
Sachie Nakatani+7 more
wiley +1 more source
Report of the Scientific Committee of the Spanish Agency for Food Safety and Nutrition (AESAN) on the equivalence between the disinfection of tools in slaughterhouses and cutting rooms with hot water supplied at a temperature not less than 82 ºC, and various alternative systems of disinfection [PDF]
AESAN Scientific Committee
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Abstract The gut microbiota plays a pivotal role in maintaining host metabolic homeostasis and overall physiological functions. Shenling Baizhu San (SLBZS), a time‐honored classical prescription for tonifying Qi, strengthening the spleen, removing dampness, and arresting diarrhea, has shown broad clinical efficacy in digestive disorders.
Jinlan Di, Xiaochun Zhang
wiley +1 more source
Nutrition-sensitive climate risk across food production systems
Global nutrition targets remain unmet, as over half of preschool-aged children and two-thirds of non-pregnant women of reproductive age worldwide suffer from micronutrient deficiencies.
Michelle Tigchelaar+11 more
doaj +1 more source