Results 171 to 180 of about 4,190,261 (351)

A Compound Screen Based on Isogenic hESC‐Derived β Cell Reveals an Inhibitor Targeting ZnT8‐Mediated Zinc Transportation to Protect Pancreatic β Cell from Stress‐Induced Cell Death

open access: yesAdvanced Science, EarlyView.
Pancreatic β cell loss by cellular stress contributes to diabetes pathogenesis. The study demonstrates that WFS1–ZnT8–zinc axis regulates vicious cycle of zinc transportation and cellular stress in pancreatic β cell. Based on that, the study applies a strategy for compound screening targeting ZnT8 based on human models, and identifies anisomycin, as a ...
Rui Hu   +19 more
wiley   +1 more source

The multifactorial aquaculture‐related COVID‐19 shock in Benin, West Africa: A socio‐economic perspective of mitigating the disruptive impacts on the small‐scale and subsistence producers

open access: yesAquaculture, Fish and Fisheries, Volume 2, Issue 6, Page 507-521, December 2022., 2022
Graphical Abstract This study deals with a timely topic, COVID‐19, whose impacts on aquaculture have never been quantified in Benin. Direct discussions were held with aquaculture producers to understand how they are feeling the impact of the pandemic on their business.
Toundji Olivier Amoussou   +7 more
wiley   +1 more source

Revisiting food-sourced vitamins for consumer diet and health needs: a perspective review, from vitamin classification, metabolic functions, absorption, utilization, to balancing nutritional requirements. [PDF]

open access: yesPeerJ, 2021
Ofoedu CE   +17 more
europepmc   +1 more source

NHANES-GCP: Leveraging the Google Cloud Platform and BigQuery ML for reproducible machine learning with data from the National Health and Nutrition Examination Survey [PDF]

open access: yesarXiv
Summary: NHANES, the National Health and Nutrition Examination Survey, is a program of studies led by the Centers for Disease Control and Prevention (CDC) designed to assess the health and nutritional status of adults and children in the United States (U.S.).
arxiv  

Bioinspired Strong and Tough Layered Bulk Composites via Mycelial Interface Anchoring Strategy

open access: yesAdvanced Science, EarlyView.
An interface anchoring strategy, which fixes the interface between the soft and hard phases to immobilize 2D materials, by leveraging the growth of biological living mycelium is proposed. This approach results in the formation of a lightweight and strong composite material (the LBCs) with a layered structure composed of soft and hard phases.
Hao Wang   +6 more
wiley   +1 more source

Fish farming systems diversity and implications in the Republic of Benin: Fish farm types and their economic performance

open access: yesAquaculture, Fish and Fisheries, Volume 2, Issue 6, Page 522-539, December 2022., 2022
Farm type delineation allows for simplifying the diversity in fish farming systems. Multivariate statistical techniques combined with the Calinski and Harabasz pseudo F statistic and bootstrapping were applied to determine the realistic number of fish farm types.
Ygue Patrice Adegbola   +2 more
wiley   +1 more source

GLS1‐Mediated Redundancy in Glutamate Accelerates Arterial Calcification via Activating NMDAR/Ca2+/β‐Catenin Pathway

open access: yesAdvanced Science, EarlyView.
GLS1 is a novel contributor to arterial calcification. GLS1‐catalyzed glutamate exerts the promoting effects on osteogenic reprogramming in arteries. NMDAR, a glutamate receptor, is also activated and overexpressed during arterial calcification.
Ziting Zhou   +18 more
wiley   +1 more source

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