Impaired Autophagic Flux in Adipose Tissue Aggravates Pancreatic Injury in Obesity‐Related Severe Acute Pancreatitis [PDF]
Immunity, Inflammation and DiseaseBackground Adipose tissue (AT) playing a crucial role in obesity‐related pancreatitis. This study investigated the impact of autophagy in AT on pancreatic injury during obesity‐related severe acute pancreatitis (SAP).
Li‐Ping Sheng +6 more
doaj +2 more sources
The mitigation of activity-based anorexia by obese adipose tissue transplant is abolished by neonatal AgRP neuron ablation [PDF]
Translational PsychiatryAnorexia nervosa (AN) is an eating disorder observed primarily in girls and women, and is characterized by a low body weight, hypophagia, and hyperactivity.
Dongmin J. Yoon +7 more
doaj +2 more sources
Hormonal and enzymatic analysis for pancreas of diabetic and obese mice in Iraq [PDF]
Caspian Journal of Environmental Sciences, 2022 For our knowledge, this appears to be first Iraqi study aimed for detection the concentration of pancreatic exocrine enzymes and endocrine hormones as well as lipid profile in obese, diabetic as well as obese/diabetic mice.
Nasreen Habib Humaidan Al-Moussawi
doaj +1 more source
PLoS ONE, 2022 Background Non-alcoholic fatty liver disease (NAFLD) ranks first among liver diseases in Western countries. NAFLD is typically associated with obesity and diabetes, however it also develops in lean individuals without metabolic syndrome.
Emma Hymel +3 more
doaj +2 more sources
Obesity Alters cytokine signaling and gut microbiome in septic mice
Innate Immunity, 2023 Sepsis is a leading cause of mortality. Plasma cytokine levels may identify those at increased risk of mortality from sepsis. Our aim was to understand how obesity alters cytokine levels during early sepsis and its correlation with survival. Six-week-old
Lauren Bodilly +5 more
doaj +1 more source
Cell Death Discovery, 2023 Obese people with acute pancreatitis (AP) have an increased risk of developing severe acute pancreatitis (SAP), which prolongs the length of hospital stay and increases mortality.
Kunlei Wang +10 more
doaj +1 more source
Activating brown adipose tissue for weight loss and lowering of blood glucose levels: a microPET study using obese and diabetic model mice. [PDF]
PLoS ONE, 2014 PURPOSE: This study aims at using 18F-FDG microPET to monitor the brown adipose tissue (BAT) glucose metabolism in obese and diabetic mouse models under different interventions, and study the therapeutic potential of BAT activation for weight loss and ...
Chenxi Wu +8 more
doaj +1 more source
Exercise Improves Host Response to Influenza Viral Infection in Obese and Non-Obese Mice through Different Mechanisms. [PDF]
PLoS ONE, 2015 Obesity has been associated with greater severity of influenza virus infection and impaired host defense. Exercise may confer health benefits even when weight loss is not achieved, but it has not been determined if regular exercise improves immune ...
Kristi J Warren +7 more
doaj +1 more source
Expression of peroxisome proliferator-activated receptor (PPAR)-α and PPAR-γ in the lung tissue of obese mice and the effect of rosiglitazone on proinflammatory cytokine expressions in the lung tissue [PDF]
Korean Journal of Pediatrics, 2013 PurposeWe investigated the mRNA levels of peroxisome proliferator-activated receptor (PPAR)-α, PPAR-γ, adipokines, and cytokines in the lung tissue of lean and obese mice with and without ovalbumin (OVA) challenge, and the effect of rosiglitazone, a PPAR-
Seung Lok Ryu +8 more
doaj +1 more source
Dectin-1 Activation Exacerbates Obesity and Insulin Resistance in the Absence of MyD88 [PDF]
, 2017 This work was supported by Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP, grant numbers 11/15682-4, 12/02270-2, 15/18121-4), Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq, Regenera INCT Process Grant 465656/2014-5 ...
Aguiar, Cristhiane Favero +25 more
core +8 more sources