Results 41 to 50 of about 413,630 (215)
Jacksaint Saintila,1 Yaquelin E Calizaya-Milla,2 Sergio E Calizaya-Milla,2 Ashly A Elejabo-Pacheco,2 Genesis A Sandoval-Valentin,2 Shirley G Rodriguez-Panta2 1Medical School, Señor De Sipán University, Chiclayo, Peru; 2Research Group for Nutrition and ...
Saintila J +5 more
doaj
The cytoskeleton‐mediated transport of mitochondria via tunnelling nanotubes restores respiration, increases ATP production, rescues cells from apoptosis, activates the AKT/mTOR signalling pathway, promotes cell migration and invasiveness, contributes to cancer progression and treatment resistance.
Stanislava Martínková, Jan Trnka
wiley +1 more source
Evaluating the effect of γ‐oryzanol on MASLD pathology using a medaka fish model
This study explores a liver disease called MASLD, which is increasing worldwide and can lead to serious damage. Researchers used medaka fish instead of rodents to test a food compound, γ‐oryzanol. Fish fed this compound had less liver fat and healthier gut bacteria.
Yukako Ito +7 more
wiley +1 more source
Background A composite evaluation that merges various data quality indicators separately enabled the researchers to score the overall data quality of the research. In this context, the objective of the present study is to develop composite anthropometric
Rafaela Oliveira-Santos +7 more
doaj +1 more source
Epigenetic Dysregulation and Cancer Progression: How Epigenetic Modifications Shape Tumor Fate
Epigenetic modifications, including DNA methylation, histone modification, and non-coding RNAs, play crucial roles in regulating gene expression without altering the underlying DNA sequence.
Farzand Farhad Hamid Hamid
doaj +1 more source
Biophysical characterisation shows that NanX, a membrane transport protein from the major facilitator superfamily (MFS), forms both monomers and dimers after purification. AlphaFold modelling and substrate docking provide information on residues likely involved in substrate recognition for NanX and another MFS member, NanT.
Michael C. Newton‐Vesty +13 more
wiley +1 more source
The C‐terminal domain of yeast Arginyltransferase1 is essential for its catalytic activity
Arginyltransferase 1 (Ate1), a eukaryotic enzyme, catalyses arginylation, transferring arginine from tRNA‐Arg to the amino terminus of the target protein. Overexpression of Ate1 in yeast is lethal and is dependent on arginylation. This study elucidates how mutations in the cofactor‐binding and active site of Ate1 and truncation of its structural ...
Vikas Kumar Yadav +4 more
wiley +1 more source
ABSTRACT Objective To characterize the demographic, clinical, and laboratory features of the Chinese patients of genetic Creutzfeldt‐Jakob disease with T188K variant (T188K‐gCJD), the most common subtype of genetic prion diseases (gPrDs) in China. Methods In this nationwide retrospective study, data from 98 genetically confirmed T188K‐gCJD patients ...
Chun‐Jie Li +11 more
wiley +1 more source
Data‐Driven SuStaIn Model of Disability Progression in Amyotrophic Lateral Sclerosis
ABSTRACT Objective To determine whether ordinal Subtype and Stage Inference (SuStaIn) applied to routine ALSFRS‐R item scores can identify reproducible disability progression patterns in amyotrophic lateral sclerosis (ALS) and provide clinically meaningful staging.
Giammarco Milella +5 more
wiley +1 more source
Integrating nutritional value into Life Cycle Assessment (LCA) is essential for developing food system policies and interventions that simultaneously address environmental sustainability and human health.
Graham A. McAuliffe +5 more
doaj +1 more source

