Results 121 to 130 of about 730,755 (266)

Alteration of lipopolysaccharide O antigen leads to avirulence of gut-colonizing Serratia marcescens. [PDF]

Front Microbiol, 2023
Lee J, Kim JU, Lee BL, Kim JK.
europepmc   +1 more source

Risk Prediction Models for Recurrence After Curative Treatment of Early‐Stage or Locally Advanced Lung Cancer: A Systematic Review

Aging and Cancer, EarlyView.
This systematic review synthesizes prognostic models for survival and recurrence in resected non‐small cell lung cancer. While many models demonstrate moderate to good discrimination, few are externally validated and reporting quality is variable, limiting clinical applicability and highlighting the need for robust, transparent model development ...
Evangeline Samuel, S. Tissera, E. Paul, J. Zalcberg, R. G. Stirling   +4 more
wiley   +1 more source

Loss of O-antigen due to <i>wbbL</i> mutations is common and associated with increased mortality in <i>Escherichia coli</i> bloodstream infections. [PDF]

Sci Adv
Tyson KJ, Velez AZ, Hanson BM, Jiang J, Lu KY, Ruffin F, Sutton G, Brinkac LM, Clarke TH, Tao Y, Fouts DE, Adams MD, Arias CA, Khandelwal S, Fowler VG, Thaden JT, Conlon BP, Parsons JB.   +17 more
europepmc   +1 more source

Bacterial Virus Forcing of Bacterial O-Antigen Shields: Lessons from Coliphages. [PDF]

Int J Mol Sci, 2023
Letarov AV.
europepmc   +1 more source

Five‐Year Outcomes of Laparoscopic Sphincter‐Preserving Surgery for Rectal Cancer: A Prospective Study in Elderly Vietnamese Patients

Aging and Cancer, EarlyView.
This prospective study demonstrates that laparoscopic sphincter‐preserving surgery is feasible for elderly patients. While overall survival reaches 70% at 5 years, advanced T‐stage and the omission of neoadjuvant therapy significantly drive recurrence, highlighting the need for personalized geriatric protocols despite logistical challenges.
Huu Duc Ho, Quang Le, Ngoc Thach Tran, Van Viet Ung, Loc Vu   +4 more
wiley   +1 more source

Molecular epidemiology and structural diversity of O101/O162 O-antigen variants among Escherichia coli bacteremia isolates. [PDF]

Sci Rep
Weerdenburg E, de Been M, Zomer A, Ritmahan W, Lübbers J, Moran AB, Nicolardi S, Wuhrer M, Ravenscroft N, Anish C, Geurtsen J, Beurret M.   +11 more
europepmc   +1 more source

Chronobiology of Cancer: How Aging Fuels Oncogenesis at the Molecular Level

Aging and Cancer, EarlyView.
This graphical abstract illustrates the key biological pathways linking aging with cancer development and progression. In the upper left, cumulative exposure to ultraviolet radiation, toxins, and reactive oxygen species (ROS) causes DNA damage and genomic instability, whereas age‐related decline in repair mechanisms, such as ATM/ATR, BER, and NER ...
Anu Singh, Aroonima Misra, Sufian Zaheer
wiley   +1 more source

CRISPR-based mutagenesis of lipopolysaccharide biosynthesis genes in Leptospira interrogans reveals gene essentiality and confirms the role of an O-antigen polymerase. [PDF]

Sci Rep
Fernandes LGV, Nally JE.
europepmc   +1 more source

Developmental and Epileptic Encephalopathy due to Biallelic Pathogenic Variants in PIGM

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective PIGM encodes a critical enzyme in the glycosylphosphatidylinositol (GPI)‐anchor biosynthesis pathway. While promoter‐region mutations in PIGM have been associated with a relatively mild phenotype characterized by portal vein thrombosis and absence seizures, recent evidence suggests that coding‐region mutations result in a more severe
Júlia Sala‐Coromina, Anna Marcé‐Grau, Barbara Masotto, Marta Codina, Lamia BenJemaa, Yasmina Elaribi, Mónica Martinez‐Gallo, Roger Colobran, Angel Sanchez‐Montañez, Irene Valenzuela, Yoshiko Murakami, Alfons Macaya   +11 more
wiley   +1 more source

Differential virulence and immune recognition of <i>Klebsiella pneumoniae</i> O-antigen subtypes O2α and O2β. [PDF]

Infect Immun
Wantuch PL, Robinson LS, Knoot CJ, Harding CM, Rosen DA.   +4 more
europepmc   +1 more source