Results 61 to 70 of about 416,294 (361)

Remaining Challenges in Tanzania's Efforts to Eliminate Iodine Deficiency. [PDF]

, 2007
To determine iodine levels in salt and iodine deficiency prevalence in school-aged children in 16 districts in Tanzania with previous severe iodine deficiency. A cross-sectional study in schoolchildren.
Aghini-Lombardi, Alfred Sanga, Andersson, Celestin Mgoba, Chauhan, Delange, Dunn, Godwin D Ndossi, Haldimann, Jianqun, Kavishe, l'Ons, Mannar, Nicholaus Mlingi, Perez, Peterson, Pichard, Pino, Sebotsa, Stefan Peterson, Ted Greiner, van de Haar, Vincent D Assey, Zhao   +23 more
core   +4 more sources

A survey on AI nutrition recommender systems [PDF]

Proceedings of the 12th ACM International Conference on PErvasive Technologies Related to Assistive Environments, 2019
The goal of this work is to provide an overview of existing approaches regarding AI nutrition recommender systems. A breakdown of such systems into task-specific components is presented, as well as methodologies concerned with each individual component.
Theodoridis, Thomas, Solachidis, Vassilios, Dimitropoulos, Kosmas, Gymnopoulos, Lazaros, Daras, Petros   +4 more
openaire   +1 more source

Molecular imaging predicts trastuzumab‐deruxtecan (T‐DXd) response in head and neck cancer xenograft models

Molecular Oncology, EarlyView.
Trastuzumab‐deruxtecan, a HER2‐targeting antibody‐drug conjugate, shows promising antitumor activity in head and neck squamous cell carcinoma with low HER2 expression. In vitro and in vivo studies demonstrated dose‐dependent cell death and tumor growth reduction in low HER2‐expressing cell lines, which correlated with drug accumulation measured using a
Abdullah Bin Naveed, Lucas Mani, Muhammad Bilal Mirza, Ashtyn McAdoo, Takahito Kondo, Hidenori Tanaka, Nicole Meeks, Eben Rosenthal, Marisa Hom   +8 more
wiley   +1 more source

Chimeric diphtheria toxin–CCL8 cytotoxic peptide for breast cancer management

Molecular Oncology, EarlyView.
DTCCL8 is a recombinant fusion toxin that targets cancer cells expressing chemokine receptors. By combining diphtheria toxin with CCL8, DTCCL8 binds to multiple receptors on tumor cells and induces selective cytotoxicity. This strategy enables receptor‐mediated targeting of cancer and may support the development of chemokine‐guided therapeutics ...
Bernardo Chavez, Asieh Naderi, Kim‐Tuyen Huynh‐Dam, Vitali Sikirzhytski, Ioulia Chatzistamou, Hippokratis Kiaris   +5 more
wiley   +1 more source

Targeting carbonic anhydrase IX/XII prevents the anti‐ferroptotic effect of stromal lactic acid in prostate carcinoma

Molecular Oncology, EarlyView.
In prostate carcinoma, lactic acid, secreted by highly glycolytic cancer‐associated fibroblasts, is imported into tumor cells through the MCT1 transporter and prevents RSL3 and erastin‐induced ferroptosis (A). Targeting of carbonic anhydrase IX/XII, the main extracellular pH regulators, in tumor and stromal cells reduces microenvironmental acidosis and
Elisa Pardella, Giuseppina Comito, Luigi Ippolito, Erica Pranzini, Marta Iozzo, Giulia Gangarossa, Francesca Virgilio, Silvia Bua, Alessio Nocentini, Giada Sandrini, Nicla Lorito, Marina Bacci, Gabriella Nesi, Pietro Spatafora, Sergio Serni, Claudiu T. Supuran, Andrea Morandi, Paola Chiarugi, Elisa Giannoni   +18 more
wiley   +1 more source

The critical role of DNA damage‐inducible transcript 4 (DDIT4) in stemness character of leukemia cells and leukemia initiation

Molecular Oncology, EarlyView.
Stemness properties, including quiescence, self‐renewal, and chemoresistance, are closely associated with leukemia relapse. Here, we demonstrate that DNA damage‐inducible transcript 4 (DDIT4) is induced in the hypoxic bone marrow niche and is essential for maintaining the stemness of AML1‐ETO9a leukemia cells.
Yishuang Li, Zhijie Cao, Haiyan Xing, Zhenya Xue, Wenbing Liu, Jiayuan Chen, Yihan Mei, Runxia Gu, Hui Wei, Shaowei Qiu, Min Wang, Qing Rao, Jianxiang Wang   +12 more
wiley   +1 more source

Targeting of PTP4A3 overexpression sensitises HGSOC cells towards chemotherapeutic drugs

Molecular Oncology, EarlyView.
In HGSOC with normal KRAS expression, high PTP4A3 expression regulates autophagy activation. Conversely, in HGSOC with high KRAS expression, KRAS dictates autophagy control, and PTP4A3 is not required. When high PTP4A3 expression is inhibited, HGSOC cells are preferentially sensitised towards DNA‐damaging agents.
Ana López‐Garza, David James, Emma Creagh, James T. Murray   +3 more
wiley   +1 more source

Does geographic targeting of nutrition interventions make sense in cities? [PDF]

Although most developing country cities are characterized by pockets of substandard housing and inadequate service provision, it is not known to what degree low incomes and malnutrition are confined to specific neighborhoods.
Armar-Klemesu, Margaret, Levin, Carol E., Maxwell, Daniel G., Morris, Saul Sutkover, Ruel, Marie T.   +4 more
core  

A holistic approach to enhance the use of neglected and underutilized species: the case of Andean grains in Bolivia and Peru [PDF]

, 2014
The IFAD-NUS project, implemented over the course of a decade in two phases, represents the first UN-supported global effort on neglected and underutilized species (NUS).
Amaya, K., Gotor, E., Jager, M., Padulosi, S., Rojas, W., Valdivia, R.O.   +5 more
core   +2 more sources

Medical Examination in Nutrition Surveys [PDF]

The Journal of Nutrition, 2005
Pellagra was the most important deficiency disease used as a model for nutrition surveys, because its diagnosis depended on physical signs. By the mid twentieth century, laboratory tests improved the specificity of physical signs in diagnosis of deficiency disease. The author uses his experience in Panama to illustrate how attention to the details of a
openaire   +3 more sources