Results 151 to 160 of about 14,762,033 (298)

Glycosylation of Wall Teichoic Acids in Gram-Positive Bacteria

open access: yes, 2011
The biosynthetic enzymes involved in wall teichoic acid biogenesis in Grampositive bacteria have been the subject of renewed investigation in recent years with the benefit of modem tools of biochemistry and genetics. Nevertheless, there have been only
Allison, Sarah
core  

Unraveling A4GALT Mechanism and Its Modulation With Adamantyl‐Galactosylceramide Analogues: Advancing Fabry Disease Therapeutic Strategies

open access: yesAngewandte Chemie, EarlyView.
A 310‐helix‐mediated conformational switch promotes a front‐face SNi‐like catalysis by human A4GALT. Mechanism‐guided design identifies AdaGalCer as a selective modulator of globotriaosylceramide (Gb3) biosynthesis, opening a clear route toward new Fabry disease therapeutics.
Nicky de Koster   +13 more
wiley   +2 more sources

Proteomic Analysis of N- and O-linked Glycosylation based on Hydrophilic Interaction Chromatography

open access: yes, 2013
Proteomic Analysis of N- and O-linked Glycosylation based on Hydrophilic Interaction ...
叶明亮   +4 more
core  

Various Hepatic Fibrosis Markers Should Be Evaluated for Causing Complications After Hepatectomy

open access: yes
Annals of Gastroenterological Surgery, EarlyView.
Toru Ikegami   +3 more
wiley   +1 more source

Protein O-Glycosylation Shapes Lymphatic Endothelia and Lymph Node Macrophage Populations. [PDF]

open access: yesFASEB J
Frey J   +11 more
europepmc   +1 more source

Synthesis and Activity‐Based Protein Profiling Identifies Aldo‐Keto Reductase 1C3 as Target Protein of Myxoglucamides

open access: yesAngewandte Chemie International Edition, EarlyView.
Myxoglucamide A—a novel glycolipopeptide isolated from myxobacteria—was synthesized, and activity‐based protein profiling identified aldo‐keto reductase 1C3 (AKR1C3) as its main target in human cells. Structure‐activity relationship studies, together with biophysical characterization and X‐ray crystallography, elucidated the structural basis of AKR1C3 ...
Thomas Siemon   +9 more
wiley   +1 more source

Restoring O-glycosylation and expression of MUC2 limits progression of colorectal cancer. [PDF]

open access: yesCell Death Dis
Yang Y   +9 more
europepmc   +1 more source

A Portal‐Preorganized Cucurbit[7]uril‐Ruthenium Conjugate Enables Motif‐Selective Protein Sensing

open access: yesAngewandte Chemie International Edition, EarlyView.
Reprogramming cucurbit[7]uril (CB7) recognition through portal engineering transforms an optically silent host into a motif‐selective photoluminescent receptor. The portal‐preorganized CB7‐Rubpy conjugate directly reports changes in aromatic motif accessibility, enabling optical sensing of protein misfolding and refolding.
Patrick Gruhs   +10 more
wiley   +1 more source

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