Results 151 to 160 of about 3,991,247 (327)

Homeostasis of Gut Microbiota Protects against Susceptibility to Fungal Pneumonia

open access: yesAdvanced Science, EarlyView.
Fungal pneumonia induces inflammation, shown by heightened IL‐6, IL‐1β, TNF‐α levels and a growth in Staphylococcus in the alveolar flora. The gut microbiota, acting through the gut‐lung axis via blood, impacts fungal pneumonia susceptibility by altering lung metabolism and inflammatory responses.
Jian Ji   +12 more
wiley   +1 more source

Nucleotides as an Anti‐Aging Supplementation in Older Adults: A Randomized Controlled Trial (TALENTs study)

open access: yesAdvanced Science, EarlyView.
The TALENTs randomized controlled trial evaluates the potential of nucleotides supplementation as an anti‐aging intervention in older adults. After 19 weeks, nucleotides supplementation significantly reduces DNA methylation age, suggesting a delay in epigenetic aging, and improves insulin sensitivity without severe adverse events.
Shuyue Wang   +9 more
wiley   +1 more source

Lactate‐Activated GPR132‐Src Signal Induces Macrophage Senescence and Aggravates Atherosclerosis Under Diabetes

open access: yesAdvanced Science, EarlyView.
Elevated lactate in diabetes activates the GPR132‐Src pathway in macrophages, inducing macrophage senescence and further enhancing foam cell formation. This mechanism exacerbates atherosclerotic progression. Abstract Diabetes is widely acknowledged as a significant risk factor for atherosclerosis, facilitating plaque formation through various ...
Xiaofeng Ge   +10 more
wiley   +1 more source

Meta-analysis of spineless cactus feeding to meat lambs: performance and development of mathematical models to predict dry matter intake and average daily gain

open access: yesAnimal, 2019
Spineless cactus is a useful feed for various animal species in arid and semiarid regions due to its adaptability to dry and harsh soil, high efficiency of water use and carbohydrates storage.
L.S. Knupp   +9 more
doaj  

Protein Requirements of Infants: 3. The Nutrition of Premature Infants

open access: green, 1950
W. F. Young   +4 more
openalex   +1 more source

Novel Antimicrobial Protein Fibroblast Growth Factor 8 Accelerates Skin Wound Healing via Directly Inhibiting Bacteria and Activating Glycolysis

open access: yesAdvanced Science, EarlyView.
Wound infections induce gcFGF8a expression, which subsequently executes direct antimicrobial activity to suppress local infection while simultaneously activating the FGFR4‐mediated ERK/AKT‐mTOR signaling cascade, thereby upregulating HIF1α and enhancing glycolysis. These coordinated actions synergistically promote tissue repair by eliminating pathogens
Ya‐Zhen Hu   +6 more
wiley   +1 more source

RELAÇÃO METIONINA E COLINA DIETÉTICA SOBRE O DESEMPENHO DE CODORNAS JAPONESAS (Coturnix coturnix japonica) EM POSTURA

open access: yesCiência Animal Brasileira, 2011
We evaluated the relationship between levels of methionine and choline on the performance of Japanese quails (Coturnix coturnix japonica) at the production stage, using 432 birds at 65 days of age and weighing 155g, in a completely randomized design in ...
Solange de Faria Castro   +5 more
doaj  

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