Results 171 to 180 of about 7,368,420 (284)

PrOMet: Accurate and Robust Metal‐Binding Site and Type Prediction

open access: yesAdvanced Science, EarlyView.
PrOMet is a two‐stage deep learning framework for jointly predicting metal‐binding sites and ion identities from protein structures. Surface candidate sites are first pruned, followed by refinement of the most probable sites and metal types. This hierarchical strategy enables robust and accurate metal prediction for cryo‐EM and AlphaFold‐derived ...
Gangeun Park, Chaok Seok, Hahnbeom Park
wiley   +1 more source

Protean and bounderyless career attitudes: relationships with subjective and objective career success

open access: yes
"The protean and boundaryless career attitudes have gained special attention during the past years. A protean career attitude implies that a person strives towards a developmental progression and self-fulfillment; a boundaryless career attitude is ...
Spurk, Daniel, Volmer, Judith
core  

Field‐Driven Active Colloids as Distributed Micromachines: Bridging Physics, Control, and Function Across Length Scales

open access: yesAdvanced Science, EarlyView.
Field‐driven active colloids are framed as distributed micromachines in which externally supplied power, sensing, and control regulate task‐relevant states. By closing the loop between particle behavior, imaging, computation, and electric or magnetic actuation, these systems can progress from programmable motion toward adaptive functional outcomes ...
Ruchi Patel, Bhuvnesh Bharti
wiley   +1 more source

A Living Multi‐Omics PDX Biobank of High‐Risk Sarcomas Reveals ecDNA‐Driven Oncogene Amplification in Osteosarcoma and Enables Preclinical Precision Oncology

open access: yesAdvanced Science, EarlyView.
A living multi‐omics sarcoma PDX biobank is enriched for high‐risk disease and preserves key patient tumor features at histopathological and molecular levels. Integrated profiling reveals ecDNA‐driven oncogene amplification in osteosarcoma and preferential retention of ecDNA during PDX evolution.
Weisong Zhao   +34 more
wiley   +1 more source

Precision Nanomedicine for Traumatic Neural Injury: Functional Paradigms and Translational Frameworks

open access: yesAdvanced Science, EarlyView.
This review presents a pathology‐driven framework unifying nanomedicine across TBI, SCI, and PNI. Epidemiological evidence and comparative single‐cell transcriptomic reanalysis define shared pathological modules, injury‐specific effectors, and therapeutic bottlenecks. Six functional paradigms connect nanomaterial structure and biological fate to injury‐
Mouyuan Sun   +12 more
wiley   +1 more source

Patriarchal dominance, employment anxiety and subjective career success among career widows in Nigeria. [PDF]

open access: yesBMC Psychol
Obi-Anike HO   +6 more
europepmc   +1 more source

Data‐Driven and Physics‐Informed Modeling Perspectives for Soft Manipulators: From SINDy to Hybrid Intelligence

open access: yesAdvanced Science, EarlyView.
This Perspective charts the modeling landscape for soft manipulators, spanning sparse system identification, neural dynamics, physics‐informed models and hybrid intelligence. We examine how physics, data, sensing, adaptation and control can assume complementary roles within this landscape, and provide a framework for selecting modeling approaches ...
Wenbo Hui   +4 more
wiley   +1 more source

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