An escherichia coli vaccine co-expressing listeriolysin-O and tumour antigen in cancer immunotherapy and the mechanisms of immune regulation [PDF]
PhDSome recombinant bacterial strains have been shown to be very efficient in experimental therapies against cancer in rodent models. Amongst them is an E. coli that expresses the Listeriolysin-O protein (LLO) and a model tumour antigen ovalbumin (OVA)
Dai, Ming-Shen
core +4 more sources
Elucidation of the O-antigen structure of Escherichia coli O93 and biosynthetic aspects thereof [PDF]
The structure of the O-antigen from the international reference strain Escherichia coli O93:−:H16 has been determined. A nonrandom modal chain-length distribution was observed for the lipopolysaccharide, a pattern which is typical when long O-specific ...
Claudio , Muheim +6 more
core +1 more source
NanoAPC deliver antigen, IL-2 and co-stimulatory molecules to antigen specific T cells and activate viral specific T cells in chronic infections [PDF]
This thesis was submitted for the degree of Doctor of Philosophy and awarded by Brunel University.The study of the immune system has provided insight in the mechanism of protection induced by vaccination; primarily that most clinically protective ...
Liu, Mengya
core +6 more sources
Antigenic Relationships Between Escherichia coli O Antigens O 149 to O 163 and Shigella O Antigens [PDF]
O antigens O 149 to O 163 are recent additions to the Escherichia coli antigenic scheme. Their antigenic relationships with Shigella serovars were examined. O antigen identity was demonstrated between E. coli O 149 and Shigella boydii 1 and between E. coli O 152 and provisional Shigella serovar 3341-55.
B. ROWE, R. J. GROSS, M. GUINEY
openaire +1 more source
Citrobacter O-antigens: structure of the O-antigenic polysaccharide from Citrobacter sp. 396 [PDF]
The structure of the O-specific polysaccharide moiety of the lipopolysaccharide from Citrobacter 396 was elucidated by composition, methylation, and periodate oxidation studies. The repeating unit consists of four 2-linked mannoses and one 3-linked N-acetylglucosamine.
B, Jann, P, Prehm, K, Jann
openaire +2 more sources
Recent insights into Wzy polymerases and lipopolysaccharide O-antigen biosynthesis. [PDF]
Bacteria synthesize a plethora of complex surface-associated polysaccharides which enable them to persist and thrive in distinct niches. These glycans serve an array of purposes pertaining to virulence, colonization, antimicrobial resistance, stealth ...
Ascari A, Morona R.
europepmc +2 more sources
Reinvestigation of the structure of Brucella O-antigens [PDF]
O-Specific polysaccharides of Brucella contain two antigenic determinants, called A and M. Most of the strains express epitope A with a small amount of epitope M, whereas Brucella melitensis strain 16 M expresses longer polymer consisting mostly of M-type epitopes.
Kubler-Kielb, J., Vinogradov, E.
openaire +3 more sources
Lipophilic O-antigens in Rhodospirillum tenue [PDF]
Lipopolysaccharides of eight wild-type strains of the phototrophic bacterium Rhodospirillum tenue have been analyzed. All of the lipopolysaccharides are highly lipophilic. The compositions of preparations obtained by the phenol-water or by the phenol-chloroform-petroleum ether procedure are very similar. The polysaccharide moiety, obtained by mild acid
J, Weckesser +3 more
openaire +2 more sources
Lipopolysaccharide (LPS) is a ubiquitous microbial-associated molecular pattern. Plants can sense the three components of LPS, including core polysaccharide, lipid A, and O-antigen. LPS biosynthesis is an essential factor for the successful establishment
Zhide Tang +7 more
doaj +1 more source
Isolation, characterization and immunolocalization of a globin-like antigen from Ostertagia ostertagi adults [PDF]
Western blot analysis using an anti-globin rabbit serum Rb94 revealed a major band of 17 kDa in extracts of Ostertagia ostertagi adults and 4th-stage larvae.
De Marez, Tine +23 more
core +1 more source

