Hypothalamic Control of Liver Health and Disease: From Circuits to Pathophysiology and Therapies
This review delineates the hypothalamic circuits that control liver homeostasis via autonomic and neuroendocrine pathways. Dysregulation of this hypothalamus–liver axis drives disease progression across a spectrum including steatotic liver disease, liver inflammation and injury, fibrosis, cirrhosis, and hepatocellular carcinoma.
Qin Tang +7 more
wiley +1 more source
Obesity Hypoventilation Syndrome (OHS) as A Chronic Inflammatory Disease: A Clinical Case. [PDF]
Zarghi S +4 more
europepmc +1 more source
Super‐multiplexed Label‐free Raman Imaging (SLRI) enables 2D/3D metabolic mapping of intact Drosophila testes. Moving beyond descriptive morphology, it establishes a multidimensional tool for tissue metabolic remodeling, and offers a generalizable platform for complex tissue analysis, with implications extending to development and disease. ABSTRACT The
Jiaxin Li +23 more
wiley +1 more source
Effect of percutaneous acupoint electrical stimulation combined with nutritional support on gastrointestinal function and nutritional status of patients after unicondylar knee arthroplasty. [PDF]
Liu J +5 more
europepmc +1 more source
Our study identifies an Hnf4a‐driven super‐enhancer of hepatic Ahcy that mediates the protective effects of intermittent fasting against MASLD. Disruption of the Ahcy super‐enhancer reduces Ahcy expression and exacerbates lipid accumulation. This pathway prevents aberrant promoter hypermethylation by maintaining the SAM/SAH balance, as exemplified by ...
Huafeng Chen +6 more
wiley +1 more source
Low 25(OH)Vitamin D levels are associated with nutritional risk and disease severity in outpatient individuals with advanced chronic liver disease. [PDF]
Albuquerque JMDC +6 more
europepmc +1 more source
Nutritional Status, Body Composition, and Frailty in Community-Dwelling and Institutionalized Albanian Older Adults: A Cross-Sectional Study. [PDF]
Gjergji S +6 more
europepmc +1 more source
Impact of Nutritional and Organoleptic Use of Underutilized Green Leafy Vegetables in Bakery Products: A Systematic Review of Novel Food Applications. [PDF]
Santhanam M +8 more
europepmc +1 more source

