Results 191 to 200 of about 16,308,338 (297)

Prostate Cancer Patient‐Derived Organoids (PDOs) as Functional Avatars for Antisense Oligonucleotide (ASO)‐Based Personalized Therapy

Advanced Healthcare Materials, EarlyView.
Prostate patient‐derived organoids (PDOs) were established from TURP and biopsy specimens with >90% success and retain key features of their tissues of origin, making them functional avatars for antisense oligonucleotide (ASO) therapy . Transfecting single cells outside the Matrigel matrix and then reconstituting organoids overcomes the 3D delivery ...
Thi Thom Tran, Thi Tu Uyen Phan, Michael Baboudjian, Quang Hieu Duong, Ines Sousa, Thi Thuy Le, Virginie Baylot, Sophie Giusiano, Laurent Daniel, Pauline Brige, Benjamin Guillet, Cyrille Bastide, Carmen Garrido, David Taïeb, Thi Khanh Le, Palma Rocchi   +15 more
wiley   +1 more source

Cross-comparison study of three ELISA methodologies to measure <i>Shigella Sonnei</i> O-antigen serum IgG. [PDF]

mSphere
Stickings P, Vipond C, Rigsby P, Micoli F, Rossi O, Mancini F, Conti V, Cohen D, Bialik A, Meron-Sudai S, Asato V, Clarkson KA, MacLennan CA, Kaminski RW.   +13 more
europepmc   +1 more source

Spatially Controlled Embedded Bioprinting of Prevascularized Spheroids‐Containing Biopatch Enables Functional Skin Regeneration

Advanced Healthcare Materials, EarlyView.
A spatially controlled embedded bioprinting strategy enables precise engineering of prevascularized multicellular spheroids within skin‐derived dECM bioinks. Optimized spheroid size, composition, and spacing promote vascular maturation, paracrine signaling, and tissue integration, resulting in enhanced angiogenesis, blood perfusion, and functional skin
Minjun Ahn, Gyu Tae Park, Dongjun Lee, Sik Yoon, Sae‐Ock Oh, Jae Ho Kim, Byoung Soo Kim   +6 more
wiley   +1 more source

<i>Shigella</i> Mutant with Truncated O-Antigen as an Enteric Multi-Pathogen Vaccine Platform. [PDF]

Vaccines (Basel)
Kim JO, Nothaft H, Moon Y, Jeong S, Vortherms AR, Song M, Szymanski CM, White J, Walker R.   +8 more
europepmc   +1 more source

Advancing Human Skin Equivalents: The Crucial Role of Neurovascular Integration

Advanced Healthcare Materials, EarlyView.
This review discusses the importance of integrating vascular and peripheral nerve systems into human skin equivalents (HSEs) to better recapitulate native skin physiology. Recent advances in vascularized, innervated, and neurovascularized HSEs are highlighted, together with emerging bioengineering strategies, current challenges, and future ...
Hao Wu, Lorenzo Moroni, Nicolas Lebonvallet, Vincent Flacher, Paul Wieringa   +4 more
wiley   +1 more source

O-antigen polysaccharides in <i>Klebsiella pneumoniae</i>: structures and molecular basis for antigenic diversity. [PDF]

Microbiol Mol Biol Rev
Whitfield C, Kelly SD, Stanton TD, Wyres KL, Clarke BR, Forrester TJB, Kowalczyk A.   +6 more
europepmc   +1 more source

Self‐Healing Hydrogel‐Enabled Modular Assembly of Bilayered Skin Construct for Hair Follicle Regeneration

Advanced Healthcare Materials, EarlyView.
Self‐healing assembly of two cell‐laden hydrogel layers creates a biomimetic skin construct that restores both dermal and epidermal functions, resulting in accelerated wound healing and enhanced hair follicle regeneration in a full‐thickness skin wound model. ABSTRACT Alopecia remains a pervasive clinical challenge, largely owing to the limited ability
JaeWook Park, Su Yong Kim, MinSu Jeong, Beom Joon Kim, Shin Hyuk Kang, Won‐Gun Koh   +5 more
wiley   +1 more source

A multifunctional anti-O-Antigen human monoclonal antibody protects against <i>Shigella sonnei</i> infection in vivo. [PDF]

Proc Natl Acad Sci U S A
Ridelfi M, Vezzani G, Roscioli E, Batani G, Boero E, Nannini F, Marini E, Bhaumik U, Desalegn G, Serpino O, Molinaro A, Paciello I, Mugnaini C, De Santi C, Maccari G, De Rosa A, Valensin S, Duatti A, Di Benedetto R, Raso MM, Alfini R, Sammicheli C, Tavarini S, Quigley C, Podda A, Kabanova A, Andreano E, Cardamone D, Gasperini G, Necchi F, Pizza M, Martin LB, Frenck RW, Grassart A, Silipo A, Pasetti MF, Berlanda Scorza F, Giannelli C, Rossi O, Micoli F, Sala C, Rappuoli R.   +41 more
europepmc   +1 more source

Inflammation Unchecked: Concurrent Kawasaki Disease and Stevens‐Johnson Syndrome in an 18‐Month‐Old Child

Arthritis Care &Research, EarlyView.
Catherine Deffendall, Jodi Backalar, Elizabeth Acevedo Zapata, Adriana Della Porta, Lorin Bibb, Tyler Reese, Charlotte M. Brown   +6 more
wiley   +1 more source

Multiplexed Detection of Respiratory Viruses Using Surface Plasmon Resonance Spectroscopy With Ultrathin Carbon Nanomembranes

Advanced Healthcare Materials, EarlyView.
An ultrathin azide‐functionalized carbon nanomembrane (N3‐CNM) provides a versatile biointerface for antibody immobilization on gold SPR sensors. Integrated with a multichannel SPR platform, the functionalized surface enables label‐free, simultaneous detection of SARS‐CoV‐2, Influenza A, and RSV antigens, demonstrating the potential of CNM‐based ...
Ghazaleh Eshaghi, Hamid Reza Rasouli, David Kaiser, Tobias Fischer, Katrin Frankenfeld, Abhishek Sharma, Andrey Turchanin   +6 more
wiley   +1 more source