Results 41 to 50 of about 371,247 (318)

Objectively Measured Physical Activity as a COPD Clinical Trial Outcome

Chest, 2021
Reduced physical activity is common in COPD and is associated with poor outcomes. Physical activity is therefore a worthy target for intervention in clinical trials; however, trials evaluating physical activity have used heterogeneous methods.What is the available evidence on the efficacy and/or effectiveness of various interventions to enhance ...
Burtin, Chris, Mohan, Divya, Troosters, Thierry, Watz, Henrik, Hopkinson, Nicholas S., Garcia-Aymerich, Judith, Moy, Marilyn L., Vogiatzis, Ioannis, Rossiter, Harry B., Singh, Sally, Merrill, Debora D., Hamilton, Alan, Rennard, Stephen, Fageras, Malin, Petruzzelli, Stefano, Tal-Singer, Ruth, Tomaszewski, Erin, Corriol-Rohou, Solange, Rochester, Carolyn L., Sciurba, Frank C., Casaburi, Richard, Man, William D-C., Van Lummel, Rob C., Cooper, Christopher B., Demeyer, Heleen, Spruit, Martijn A., Vaes, Anouk   +26 more
openaire   +6 more sources

Kidney function in the very elderly with hypertension: data from the hypertension in the very elderly (HYVET) trial.

, 2013
BACKGROUND: numerous reports have linked impaired kidney function to a higher risk of cardiovascular events and mortality. There are relatively few data relating to kidney function in the very elderly. METHODS: the Hypertension in the Very Elderly Trial (
Narkiewicz, Krzysztof, Beckett, Nigel, Fagard, Robert, Bulpitt, Christopher, Wang, Nan, Fletcher, Astrid, Peters, Ruth, Nitsch, Dorothea, Burch, Lisa, Li, Mengying, Poulter, Ruth   +10 more
core   +1 more source

Usual care in a multicentre randomised controlled trial of financial incentives for smoking cessation in pregnancy: qualitative findings from a mixed-methods process evaluation [PDF]

, 2022
OBJECTIVES: Financial incentives are recommended by the UK’s National Institute for Health and Care Excellence to aid smoking cessation in pregnancy.
Jennifer McKell, Sinclair, Lesley, Tappin, David, Pat Hoddinott, Harris, Fiona M., McKell, Jennifer, Bauld, Linda, Fiona M Harris, Harris, Fiona M, Bauld, Linda; id_orcid, Tappin, David Michael, Linda Bauld, Lesley Sinclair, Hoddinott, Pat, David Michael Tappin   +14 more
core   +1 more source

Hospitalization Through Families’ Eyes: Comparing Inpatient Care Quality for Children With Sickle Cell Disease and Cystic Fibrosis in Canada

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Sickle cell disease (SCD) is a chronic, inherited hemoglobinopathy that requires frequent hospitalization for disease‐related complications. Canadian data on inpatient care is limited. This study compared caregiver‐reported hospital experiences of children with SCD to those with cystic fibrosis (CF), a chronic, autosomal recessive ...
Hailey M. Zwicker, Kyle Kemp, Perri Tutelman, Sharon H. J. Hou, Paul Fairie, Maria Santana, Gregory M. T. Guilcher, Taryn Fay‐McClymont, Glenda Bendiak, Wendy Pelletier, Nicola Wright, Fiona Schulte   +11 more
wiley   +1 more source

Venous Thromboembolism in Pediatric Bone Sarcoma Patients: A 10‐Year, Single‐Institution Experience Encompassing the COVID‐19 Pandemic

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Osteosarcoma (OS) and Ewing sarcoma (EWS) are the most common primary bone cancers in children, but acute thrombosis is poorly characterized in this population. Our study evaluated the rates of venous thromboembolism (VTE) and associated risk factors in pediatric patients with bone sarcomas treated over a 10‐year period encompassing
Sarah Kappa, Shou Xu, Mark Zobeck, Sarah E. Sartain, Nino Rainusso, Lisa Wang, Nicole Montgomery, Paige Wheaton, Sarah Whittle   +8 more
wiley   +1 more source

