Results 81 to 90 of about 35,176 (268)

Identification of (20R)‐protopanaxadiol from Panax ginseng as a novel anti‐SARS‐CoV‐2 compound

open access: yesFEBS Open Bio, EarlyView.
We established a noninfectious BAC‐based SARS‐CoV‐2 replicon that enables antiviral screening under BSL‐2 conditions. Using this platform, we screened 373 food‐derived compounds and identified (20R)‐protopanaxadiol from Panax ginseng as a novel inhibitor of SARS‐CoV‐2 RNA replication, highlighting the value of safe replicon systems for antiviral ...
Midori Takeda   +4 more
wiley   +1 more source

Effect of a microbial inoculant on fermentation characteristics, aerobic stability, intake, and digestibility of corn silage by rams

open access: yesRevista Colombiana de Ciencias Pecuarias
Summary Background: ensiling of whole-plant corn in tropical environments generally results in poor fermentation, and silages are susceptible to aerobic deterioration resulting in low acceptability by the animals.
Abner A Rodríguez   +3 more
doaj   +1 more source

Australian Lamb Meat – The Response to Societal and Ethnic Influences

open access: yesFood Science of Animal Resources, 2018
Lamb has long been considered a traditional meal within Australia; however as consumer preferences have changed since the 1950’s, consumption of lamb has decreased from the 1980’s.
David Laurence Hopkins   +1 more
doaj   +1 more source

Evolution‐guided yeast complementation reveals functional differences in human PSPH variants

open access: yesFEBS Open Bio, EarlyView.
Ancient genomes can help guide which human genetic variants are tested experimentally. This study applies that idea to PSPH, a gene involved in serine biosynthesis, and uses high‐throughput yeast complementation to compare variant function. The findings reveal measurable differences among selected alleles and illustrate the value of evolution‐guided ...
Mauricio Campa‐Álvarez   +6 more
wiley   +1 more source

EVALUATION OF HERBACEOUS RANGE PLANTS IN EARLY AND LATE RAINY SEASON IN PROTECTED AND OPEN SITES AT BUTANA AREA (ELHWATA) – SUDAN

open access: yesTropical and Subtropical Agroecosystems, 2012
A study was conducted in 2009 to estimate the dry weight yield and nutritive value of grasses and forbs at Butana area. Dry weight of forbs and grasses were higher in late season than in early season.
Ahmed Gofoon Mahala   +2 more
doaj  

Structural studies and functional engineering of NanX: an anhydro‐sialic acid transporter from Escherichia coli

open access: yesFEBS Open Bio, EarlyView.
Biophysical characterisation shows that NanX, a membrane transport protein from the major facilitator superfamily (MFS), forms both monomers and dimers after purification. AlphaFold modelling and substrate docking provide information on residues likely involved in substrate recognition for NanX and another MFS member, NanT.
Michael C. Newton‐Vesty   +13 more
wiley   +1 more source

De novo synthesis of short‐chain aldehydes and hydrocarbons secreted by the brown marmorated stink bug Halyomorpha halys

open access: yesFEBS Open Bio, EarlyView.
The brown marmorated stink bug, Halyomorpha halys, mainly secretes 4‐oxo‐(E)‐2‐hexenal, (E)‐2‐decenal, dodecane and tridecane, a mixture representative of that released by many heteropterans. We demonstrated that H. halys can synthesise these secretory components de novo using dietary glucose.
Haruna Fujimori, Koji Noge
wiley   +1 more source

GelMA‐based 3D spheroids recapitulate transcriptomic and functional hallmarks of myeloid sarcoma

open access: yesFEBS Open Bio, EarlyView.
GelMA 5% hydrogels support the formation of myeloid leukemia spheroids that recapitulate MS‐specific features, including G1 arrest, apoptosis, and ECM‐driven transcriptomic reprogramming. The 3D model mimicked soft‐tissue‐like stiffness and oxygen conditions, and transcriptomic convergence with primary MS samples confirmed its utility as a preclinical ...
Nicolas Germain   +11 more
wiley   +1 more source

Chemical Composition and Nutritve Value of (Astragalus brevidens Freyn & Sint) and (Astragalus masenderanus Bunge)

open access: yesپژوهشهای علوم دامی ایران, 2013
In this study, the nutritive value of AS. brevidens and AS. masenderanus were analyzed in 3 different morphological growth stages (vegetative, flowering, seeding) through chemical composition, in vitro gas production and in vitro dry matter digestibility
F Melati, N Naghdi, R Valizadeh
doaj  

The C‐terminal domain of yeast Arginyltransferase1 is essential for its catalytic activity

open access: yesFEBS Open Bio, EarlyView.
Arginyltransferase 1 (Ate1), a eukaryotic enzyme, catalyses arginylation, transferring arginine from tRNA‐Arg to the amino terminus of the target protein. Overexpression of Ate1 in yeast is lethal and is dependent on arginylation. This study elucidates how mutations in the cofactor‐binding and active site of Ate1 and truncation of its structural ...
Vikas Kumar Yadav   +4 more
wiley   +1 more source

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