Results 61 to 70 of about 499,553 (301)
FEBS Letters, EarlyView.Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson +7 more
wiley +1 more source
Věcnost v povídkách Ladislava Dvořáka // Objectivity in short stories of Ladislav Dvořák [PDF]
Slovo a Smysl, 2017 The article examines the prosaic works of Ladislav Dvořák (1920–1983), specifically the collection of short stories entitled Šavle meče. It analyses the construction of Dvořák’s texts with regard to their significant aspect, the connection between ...
Zuzana Pokorná
doaj
Molecular Oncology, EarlyView.In this exploratory study, we investigated the relationship between the gut microbiota and outcome in patients with metastatic hormone receptor‐positive breast cancer, treated in a randomized clinical trial with chemotherapy alone or chemotherapy in combination with immune checkpoint blockade.
Andreas Ullern +7 more
wiley +1 more source
An object lesson in objection [PDF]
Journal of Family Planning and Reproductive Health Care, 2008 Theres always been conscientious objection in medicine. The inherent egotistical "this is how its done and what youll do if you want to get on" attitude that medicine breeds means its often hidden. Or its tough to carry out your objection. I object to having to see patients - wait I havent finished yet - when Ive got laryngitis for instance. Most of us
openaire +2 more sources
Molecular Oncology, EarlyView.Genetic testing in epithelial ovarian cancer includes both germline and tumor‐testing. This approach often duplicates resources. The current prospective study assessed the feasibility of tumor‐first multigene testing by comparing tumor tissue with germline testing of peripheral blood using an 18‐gene NGS panel in 106 patients.
Elisabeth Spenard +12 more
wiley +1 more source
Aspects of Objectivity in Quantum Mechanics [PDF]
, 1998 The purpose of the paper is to explore different aspects of the covariance of (mostly) non-relativistic quantum mechanics. First, doubts are expressed concerning the claim that gauge fields can be 'generated' by way of imposition of (local) gauge ...
Brown, Harvey R
core
Molecular Oncology, EarlyView.Detection of extrachromosomal circular DNA (eccDNA) in plasma samples from EGFR‐mutated non‐small cell lung cancer patients. Plasma was collected before and during treatment with the EGFR‐tyrosine kinase inhibitor osimertinib. Plasma eccDNA was detected in all cancer samples, and the presence of the EGFR gene on eccDNA serves as a potential biomarker ...
Simone Stensgaard +5 more
wiley +1 more source
On Solidarity: Gramsci’s Objectivity as a Corrective to Buber’s I-It
Phenomenology and Mind, 2017 I and Thou sets out a dichotomy of human interactions between the merely objective I-It and the intense intersubjective relationship of the I-Thou, creating a problem of how one is to differentiate the I-It relations that are healthy and natural, and ...
Ryan Adams
doaj +1 more source
Screening for lung cancer: A systematic review of overdiagnosis and its implications
Molecular Oncology, EarlyView.Low‐dose computed tomography (CT) screening for lung cancer may increase overdiagnosis compared to no screening, though the risk is likely low versus chest X‐ray. Our review of 8 trials (84 660 participants) shows added costs. Further research with strict adherence to modern nodule management strategies may help determine the extent to which ...
Fiorella Karina Fernández‐Sáenz +12 more
wiley +1 more source
Climate Change Journalism: From Agony to Agonistic Debate
Desenvolvimento e Meio Ambiente, 2017 Starting from a politicized outlook on climate change, this essay criticizes mainstream journalistic norms for failing to enable an agonistic, democratic debate about how to move forward.
Yves Pepermans, Pieter Maeseele
doaj +1 more source