A Controlled Trial of Objective Measures of Sunscreen and Moisturizing Lotion [PDF]

Cancer Epidemiology, Biomarkers & Prevention, 2009
Abstract Taking an alcohol swab of a person's forearm and analyzing it using a spectrophotometer has been shown to be a reliable method for detecting the presence of sunscreen. The aims of this study were to determine if moisturizing lotions or other non-sunscreen products influence the absorbance readings from skin swabs in a controlled
Tom, Elliott, Eric J, Nehl, Karen, Glanz
openaire   +2 more sources

Guided self-help cognitive behavioural therapy for depression in primary care: a randomised controlled trial [PDF]

, 2013
<br>Background: Access to Cognitive behavioural therapy (CBT) for depression is limited. One solution is CBT self-help books.</br> <br>Trial Objectives: To assess the impact of a guided self-help CBT book (GSH-CBT) on mood, compared ...
Louise Tansey (104027), McMahon, Alex, Walker Andrew (104016), McNeill, Y., Williams, Christopher, Walker, A., Yvonne McNeill, Tansey, Louise, Tansey, L., Alex McConnachie (104022), Christopher Williams (104003), Jill Morrison (104009), Wilson, P., Allan, Lesley, Wilson, Philip, Alex McMahon, Andrew Walker, Alex McMahon (104012), Alex McConnachie, McConnachie, A., Philip Wilson, Williams, C., Christopher Williams, Lesley Allan, Allan, L., Lesley Allan (104019), Yvonne McNeill (104024), McConnachie, Alex, McMahon, A., Louise Tansey, Walker, Andrew, McNeill, Yvonne, Philip Wilson (104007), Morrison, J., Jill Morrison, Morrison, Jill   +35 more
core   +1 more source

Deep Sequencing of FLT3‐ITD Enables Response Evaluation and Post‐Treatment Monitoring in Childhood AML: An Exploratory Study

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background An internal tandem duplication in the gene encoding Fms‐like tyrosine kinase 3 (FLT3‐ITD) is associated with high relapse risk and poor prognosis in acute myeloid leukemia (AML) and plays a crucial role in treatment decisions. Measurable residual disease (MRD) analysis of FLT3‐ITD during and after treatment has shown prognostic ...
Sofie Johansson Alm, Bea Tornberg, Erik Delsing Malmberg, Henrik Hasle, Kristian Løvvik Juul‐Dam, Lars Palmqvist, Borhan R. Saeed, Giti Shah Barkhordar, Anastasia Soboli, Anna Staffas, Jonas Abrahamsson, Linda Fogelstrand   +11 more
wiley   +1 more source

Thrombosis prevention trial: follow-up study of practical implications. [PDF]

, 2002
The impact of randomised controlled trials on subsequent practice has only occasionally been assessed. Doing so is particularly necessary when unusual and possibly controversial treatments are being used. The aim of this study was to assess the practical
Brennan, PJ, Meade, TW, Fasey, N, MRC General Practice Research Framework. Medical Research Counci   +3 more
core  

Heterogeneity in the Global Practice of Central Nervous System Staging in Pediatric Acute Lymphoblastic Leukemia

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Central nervous system (CNS) involvement in childhood acute lymphoblastic leukemia (ALL) is assessed by cell counting and cytomorphology from cerebrospinal fluid (CSF) and is used for treatment stratification worldwide. The ratio of “CNS2” patients in clinical trials ranges from 3% to 40%, with unclear prognostic significance ...
Laura Almási, Bernadett Borbála Huszti, Gábor Barna, Marko Kavcic, Janez Jazbec, Lennart Lenk, Vera Münch, Sophia Polychronopoulou, Ágnes Márk, Maria Thastrup, Lüder H. Meyer, Kjeld Schmiegelow, Cornelia Eckert, Christina Halsey, Dániel J. Erdélyi   +14 more
wiley   +1 more source