Results 61 to 70 of about 140,820 (303)

Targeting the MDM2‐MDM4 interaction interface reveals an otherwise therapeutically active wild‐type p53 in colorectal cancer

open access: yesMolecular Oncology, EarlyView.
This study investigates an alternative approach to reactivating the oncosuppressor p53 in cancer. A short peptide targeting the association of the two p53 inhibitors, MDM2 and MDM4, induces an otherwise therapeutically active p53 with unique features that promote cell death and potentially reduce toxicity towards proliferating nontumor cells.
Sonia Valentini   +10 more
wiley   +1 more source

Consumer Acceptance of Novel Breads Containing Vitamin D and Soy Given Three Different Nutrition Information Conditions [PDF]

open access: yes, 2015
Functional foods are an innovative area of food science that improve the health of consumers through the use of synergistic ingredients. A Vitamin D bread with soy was developed by scientists at the Ohio State University and is poised to reduce the ...
De Guire, Ruth
core  

How Do Consumers Use Nutrition Labels on Food Products in the United States? [PDF]

open access: yes, 2017
This study examined how consumers use food labels in the United States. Based on the results from the cluster analysis, eight nutrition label questions from the Health and Diet Survey fell into 2 categories of label usage: for shopping or for dietary ...
Andrews, J. Craig   +4 more
core   +2 more sources

The critical role of DNA damage‐inducible transcript 4 (DDIT4) in stemness character of leukemia cells and leukemia initiation

open access: yesMolecular Oncology, EarlyView.
Stemness properties, including quiescence, self‐renewal, and chemoresistance, are closely associated with leukemia relapse. Here, we demonstrate that DNA damage‐inducible transcript 4 (DDIT4) is induced in the hypoxic bone marrow niche and is essential for maintaining the stemness of AML1‐ETO9a leukemia cells.
Yishuang Li   +12 more
wiley   +1 more source

Pengetahuan Nutrition Facts dan Pemilihan Makanan Kemasan Mahasiswa Obesitas antara Metode Edukasi Personal dan Ceramah

open access: yesAmerta Nutrition, 2018
Background: The incidence of obesity increases regardless of age. It may happen because these students like to consume snacks/ packaged foods and rarely pay attention to the contents of Nutrition Facts label.
Ismi Ningtyas   +2 more
doaj   +1 more source

Understanding and measuring mechanical signals in the tumor stroma

open access: yesFEBS Open Bio, EarlyView.
This review discusses cancer‐associated fibroblast subtypes and their functions, particularly in relation to extracellular matrix production, as well as the development of 3D models to study tumor stroma mechanics in vitro. Several quantitative techniques to measure tissue mechanical properties are also described, to emphasize the diagnostic and ...
Fàtima de la Jara Ortiz   +3 more
wiley   +1 more source

TAMANHO DA PORÇÃO E GORDURA TRANS: OS RÓTULOS DE ALIMENTOS INDUSTRIALIZADOS BRASILEIROS ESTÃO ADEQUADOS?

open access: yesDemetra, 2015
Objective: To associate serving size and trans fat on the nutrition facts label of packaged foods commercialized in a Brazilian supermarket. Methods: The serving size was categorized according to the Brazilian law and the trans fat occurrence was ...
Nathalie Kliemann   +4 more
doaj   +1 more source

Fourth-grade nutrition education newsletter : lesson 4 [PDF]

open access: yes, 2016
The Nutrition facts label give us information about servings, calories, fat, fiber, sodium and some vitamins and minerals. Ingredients are listed by weight.

core  

Long non‐coding RNAs as therapeutic targets in head and neck squamous cell carcinoma and clinical application

open access: yesFEBS Open Bio, EarlyView.
Long non‐coding RNAs (lncRNAs) occupy an abundant fraction of the eukaryotic transcriptome and an emerging area in cancer research. Regulation by lncRNAs is based on their subcellular localization in HNSCC. This cartoon shows the various functions of lncRNAs in HNSCC discussed in this review.
Ellen T. Tran   +3 more
wiley   +1 more source

Knockout of the mitoribosome rescue factors Ict1 or Mtrfr is viable in zebrafish but not mice: compensatory mechanisms underlying each factor's loss

open access: yesFEBS Open Bio, EarlyView.
Mitochondria contain two mitoribosome rescue factors, ICT1 and MTRFR (C12orf65). ICT1 also functions as a mitoribosomal protein in mice and humans, and its loss is lethal. Although Mtrfr knockout mice could not be generated, knockout zebrafish lines for ict1 and mtrfr were established.
Nobukazu Nameki   +11 more
wiley   +1 more source

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