Results 51 to 60 of about 150,942 (311)
BackgroundThere are various cross-sectional studies that concluded that vitamin D is associated with blood pressure, but randomized controlled studies have not yielded consistent conclusions.
Jinhang Che +7 more
doaj +1 more source
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
Medical Examination in Nutrition Surveys [PDF]
Pellagra was the most important deficiency disease used as a model for nutrition surveys, because its diagnosis depended on physical signs. By the mid twentieth century, laboratory tests improved the specificity of physical signs in diagnosis of deficiency disease. The author uses his experience in Panama to illustrate how attention to the details of a
openaire +2 more sources
The ubiquitin ligase RNF115 is required for the clearance of damaged lysosomes
Upon lysosomal rupture, an E3 ubiquitin ligase RNF115 translocates from the cytosol to the damaged lysosomal membrane. Moreover, RNF115 depletion impairs the clearance of damaged lysosomes, identifying it as a key regulator of lysosomal quality control.
Sae Nakanaga +3 more
wiley +1 more source
pH‐mediated activation of the lysosomal arginine sensor SLC38A9
Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley +1 more source
Machine learning-based prediction of vitamin D deficiency: NHANES 2001-2018
BackgroundVitamin D deficiency is strongly associated with the development of several diseases. In the current context of a global pandemic of vitamin D deficiency, it is critical to identify people at high risk of vitamin D deficiency.
Jiale Guo, Qionghan He, Yehai Li
doaj +1 more source
Plan and operations of the 10th Korea National Health and Nutrition Examination Survey (2025–2027) [PDF]
The Korea National Health and Nutrition Examination Survey (KNHANES) is a national health survey mandated by Article 16 of the National Health Promotion Act to assess the health and nutritional status of the Korean population.
Sun-Ja Kim +7 more
doaj +1 more source
Background: Knowledge about the nutrient intakes and food consumption in the Nordic and Baltic countries is important for the formulation of dietary reference values (DRVs) and food-based dietary guidelines (FBDGs), as part of the Nordic Nutrition ...
Warensjö Lemming, Eva, +4 more
core +1 more source
The ubiquitin‐proteasome system and autophagy as guardians of the cellular proteome
This Perspective covers the three principles governing the crosstalk between the ubiquitin‐proteasome system and autophagy in cellular proteostasis: (1) a shared ubiquitin code routing substrates via shuttle factors or autophagy receptors; (2) spatial compartmentalization into phase‐separated degradation hubs and organelle‐specific modules (exemplified
Ivan Dikic
wiley +1 more source
Background: Food insecurity has attracted the attention of people, experts, and policymakers as a major public health problem over the past two decades. The aim of this study was to determine the prevalence of food insecurity among children aged 6 to 59 ...
Hanieh Ghasemzadeh +4 more
doaj

