Results 101 to 110 of about 2,244 (165)

Metabolic disruption in early life: the role of endocrine disruptors in pediatric obesity

Pediatria Polska
Child and adolescent obesity is a significant and increasingly prevalent public health challenge. Among the contributing factors are endocrine-disrupting chemicals (EDC), which interfere with pathways regulating adipogenesis and metabolic homeostasis ...
Jakub Kleinrok, Weronika Pająk, Joanna Pec, Jan Wojtas, Jacek Baj   +4 more
doaj   +1 more source

Perfluorinated Alkyl Acids in Plasma of American Alligators (Alligator Mississippiensis) from Florida and South Carolina [PDF]

This study aimed to quantitate fourteen perfluoroalkyl acids (PFAAs) in 125 adult American alligators at twelve sites across the southeastern US. Of those fourteen PFAAs, nine were detected in 65% - 100% of the samples: PFOA, PFNA, PFDA, PFUnA, PFDoA ...
Bangma, Jacqueline T., Bowden, John A., Brunell, Arnold M., Christie, Ian, Finnell, Brendan, Guillette, Louis J., Jr., Guillette, Matthew P., Jones, Martin, Lowers, Russell H., Rainwater, Thomas R., Reiner, Jessica L., Wilkinson, Philip M.   +11 more
core   +1 more source

Delineating lipidomic landscapes in human and mouse ovaries: Spatial signatures and chemically-induced alterations via MALDI mass spectrometry imaging

Environment International
This study addresses the critical gap in understanding the ovarian lipidome’s abundance, distribution, and vulnerability to environmental disruptors, a largely unexplored field.
Natalia Pascuali, Fernando Tobias, Klara Valyi-Nagy, Sana Salih, Almudena Veiga-Lopez   +4 more
doaj   +1 more source

Per- and Polyfluoroalkyl Substances (PFAS) as Emerging Obesogens: Mechanisms, Epidemiological Evidence, and Regulatory Challenges

Physiologia
The pervasive presence of per- and polyfluoroalkyl substances (PFAS) in the environment and their persistent nature raise significant concerns regarding their impact on human health.
Niya Lewis, Abubakar Abdulkadir, Shila Kandel, Raphyel Rosby, Ekhtear Hossain   +4 more
doaj   +1 more source

Impact of Metabolic disrupting chemicals on redox homeostasis, energy sensors, receptor modulation, and hormone metabolism: A comparative account in Teleost and mammalian model organisms

Aquaculture and Fisheries
Endocrine-disrupting chemicals (EDCs) may mimic the endogenous neuroendocrine and endocrine messengers and interfere with developmental, reproductive, immune, metabolic and other physiological functions.
Urmi Mukherjee, Sudipta Maitra
doaj   +1 more source

Identification of pharmaceuticals and environmental contaminants as obesogens inducing a locomotion-independent thrifty phenotype

Communications Biology
Obesity is a global pandemic that affects people of all ages. While behavioral, nutritional, and socioeconomic factors all contribute to weight gain, other factors in our immediate environment play an insidious role in the prevalence of obesity. Exposure
Sara Al Kassir, Théo Mercé, Laure M. Bourcier, Sandra Pedemay, Magalie Soares, Anja Knoll-Gellida, Patrick J. Babin   +6 more
doaj   +1 more source

Molecular mechanisms of endocrine disruptors: Interference with the endocrine system activity [PDF]

, 2018
Endocrine disrupting chemicals (EDCs) are an heterogeneous group of compounds able to interfere with hormonal functions by mimicking the endogenous hormones.
Falco, De, Laforgia, Vincenza
core  

From a toxin to an obesogen: a review of potential obesogenic roles of acrylamide with a mechanistic approach. [PDF]

Nutr Rev, 2023
Buyukdere Y, Akyol A.
europepmc   +1 more source

Obesogens in Prostate Cancer: An Endocrine and Metabolic Threat. [PDF]

Curr Obes Rep
Feijó M, Fonseca LRS, Kiss-Toth E, Socorro S, Correia S.   +4 more
europepmc   +1 more source

Machine Learning Models for High-Throughput Screening of Obesogens Based on Pathway Network. [PDF]

Environ Health (Wash)
Wang X, Huang Y, Li F, Wang J, Ji C, Wu H, Pan Y, Dai J.   +7 more
europepmc   +1 more source