Results 221 to 230 of about 522,390 (383)

Hyperpolarization Modulation of the T‐Type hCav3.2 Channel by Human Synenkephalin [1–53], a Shrew Neurotoxin Analogue without Paralytic Effects

open access: yesAngewandte Chemie, EarlyView.
Human synenkephalin [1–53] (hSYN), an analogue peptide of shrew saliva neurotoxins, was synthesized and its structural characteristics studied. Synthetic hSYN potently activated the T‐type voltage‐gated Ca channel hCav3.2 but did not paralyze mealworms. These findings offer new insight into neurological disorder treatment and evolutionary mechanisms of
Ryo Fukuoka   +5 more
wiley   +2 more sources

Effects of pregnancy on neuron electrophysiology in prefrontal cortex, hippocampus, and basolateral amygdala of mouse brain

open access: yesAnimal Models and Experimental Medicine, EarlyView.
The electrophysiological change in neurons might contribute to the cognitive and emotional changes during pregnancy. Abstract Background Pregnancy affects learning and memory in women. Thus, to investigate the effects of pregnancy, the authors examined the brain electrophysiology of pregnant mice.
Xuefan Bin, Huijuan Luo
wiley   +1 more source

Clean Cut (adaptive, multimodal surgical infection prevention programme) for low‐resource settings: a prospective quality improvement study

open access: yesBJS (British Journal of Surgery), EarlyView., 2020
Clean Cut is a multimodal, adaptive, checklist‐based infection prevention programme designed to improve compliance with six critical perioperative infection prevention practices. After introducing the programme at five hospitals in Ethiopia, compliance with critical infection prevention standards significantly improved and the relative risk of ...
J. A. Forrester   +16 more
wiley   +1 more source

Development of a single‐nucleotide polymorphism panel genotyping system for genetic analysis of Chinese hamsters

open access: yesAnimal Models and Experimental Medicine, EarlyView.
Here, we developed a novel Chinese hamster genetic quality detection system using single‐nucleotide polymorphism (SNP) markers following this process. To obtain SNP loci, we conducted whole genome sequencing on 24 Chinese hamsters. Then, we employed an SNP loci screening criterion that we set up previously and initially screened 214 SNP loci with wide ...
Minghe Sun   +14 more
wiley   +1 more source

Labelled OBS test bed for contention resolution study

open access: green, 2008
Thomas Legrand   +3 more
openalex   +2 more sources

Neuroimaging Predictors of Cognitive Resilience against Alzheimer's Disease Pathology

open access: yesAnnals of Neurology, Volume 97, Issue 6, Page 1038-1050, June 2025.
Objective Some individuals demonstrate greater cognitive resilience—the ability to maintain cognitive performance despite adverse brain‐related changes—through as yet unknown mechanisms. We examined whether cortical thickness in several brain regions confers resilience against cognitive decline in amyloid‐positive adults by moderating the effects of ...
McKenna E. Williams   +7 more
wiley   +1 more source

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