Activating brown adipose tissue for weight loss and lowering of blood glucose levels: a microPET study using obese and diabetic model mice. [PDF]
PLoS ONE, 2014 PURPOSE: This study aims at using 18F-FDG microPET to monitor the brown adipose tissue (BAT) glucose metabolism in obese and diabetic mouse models under different interventions, and study the therapeutic potential of BAT activation for weight loss and ...
Chenxi Wu +8 more
doaj +1 more source
Expression of peroxisome proliferator-activated receptor (PPAR)-α and PPAR-γ in the lung tissue of obese mice and the effect of rosiglitazone on proinflammatory cytokine expressions in the lung tissue [PDF]
Korean Journal of Pediatrics, 2013 PurposeWe investigated the mRNA levels of peroxisome proliferator-activated receptor (PPAR)-α, PPAR-γ, adipokines, and cytokines in the lung tissue of lean and obese mice with and without ovalbumin (OVA) challenge, and the effect of rosiglitazone, a PPAR-
Seung Lok Ryu +8 more
doaj +1 more source
Adipsin expression in lean and obese transgenic mice.
, 1992 Adipsin expression in lean and obese transgenic ...
Kenneth Andrew. Platt (7995476)
core +5 more sources
Metabolic effects of CCL5 deficiency in lean and obese mice
Frontiers in Immunology, 2023 Accumulation and activation of immunocytes in adipose tissues are essential to obesity-induced inflammation and insulin resistance. Chemokines are pivotal for the recruitment of immunocytes in adipose tissue during obesity. Chemokine (C-C motif) ligand 5
Hui Zhou +22 more
doaj +1 more source
Metformin attenuates the exacerbation of the allergic eosinophilic inflammation in high fat-diet-induced obesity in mice. [PDF]
PLoS ONE, 2013 A positive relationship between obesity and asthma has been well documented. The AMP-activated protein kinase (AMPK) activator metformin reverses obesity-associated insulin resistance (IR) and inhibits different types of inflammatory responses.
Marina Ciarallo Calixto +9 more
doaj +1 more source
Malaria and obesity: obese mice are resistant to cerebral malaria [PDF]
Malaria Journal, 2008 The relationship between malaria and obesity are largely unknown. This is partly due to the fact that malaria occurs mainly in tropical areas where, until recently, obesity was not prevalent. It now appears, however, that obesity is emerging as a problem in developing countries.
Robert, Vincent +5 more
openaire +4 more sources
Journal of Cachexia, Sarcopenia and Muscle, 2022 Background Muscle weakness is a frequently occurring complication of sepsis, associated with increased morbidity and mortality. Interestingly, obesity attenuates sepsis‐induced muscle wasting and weakness.
Wouter Vankrunkelsven +8 more
doaj +1 more source
Wound healing in mice with high-fat diet- or ob gene-induced diabetes-obesity syndromes : a comparative study [PDF]
, 2010 In the past, the genetically diabetic-obese diabetes/diabetes (db/db) and obese/obese (ob/ob) mouse strains were used to investigate mechanisms of diabetes-impaired wound healing.
Stefan Frank +13 more
core +1 more source
Alterations in oral [1-(14)C] 18:1n-9 distribution in lean wild-type and genetically obese (ob/ob) mice. [PDF]
PLoS ONE, 2015 Obesity may result from altered fatty acid (FA) disposal. Altered FA distribution in obese individuals is poorly understood. Lean wild-type C57BL/6J and obese C57BL/6Job/ob mice received an oral dose of [1-(14)C]18:1n-9 (oleic acid), and the ...
Xinxia Wang +4 more
doaj +1 more source
Gad65 is recognized by t-cells, but not by antibodies from nod-mice [PDF]
, 1994 Since the 64kDa-protein glutamic acid decarboxylase (GAD) is one of the major autoantigens in T-cell mediated Type 1 diabetes, its relevance as a T-cell antigen needs to be clarified. After isolation of splenic T-cells from non-obese diabetic (NOD) mice,
Seißler, Jochen +4 more
core +1 more source