Results 111 to 120 of about 11,359,663 (315)

Adaptation of the Ultrasensitive HIV-1 p24 Antigen Assay to Dried Blood Spot Testing. [PDF]

, 2007
Implementation of molecular tests for the assessment of pediatric HIV-1 infection in resource-limited countries is difficult because of technical complexity and costs.
Speck, R F, Böni, J, Jullu, B, Schüpbach, J, Knuchel, M C, Mshinda, H, Schüpbach, Jörg, Nadal, D, Stoeckle, Marcel P, Tanner, M, Böni, Jürg, Shah, Cyril, Jullu, Boniphace, Speck, Roberto F, Shah, C, Tomasik, Z, Stoeckle, M P, Nadal, David, Tomasik, Zuzana, Mshinda, Hassan, Knuchel, Marlyse C, Tanner, Marcel   +21 more
core   +1 more source

Adaptor protein CIN85 potentiates the motility of osteosarcoma cells via the Akt/mTOR and MMP2‐COL3A1 axis

Molecular Oncology, EarlyView.
CIN85 is highly expressed in osteosarcoma, particularly in metastatic lesions. Its overexpression increases cell migration and Matrigel invasion, while silencing CIN85 suppresses these behaviors. Transcriptome analysis shows that CIN85 regulates MMP2, COL3A1, and Akt/mTOR signaling. Targeting these pathways reverses CIN85‐induced motility, highlighting
Iryna Horak, Iva Staniczková Zambo, Matěj Přikryl, Peter Múdry, Danica Zapletalová, Jarmila Navrátilová, Jiří Navrátil, Jan Šmarda, Liudmyla Drobot, Petr Beneš, Lucia Knopfová   +10 more
wiley   +1 more source

Localisation of the Ki-67 antigen within the nucleolus: Evidence for a fibrillarin-deficient region of the dense fibrillar component

, 1996
The Ki-67 antigen is detected in proliferating cells in all phases of the cell division cycle. Throughout most of interphase, the Ki-67 antigen is localised within the nucleolus.
Kill, IR
core  

Role of capsule and O antigen in the virulence of uropathogenic Escherichia coli.

, 2014
Urinary tract infection (UTI) is one of the most common bacterial infections in humans, with uropathogenic Escherichia coli (UPEC) the leading causative organism.
Minh-Duy Phan, Sarkar, Sohinee, Totsika, Makrina, Ulett, Glen C., Makrina Totsika, Glen C. Ulett, Ulett, Glen C, Schembri, Mark A, Minh-Duy, Phan, A. Schembri, Mark, Sohinee Sarkar, Mark A. Schembri, Ulett, Glen, Phan, Minh-Duy, Schembri, Mark A., Glen C Ulett, Mark A Schembri   +16 more
core   +1 more source

Convergent synthesis of the tetrasaccharide repeating unit of the cell wall lipopolysaccharide of Escherichia coli O40

Beilstein Journal of Organic Chemistry, 2012
A tetrasaccharide repeating unit corresponding to the cell-wall lipopolysaccharide of E. coli O40 was synthesized by using a convergent block glycosylation strategy.
Abhijit Sau, Anup Kumar Misra
doaj   +1 more source

Proteasome inhibitor, ixazomib prevents topoisomerase‐I degradation and reverses irinotecan resistance in colorectal cancer

Molecular Oncology, EarlyView.
Ixazomib inhibits proteasome‐mediated degradation of topoisomerase I induced by irinotecan, thereby restoring drug sensitivity and promoting tumor cell death in colorectal cancer. Irinotecan, a topoisomerase I (topoI) inhibitor, is widely used for colorectal cancer, but resistance remains a major clinical challenge.
Yuho Ebata, Koji Ando, Hirofumi Hasuda, Koshi Mimori, Elizabeth C. Unan, Siddhartha Pulukuri, Aahana Tiku, Allison Berger, Eiji Oki, Ajit Bharti, Tomoharu Yoshizumi   +10 more
wiley   +1 more source

The characterisation of the peanut agglutinin an evolved plant lectin, with improved specificity to the Thompson Freidenriech antigen

, 2013
Includes abstract.Includes bibliographical references.Peanut agglutinin (PNA), a carbohydrate binding protein, is able to recognise and bind a number of distinct carbohydrate structures that have been implicated in a number of disease pathologies in ...
Lagardien, Zaida
core  

Chromosomal Localization of the Carcinoembryonic Antigen Gene Family and Differential Expression in Various Tumors [PDF]

, 1988
Carcinoembryonic antigen (CEA) is a glycoprotein which is important as a tumor marker for a number of human cancers. It is a member of a gene family comprising about 10 closely related genes.
Weber, Bernhard, Weber, Bernhard H. F., Zimmermann, Wolfgang, Ortlieb, B., Shively, John E., Shively, J. E., Schempp, Werner, Fiebig, Heinz-Herbert, Thompson, John A., Ortlieb, Barbara, von Kleist, S., Rudert, F., Fiebig, H.-H., Zimmermann, W., Thompson, J. A., Kleist, Sabine von, Schempp, W., Rudert, Fritz   +17 more
core  

Intra- and Interspecies Analyses of the Carcinoembryonic Antigen (CEA) Gene Family Reveal Independent Evolution in Primates and Rodents [PDF]

, 1989
Various rodent and primate DNAs exhibit a stronger intra- than interspecies cross-hybridization with probes derived from the N-terminal domain exons of human and rat carcinoembryonic antigen (CEA)-like genes.
Zimmermann, Wolfgang, Thompson, John A., Rudert, Fritz   +2 more
core   +1 more source

GMMA-based vaccine candidates against invasive nontyphoidal salmonellosis elicit bactericidal antibodies against a panel of epidemiologically relevant Salmonellae

Frontiers in Immunology
Systemic disease caused by nontyphoidal Salmonella (NTS) represents a major cause of death and morbidity, especially in young children in sub-Saharan Africa.
Daniele De Simone, Marika Pinto, Maria Grazia Aruta, Marta Benincasa, Martina Carducci, Roberta Di Benedetto, Francesco Citiulo, Miren Iturriza, Elli Mylona, Stephen Baker, Mariagrazia Pizza, Carlo Giannelli, Francesca Mancini, Rocío Canals, Omar Rossi   +14 more
doaj   +1 more source