Results 61 to 70 of about 747,238 (298)

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Movement Notation Revisited: Syntax of the Common Morphokinetic Alphabet (CMA) System

open access: yesFrontiers in Psychology, 2018
Advances in the study of non-verbal behavior and communication have generated a need for movement transcription systems capable of incorporating continuous developments in visual and computer technology.
Conrad Izquierdo, M. Teresa Anguera
doaj   +1 more source

Diachronic analysis application for the detection of soccer performance standards: a case study

open access: yesInternational Journal of Computer Science in Sport, 2020
The purpose of this study is to analyse the interactions established by Gerard Piqué, one of the world’s top defenders, within the general context of the team.
Maneiro R, Amatria M, Anguera MT
doaj   +1 more source

Observing Neurodiversity, Observing Methodology: Ethnography in Pandemic Times

open access: yesInternational Journal of Qualitative Methods
Ethnographic researchers have long relied upon observation as a powerful means to learn about social relations. This paper discusses research observation that was conducted as a part of an institutional ethnography (IE) investigating how people use the language and ideas of neurodiversity across different settings.
Margaret F. Gibson   +5 more
openaire   +2 more sources

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

open access: yesFEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai   +9 more
wiley   +1 more source

Stability of behaviour patterns in the 200m breaststroke

open access: yesRevista Brasileira de Cineantropometria e Desempenho Humano, 2016
The aim of this study was to analyse the stability of the breaststroke technique in five elite swimmers in a 200m event using a qualitative analysis. The codification of the behaviour of each swimmer during the execution of 20 cycles was achieved using ...
Hugo Louro   +4 more
doaj   +1 more source

Guidelines for reporting evaluations based on observational methodology [PDF]

open access: yes, 2015
Background: Observational methodology is one of the most suitable research designs for evaluating fi delity of implementation, especially in complex interventions.
Anguera Argilaga, María Teresa   +3 more
core  

The planar cell polarity protein Vangl2 interacts with the PDZ‐domains of Scribble but not with a unique PDZ‐like domain in Inturned

open access: yesFEBS Letters, EarlyView.
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes   +4 more
wiley   +1 more source

Analysis of the effectiveness of corner kicks in the Brazilian Football Championship 2023

open access: yesHuman Movement
Purpose The aim of the present study was to identify and examine the effectiveness of the most frequent execution patterns of corner kick strategies used in the First Division of the Brazilian Football Championship during the 2023 season.
Guilherme De Oliveira Santos Silva   +4 more
doaj   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

open access: yesFEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa   +5 more
wiley   +1 more source

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