Results 51 to 60 of about 28,837 (280)

Autophagy and mitophagy in pancreatic β‐cell homeostasis and their involvement in diabetes pathophysiology

FEBS Letters, EarlyView.
This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee, Mingming Tong, Anna L. Gloyn   +2 more
wiley   +1 more source

Reasons for nutritional supplements i use by physical activity practioners of Antônio Prado-RS

Revista Brasileira de Nutrição Esportiva, 2021
Objective: To verify the reason for the use of nutritional supplements among gym goers in Antônio Prado-RS. Cross-sectional study evaluating all 222 physical activity practitioners attending the five gyms in the city using nutritional supplements.
Sabrina Susin, Juliana Zortéa, Bruna Nicoletto   +2 more
doaj  

Supplementary Files: A Canadian dairy nutritionist survey to assess current practices in trace element diet formulations

, 2023
Supplementary Materials S1. Dairy cow nutritionist surveySupplementary Materials S2. Description of Canadian dairy nutritionists who responded to the survey Supplementary Materials S3.
Duplessis, M (via Mendeley Data), Duplessis, Mélissa   +1 more
core   +1 more source

Partial depletion of plasminogen activator inhibitor‐1 decreases subcutaneous fat cell hypertrophy and liver cholesterol in high‐fat‐fed female mice

FEBS Letters, EarlyView.
Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante, Robert Sharp, Pradip K. Saha, Elizabeth S. Anaya, Elizabeth L. Lieu, Evelyn L. de Groot, Pooja Patel, Mi Jeong Heo, Aaron R. Cox, Kang Ho Kim, Sean M. Hartig   +10 more
wiley   +1 more source

Pulmonary rehabilitation in COPD – available resources and utilization in Swedish primary and secondary care

International Journal of COPD, 2017
Josefin Sundh,1 Helena Lindgren,2 Mikael Hasselgren,2 Scott Montgomery,3–5 Christer Janson,6 Björn Ställberg,7 Karin Lisspers7 1Department of Respiratory Medicine, School of Medical Sciences, 2Medical Programme, School of Medical ...
Sundh J, Lindgren H, Hasselgren M, Montgomery S, Janson C, Ställberg B, Lisspers K   +6 more
doaj  

Structural and biochemical analysis of a B12 superbinder

FEBS Letters, EarlyView.
BtuG proteins are vitamin B12 scavengers in Bacteroides thetaiotaomicron, a dominant human gut bacterium. We present crystal structures of three BtuG homologs bound to cobalamin and its precursor cobinamide, revealing picomolar binding affinities, among the highest known for any natural protein.
Jose M. Martinez Felices, Jacob J. Whittaker, Dirk J. Slotboom, Albert Guskov   +3 more
wiley   +1 more source

Nutritional aspect for SARS-CoV-2 infection- current perspectives [PDF]

Perspectives In Medical Research, 2020
SARS-CoV-2 pandemic has seeped through the world like never before. The infection count as well as mortality count is increasing day by day. Till now 9 million patients are affected worldwide and mortality count is 4 lakhs[1] .No proven definitive ...
Dr. Manjiri Ranade Mudgalkar
doaj  

The heterodimeric amino acid transporters (HAT) of the SLC7/SLC3 family: A structure−function relationships and relevance to human pathology

FEBS Letters, EarlyView.
Heterodimeric amino acid transporters consist of SLC7 and SLC3 family proteins arranged in a conserved structural organization. They regulate nutrient transport across cell membranes, supporting essential cellular functions. These transporters also contribute to xenobiotic/drug uptake and distribution.
Mariafrancesca Scalise, Tiziano Mazza, Raffaella Scanga, Lara Console, Michele Galluccio, Cesare Indiveri   +5 more
wiley   +1 more source

Hyperosmolar Hyperglycemic Syndrome in a Very Older Patient Treated in Collaboration with Multiple Specialists: A Case Report

Journal of Hospital General Medicine
A 97-year-old woman underwent open repair and immobilization of a right femoral metaphyseal fracture at our hospital. Owing to a postoperative cerebral infarction, enteral nutrition via a nasogastric tube was initiated. The patient subsequently developed
Tomoki Tanie, Miyuki Makino, Kota Ozawa, Yusuke Ito, Kotaro Kanda, Hirotoshi Fujikawa, Koji Oiwa   +6 more
doaj   +1 more source

Metastatic niche shaped by host factors influences disseminated cancer cell fate

FEBS Letters, EarlyView.
Metastasis is shaped not only by cancer cells but also by the environments they encounter. This review explores how factors such as aging, diet, the microbiome, lifestyle, and environmental exposures remodel organ‐specific niches in the lung, liver, bone, and brain, influencing where metastatic cells survive, remain dormant, or grow, and ultimately ...
Gwennan Delyth Ward, Álvaro Ruiz‐Tabas, Patricia Altea‐Manzano   +2 more
wiley   +1 more source