Results 61 to 70 of about 33,842 (266)

Targeting transcription factors associated with hemoglobinopathies: Lessons from successful interventions and implications for cancer

Molecular Oncology, EarlyView.
This review summarizes the transcription factors, repressive chromatin‐modifying complexes, and epigenetic mechanisms that control fetal hemoglobin repression. Notably, many regulators of γ‐globin silencing also function in transcriptional and epigenetic networks that drive cancer, highlighting opportunities to translate advances in hemoglobinopathy ...
Meigen Yu, Puspa Das, Xing Zhang, Xiaodong Cheng   +3 more
wiley   +1 more source

Interferon beta drives therapy resistance in a patient‐derived model of high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Interferon type 1 (IFN‐1) production and signaling is associated with the acquisition of therapy resistance, following chronic DNA damage, via Interferon‐related DNA damage resistance signature (IRDS) gene expression. An alternative, DNA damage‐independent role of sustained IFN‐1 mediated resistance was identified and characterized by the emergence of ...
Ashlyn Conant, Tise Suzuki, Kiera McGivney, V. S. S. Abhinav Ayyadevara, Sharon Asariah, Jay Deng, Ethan Nyein, Jacqueline Coats, Gary Yu, Yevgeniya J. Ioffe, Christian Hurtz, Juli J. Unternaehrer   +11 more
wiley   +1 more source

Pharmacological inhibition of the PERK pathway modulates hepatocellular carcinoma growth and immune signaling

FEBS Open Bio, EarlyView.
Pharmacological inhibition of PERK in a DEN‐induced mouse model of liver cancer does not reduce tumor burden but alters cellular stress signaling. Despite blocking PERK activity, downstream stress responses, including CHOP expression, remain active, suggesting compensatory mechanisms within the unfolded protein response that may influence tumor ...
Ada Lerma‐Clavero, Maria Kopsida, Nathalie Arendt, Hans Lennernäs, Markus Sjöblom, Femke Heindryckx   +5 more
wiley   +1 more source

Nutritive value of perennial pastures along an elevation gradient in tropical conditions

Frontiers in Sustainable Food Systems
IntroductionThe nutritive value of forages is one of the main drivers of productivity for livestock. In many tropical regions, same grass species occur at different elevations, but few studies have evaluated nutritive value changes within elevation ...
Luis Villalobos, Claudia Arndt, Rein van der Hoek, Andre M. Mazzetto, Dave Chadwick   +4 more
doaj   +1 more source

Time‐restricted feeding prior to Mycobacterium tuberculosis infection reduces tissue CD4+ T cells with limited impact on bacterial clearance

FEBS Open Bio, EarlyView.
Time‐restricted feeding (TRF) in mice increased liver fatty acid oxidation and decreased fatty acid biosynthesis. These alterations persisted when TRF was discontinued and the host was infected with Mycobacterium tuberculosis. Pre‐exposure to TRF did not alter tissue (lung and spleen) mycobacterial burden but significantly reduced CD3+ T cells in lungs
Ashish Gupta, Nidhi Yadav, Subhasmita Das, R. Rajendra Kumar Reddy, Nupur Sharma, Amol Ratnakar Suryawanshi, Jaswinder Singh Maras, Ranjan Kumar Nanda   +7 more
wiley   +1 more source

Estimation of genetic parameters and selection of Brachiaria humidicola progenies using a selection index

Crop Breeding and Applied Biotechnology, 2012
The objectives of this study were to estimate genetic parameters for agronomic and nutritive value traits for leaves and stems of Brachiaria humidicola progenies and to compare the selection using an additive index considering the agronomic traits alone ...
Ulisses José de Figueiredo, José Airton Rodrigues Nunes, Cacilda Borges do Valle   +2 more
doaj  

Nilai Nutrisi Dadih yang ditambahkan Khamir Asal Dadih

Jurnal Agripet, 2014
(Nutritive value of  dadih added with yeast of dadih origin) ABSTRACT. Dadih is traditionally fermented buffalo milk product which is along with lactic acid bacteria (LAB), a diversity of yeast species involved in fermentation process.
Yurliasni Yurliasni, Yusdar Zakaria, Yunasri Usman   +2 more
doaj   +1 more source

Cyclic azapeptide CD36 ligand attenuates cardiac injury and reduces long‐chain fatty acid accumulation after myocardial ischemia–reperfusion in mice

FEBS Open Bio, EarlyView.
In a murine model of myocardial ischemia and reperfusion (MI/R), the CD36 azapeptide ligand MPE‐298 reduces cardiac injury and transiently lowers left ventricular long‐chain fatty acids (LCFAs) accumulation 3 h after reperfusion, accompanied by a decrease of oxidative stress and inflammation‐associated genes' expression in the heart and adipose tissue.
Jade Gauvin, Naghme Radmannia, David N. Huynh, Liliane Ménard, Caroline Daneault, Maïté Veilleux, Ahsanullah Ahsanullah, André C. Carpentier, William D. Lubell, Matthieu Ruiz, Huy Ong, Sylvie Marleau, Simon‐Pierre Gravel   +12 more
wiley   +1 more source

Chemical characterization of green grain before and after thermal processing in biofortified cowpea cultivars

Revista Ciência Agronômica
The cowpea (Vigna unguiculata (L.) Walp.) is one of the most widely consumed legumes in the North and Northeast of Brazil, representing an important source of protein, energy, fibre and minerals, in addition to generating employment and income.
Natália Quaresma Costa Melo, Regilda Saraiva dos Reis Moreira-Araújo, Marcos Antônio da Mota Araújo, Maurisrael de Moura Rocha   +3 more
doaj   +1 more source

Effects of EM on pH value and nutritive value of feed

浙江大学学报. 农业与生命科学版, 2002
Variations of pH value and nutritive value of EM fermentation feed were researched in this paper. The results are as follows: ①EM can acidulate evidently feed and improve its palatability. ②Nutritive value of feed was raised after fermented by EM.
WANG Xu-ming, NI Yong-zhen, LI Wei-jiong, CHEN Zong-ze, YUAN Yi   +4 more
doaj   +1 more source