Results 31 to 40 of about 323,203 (269)

Central Nervous System Neuroblastoma, FOXR2‐Activated: A Pooled Analysis of Published Clinical Outcomes

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Central nervous system (CNS) neuroblastoma, FOXR2‐activated, is a recently recognized entity in the WHO CNS5 classification, defined by activation of the FOXR2 transcription factor and unique histopathological features. This review synthesizes available literature and pooled clinical data, providing insight into demographics ...
Sudarshawn Damodharan, Mohamed S. Abdelbaki   +1 more
wiley   +1 more source

Acceptance of Trial of Labor After Cesarean  Among Obstetricians in the Eastern Province of Saudi Arabia: A Cross-Sectional Study.

Annals of Abbasi Shaheed Hospital and Karachi Medical & Dental College
Objectives: To analyze the acceptance of the trial of vaginal delivery after cesarean birth, to identify associated factors, and to evaluate obstetricians’ satisfaction with the trial. Methods: This cross-sectional, questionnaire-based online survey was
Fehmida Tehsin, Fatimah Abdrabalrasool A. Alsafar, Fatima Ali S. Al Amer, Farah Fahad M. ALMuqrin , Kawther Muneer A. Alsaffar   +4 more
doaj   +1 more source

Feasibility and Safety of Somato‐Cognitive Coordination Therapy for Cerebellar Ataxia Following Pediatric Brain Tumor Treatment

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Cerebellar ataxia after pediatric brain tumor treatment can cause persistent gait, balance, and speech impairment, yet no established rehabilitation strategy exists. Somato‐cognitive coordination therapy (SCCT) is a virtual reality–guided intervention designed to promote sensorimotor integration through visually constrained reaching
Masanobu Takeuchi, Takashi Matsuzawa, Jun Yamanishi, Masahiro Yoshitomi, Junji Ikeda, Shin‐Ichi Tsujimoto, Yasuteru Yamaguchi, Norio Shiba, Dhroov Pathare, Ayumi Kato, Masahiko Hara   +10 more
wiley   +1 more source

Using a peanut ball during labour versus not using a peanut ball during labour for women using an epidural: study protocol for a randomised controlled pilot study

Pilot and Feasibility Studies, 2018
Background The peanut ball has only been recently used as a support for women labouring with epidurals. The peanut ball is shaped like a peanut and fits snugly between the woman’s legs so that both legs are maintained as opening the pelvic outlet to ...
Virginia Stulz, David Campbell, Biing Yin, Wafa Al Omari, Robin Burr, Heather Reilly, Kenny Lawson   +6 more
doaj   +1 more source

An App-Based Parenting Program to Promote Healthy Energy Balance–Related Parenting Practices to Prevent Childhood Obesity: Protocol Using the Intervention Mapping Framework

JMIR Formative Research, 2021
BackgroundThe family environment plays an important role in the development of children’s energy balance–related behaviors. As a result, parents’ energy balance–related parenting practices are important targets of preventive childhood obesity programs ...
Karssen, Levie T, Vink, Jacqueline M, de Weerth, Carolina, Hermans, Roel C J, de Kort, Carina P M, Kremers, Stef PJ, Ruiter, Emilie L M, Larsen, Junilla K   +7 more
doaj   +1 more source

Sustained Therapeutic Efficacy of Intravenous Plasminogen Concentrate in Pediatric Patients With Type 1 Plasminogen Deficiency: An Analysis of Dosing Parameters and Clinical Outcomes

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Type 1 plasminogen deficiency (PLGD‐1) is an ultra‐rare autosomal recessive disorder caused by variants in the PLG gene and affects approximately 1.6 individuals per million. The condition is characterized by decreased plasminogen levels and impaired function, resulting in fibrin‐rich lesions on mucous membranes throughout the body.
Charles Nakar, Karen Thibaudeau, Mary Mathias, Heather McDaniel, Madlen Reschke, Klaus Tenbrock, Joseph M. Parker, Amy Shapiro   +7 more
wiley   +1 more source

A Combined Digital and Biomarker Diagnostic Aid for Mood Disorders (the Delta Trial): Protocol for an Observational Study

JMIR Research Protocols, 2020
BackgroundMood disorders affect hundreds of millions of people worldwide, imposing a substantial medical and economic burden. Existing diagnostic methods for mood disorders often result in a delay until accurate diagnosis, exacerbating the challenges of ...
Olmert, Tony, Cooper, Jason D, Han, Sung Yeon Sarah, Barton-Owen, Giles, Farrag, Lynn, Bell, Emily, Friend, Lauren V, Ozcan, Sureyya, Rustogi, Nitin, Preece, Rhian L, Eljasz, Pawel, Tomasik, Jakub, Cowell, Daniel, Bahn, Sabine   +13 more
doaj   +1 more source

How to enhance recruitment of individuals at risk of rheumatoid arthritis into trials aimed at prevention: understanding the barriers and facilitators

RMD Open, 2021
Objectives Several trials to test the efficacy of a pharmacological intervention aimed at primary prevention of rheumatoid arthritis (RA) are ongoing or have recently been completed.
Dirkjan van Schaardenburg, Laurette van Boheemen, Bart Seppen   +2 more
doaj   +1 more source

Rational Use of Herbal Products in Pediatric Patients Treated With Anticancer Drugs in the European Union

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Introduction The use of herbal medical preparation (HMP) is rising among pediatric oncology patients, often to manage treatment‐related symptoms. Their effectiveness remains uncertain, and the risk of herb–drug interactions is underestimated.
Orianne Mahot, Mathieu Corvaisier, Laurence Spiesser‐Robelet, Mylène Duplan, Isabelle Pellier, Delphine Bourneau‐Martin, Séverine Derbré   +6 more
wiley   +1 more source

ALICE: a randomized placebo-controlled phase II study evaluating atezolizumab combined with immunogenic chemotherapy in patients with metastatic triple-negative breast cancer

Journal of Translational Medicine, 2020
Background Immunotherapy with checkpoint inhibitors (CI) represents an important novel development in cancer treatment. Metastatic triple-negative breast cancer (mTNBC) is incurable, with a median survival of only ~ 13 months.
J. A. Kyte, A. Røssevold, R. S. Falk, B. Naume   +3 more
doaj   +1 more source