Results 81 to 90 of about 1,922,259 (313)

Autophagy and mitophagy in pancreatic β‐cell homeostasis and their involvement in diabetes pathophysiology

FEBS Letters, EarlyView.
This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee, Mingming Tong, Anna L. Gloyn   +2 more
wiley   +1 more source

Survey of Nutritional Status and Food Security in Children Aged 6 to 59 Months and Its Relationship with Some Socioeconomic Factors of Households in Mehdiabad Neighborhood of Shiraz, Iran, in 2018

تحقیقات نظام سلامت, 2022
Background: Food insecurity has attracted the attention of people, experts, and policymakers as a major public health problem over the past two decades. The aim of this study was to determine the prevalence of food insecurity among children aged 6 to 59 ...
Hanieh Ghasemzadeh, Sepideh Dolati, Alemeh Hariri-Far, Zahra Mollarasouli, Ali Barzegar   +4 more
doaj  

Partial depletion of plasminogen activator inhibitor‐1 decreases subcutaneous fat cell hypertrophy and liver cholesterol in high‐fat‐fed female mice

FEBS Letters, EarlyView.
Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante, Robert Sharp, Pradip K. Saha, Elizabeth S. Anaya, Elizabeth L. Lieu, Evelyn L. de Groot, Pooja Patel, Mi Jeong Heo, Aaron R. Cox, Kang Ho Kim, Sean M. Hartig   +10 more
wiley   +1 more source

Northern Territory market basket survey 2011

, 2011
In 1995 the NT Department of Health and Community Services developed the NT Food and Nutrition Policy. One of the strategies identified in this policy was to develop a tool (the ?Market Basket Survey?) to monitor food cost, availability, variety and ...
Nutrition and Physical Activity Program
core  

Translophagy—A potential link between autophagy impairment and translational errors

FEBS Letters, EarlyView.
Neurodegenerative diseases are characterised by the accumulation of abnormal proteins and protein aggregates, but their origin often remains unknown. We propose that selective autophagy removes damaged protein‐making machinery, preventing errors during protein synthesis.
Mykola V. Korolchuk, Gailing Ma, Robin Antrobus, Diego Manni, Marco Trevisan‐Herraz, Mustafa Khwaja, Max Brown, Gavin D. Richardson, Masaaki Komatsu, Daniel Erskine, Viktor I. Korolchuk, Tetsushi Kataura   +11 more
wiley   +1 more source

The heterodimeric amino acid transporters (HAT) of the SLC7/SLC3 family: A structure−function relationships and relevance to human pathology

FEBS Letters, EarlyView.
Heterodimeric amino acid transporters consist of SLC7 and SLC3 family proteins arranged in a conserved structural organization. They regulate nutrient transport across cell membranes, supporting essential cellular functions. These transporters also contribute to xenobiotic/drug uptake and distribution.
Mariafrancesca Scalise, Tiziano Mazza, Raffaella Scanga, Lara Console, Michele Galluccio, Cesare Indiveri   +5 more
wiley   +1 more source

Metastatic niche shaped by host factors influences disseminated cancer cell fate

FEBS Letters, EarlyView.
Metastasis is shaped not only by cancer cells but also by the environments they encounter. This review explores how factors such as aging, diet, the microbiome, lifestyle, and environmental exposures remodel organ‐specific niches in the lung, liver, bone, and brain, influencing where metastatic cells survive, remain dormant, or grow, and ultimately ...
Gwennan Delyth Ward, Álvaro Ruiz‐Tabas, Patricia Altea‐Manzano   +2 more
wiley   +1 more source

Malaita [cartographic material] : 1:50,000 sketch map.

, 1967
Ed. 1, 1967. Map series of the Solomon Islands, showing habours, schools, rivers, islands, cities, and mountains. Relief shown by hachures.; Each sheet is numbered and named individually.; "Printed for Directorate of Overseas Surveys by the Ordnance ...
Great Britain. Directorate of Overseas Surveys.
core  

Smaller is better: nanobodies meet NMR

FEBS Letters, EarlyView.
Nanobodies are single‐domain antigen‐binding fragments derived from camelid heavy chain antibodies. Their small size, high stability, and exceptional specificity make nanobodies uniquely useful probes for NMR studies of protein dynamics, transient conformational states, and protein–protein interactions.
Oleg Y. Dmitriev
wiley   +1 more source

Metabolomics and human nutrition [PDF]

, 2011
The present report summarises a workshop convened by the UK Food Standards Agency (Agency) on 25 March 2010 to discuss the current Agency's funded research on the use of metabolomics technologies in human nutrition research.
Mathers, John, Sandy Primrose, Kirkpatrick, Verity, Chris Seal, Primrose, Sandy, Beckmann, Manfred, Draper, John, John H. Beattie, Elsom, Rachel, John Draper, Sumanto Haldar, Seal, Chris, Augustin Scalbert, Beattie, John, Jenab, Mazda, Keun, Hector, Hector Keun, Rachel Elsom, Haldar, Sumanto, John K. Lodge, Manfred Beckmann, Scalbert, Augustin, Lodge, John, Verity Kirkpatrick, John C. Mathers, Mazda Jenab   +25 more
core   +1 more source