Results 41 to 50 of about 33,842 (266)

Cell geometry and membrane protein crowding constrain Escherichia coli growth rate, overflow metabolism, respiration, and maintenance energy

FEBS Letters, EarlyView.
The physical dimensions and shape of bacterial cells define the surface area available to acquire nutrients and the volume available for synthesizing proteins and DNA. Here, we use computational systems biology to decode the importance of cell geometry as a major determinant of prokaryotic phenotype, including growth rate and metabolic efficiency. This
Ross P. Carlson, Tomáš Gedeon, Mauricio Garcia Benitez, Campbell Putnam, William R. Harcombe, Radhakrishnan Mahadevan, Ashley E. Beck   +6 more
wiley   +1 more source

Impact of novel harvest strategies and improved cultivars on alfalfa yield and nutritive value in a Mediterranean environment

Grassland Research
Background The development of alfalfa cultivars with improved digestibility may minimize the yield‐quality tradeoff, enabling higher quality with late‐harvested forage and possibly higher yields.
Sultan Begna, Brenda Perez, Abdelmoneim Z. Mohamed, Katherine Swanson, E. Charles Brummer, Dong Wang, Khaled Bali, Daniel H. Putnam   +7 more
doaj   +1 more source

THE NUTRITIVE VALUE OF BOILED MILK [PDF]

Archives of Pediatrics & Adolescent Medicine, 1916
The experimental work involved in this report is the result of an attempt to determine the comparative nutritive efficiency of milk heated to different temperatures. There is considerable evidence in the literature to the effect that scurvy among infants may be caused by feeding cooked milk exclusively; in fact, this notion is so prevalent that many ...
openaire   +2 more sources

Three phosphatase families form a community: The phosphohydrolases that act upon inositol pyrophosphates

FEBS Letters, EarlyView.
Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
wiley   +1 more source

Modelling stem cell differentiation related processes—A practical overview for biologists

FEBS Letters, EarlyView.
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar, Xinqi Yan, Lucas F. Jansen Klomp, Stefano Schivo, Janine N. Post   +4 more
wiley   +1 more source

Reconstructing enzyme evolution by protein engineering

FEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler, Markus R. Busch, Reinhard Sterner   +2 more
wiley   +1 more source

EVALUACIÓN COMPARATIVA DE LOS ATRIBUTOS NUTRICIONALES Y ANTINUTRICIONALES DE LEGUMINOSAS SUBUTILIZADAS, Canavalia gladiata (JACQ.) DC, Erythrina indica LAM. Y Abrus precatorius L

Tropical and Subtropical Agroecosystems, 2012
Se colectaron muestras de semillas de of Canavalia gladiata, Erythrina indica y Abrus precatorius (roja y negra, semilla de cascara colorada y semilla de cascara blanca) de las regiones de Tamil Nadu y se analizó su composición química con la visión ...
Pious Soris Tresina, Veerabahu ramasamy Mohan   +1 more
doaj  

Decoding the dynamic extracellular matrix in cancer—3D models and bioscaffolds rewire the rules of tumor progression

FEBS Letters, EarlyView.
Cancer progression is regulated by the dynamic matrix code of the tumor microenvironment, which influences cellular behavior and disease development. Importantly, matrix remodeling in three‐dimensional cancer models more accurately reflects in vivo conditions compared to conventional two‐dimensional systems.
Sylvia Mangani, Konstantinos Spanopoulos, Zoi Piperigkou, Nikos K. Karamanos   +3 more
wiley   +1 more source

THE USE OF TRITICALE AS ALTERNATIVE CEREAL GRAIN TO YELLOW CORN IN LAYING HENS DIET [PDF]

Journal of Animal and Poultry Production, 2000
An experiment was conducted to study the nutritional value of triticale grains, using one hundred forty four Mandarah laying hens divided into 4 groups. Four isonitrogenous (16% CP) and isocaloric (2700 Kcal/kg) experimental diets were formulated.
Neven Heneish, A. Abd El-Ghani, F. Aggoor,, T. Tag El-Din   +3 more
doaj   +1 more source

Investigating transcription factor dynamics in health and disease using FRAP

FEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj, Carolina Vazquez Garzon, Jose Joaquin Velasco, Janine N. Post   +3 more
wiley   +1 more source