Results 91 to 100 of about 6,171 (293)

Microglia‐Targeted Biomimetic Tetrahedral Framework Nucleic Acid Nanovesicles for Synergistic Treatment of Sepsis‐Associated Encephalopathy

Advanced Science, EarlyView.
Sepsis‐associated encephalopathy (SAE) lacks effective therapies. We developed ME@FDsi, a biomimetic nanodrug using a tetrahedral framework nucleic acid to deliver disulfiram and siTNFα. It crosses the blood‐brain barrier, targets M1 microglia, inhibits pyroptosis and inflammation, and scavenges ROS.
Huimin Shi, Qiuxia Gao, Wenying Wang, Bin Li, Yukun Chen, Zhijun Yao, Yujie Li, Junrui Li, Na Li, Gong Gu, Zhimin Hou, Mengyuan Yang, Ruilin Zhang, Hongju Yang, Yuhui Liao, Hongyi Lei   +15 more
wiley   +1 more source

Development of Textile Laminates for Improved Cut Resistance [PDF]

Journal of Engineered Fibers and Fabrics, 2010
Mechanical properties of fibres viz. tensile modulus, tenacity, elongation are the key performance indicators of cut resistance besides yarn and fabric structure. p-aramid and UHDPE (Ultra High Density Polyethylene) based high performance fibres are most
G. Thilagavathi, K. Rajendrakumar, T. Kannaian   +2 more
doaj  

Process Technology and Performance Evaluation of Nylon 6/PU Stab Resistance Fabric Matrix

, 2010
Stab resistance compound fabric is frequently used in daily life, industry, military and aerospace. In this study, Nylon 6 and Polyester short fibers were mixed in ratio of 70:30.
Jin Mao Chen, Cho Hsun Lee, Hung Jui Liang, Ching Wen Lou, Jia Horng Lin   +4 more
core   +1 more source

Introgressed Variation in TaMYB7‐A1 Drives Graded Dormancy and Climate‐Adaptive Pre‐Harvest Sprouting Resistance in Wheat

Advanced Science, EarlyView.
TaMYB7‐A1 directly activates TaABI5 to enhance ABA signaling and regulate ABA‐GA homeostasis, enforcing seed dormancy. Its superior allele, derived from wild einkorn introgression, harbors a MITE insertion that elevates expression and two amino acid substitutions that enhance transcriptional activity, collectively generating graded PHS resistance for ...
Hao Wang, Dongzhi Wang, Yafei Guo, Qi Zheng, Min Zhang, James Simmonds, Jian Hou, Xuemei Liu, Xuelei Lin, Xiaomin Bie, Xiansheng Zhang, Xiaohui Li, Yuan Chen, Xueyong Zhang, Cristobal Uauy, Fei Lu, Chengcai Chu, Zhixi Tian, Jun Xiao   +18 more
wiley   +1 more source

Effect of substrate fabric characteristics on the peel strength of 3D-printed composite fabrics

Fashion and Textiles
This study aimed to analyze those factors affecting the adhesion between substrate fabrics and 3D printing filaments by evaluating the influence of fabric surface characteristics, fiber composition, yarn type, and the fabric’s structure.
Yoojung Han, Changsang Yun
doaj   +1 more source

Optimization of B Cell Responses in Human Immune System Mice Through Organoid Based Screening

Advanced Science, EarlyView.
Human immune system (HIS) mice show limited B cell responses to immunization. Using HIS mouse spleen organoids, this study identifies cytokine combinations and innate immune signals that drive human B cell expansion, differentiation, and class‐switch. Applying these signals in vivo through temporal separation enables antigen‐specific IgG responses and ...
Haiqiao Sun, He Li, Xu Zhu, Zijian Zhang, Deshan Ren, Shuai Ding, Yan Li   +6 more
wiley   +1 more source

Synthesis of biscoumarin bifunctional reactive fluorescent whitening agents and their application on nylon-6 fabric [PDF]

, 2021
361-368Two new bifunctional reactive fluorescent whiting agents based on joining two coumarin moieties together through triazinyle-stilbene fluorescent moiety have been successfully synthesized, applied on nylon-6 fabrics and then characterized by NMR ...
El-Sedik, Mervat S, Megiede, Saadia A Abd El, Farouk, Reham, Mousa, Adalla A, Aysha, Tarek S   +4 more
core  

Multimodal Imaging Reveals Rapid Catecholamine Uptake and Release by Neutrophils

Advanced Science, EarlyView.
We show that immune cells (neutrophils) synthesize, uptake, and store catecholamine neurotransmitters such as dopamine or adrenaline. They also release them in response to specific stimuli (serotonin), which we directly visualize using fluorescent nanosensors. We further demonstrate that catecholamines affect neutrophil functions (NETosis) and platelet
Jennifer Mohr, Anne Schmitz, Meshkat Dinarvand, Franziska Wulfert, Sangeetha Shankar, Bjoern F. Hill, Michael Wojak, Juliana Gretz, Marie Britz, Elsa Neubert, Magdalena Shumanska, Sofia Kaushik, Linda Kartaschew, Ivan Bogeski, James Daniel, Sebastian Jung, Johannes Eble, Guido Wabnitz, Luise Erpenbeck, Sebastian Kruss   +19 more
wiley   +1 more source

ACLY‐Driven Metabolic Reprogramming Promotes Histone Acetylation and Inflammation‐Associated Fibrosis in Chronic Kidney Disease

Advanced Science, EarlyView.
This study reveals a citrate–ACLY–H3K27ac metabolic–epigenetic axis driving inflammatory gene activation and kidney fibrosis, highlighting ACLY inhibition as a potential therapeutic strategy for chronic kidney disease (CKD). ABSTRACT The mechanisms by which metabolic stress drives epigenetic dysregulation and fibrosis in chronic kidney disease (CKD ...
Chunxiu Du, Dhanunjay Mukhi, Lingzhi Li, Chenyu Li, Siyu Pan, Bernhard Dumoulin, Eunji Ha, Lakshmi P Kolligundla, Yanjuan Hou, Jonathan Levinsohn, Chaelin Kang, Konstantin Adrian Klötzer, Junnan Wu, Samer Mohandes, Kathryn E Wellen, Katalin Susztak   +15 more
wiley   +1 more source

SEM image of Velcro (TM)

, 2010
Velcro is a system of hard polymer hooks and soft nylon loops, both woven into backing fabric. Inspired by the natural seed propagation mechanism used by some plants in the form of 'burrs', Velcro was invented in Switzerland in 1948 by George de Mestral.
DoITPoMS, University of Cambridge, J A Curran, Department of Materials Science and Metallurgy, University of Cambridge   +1 more
core