Results 81 to 90 of about 343,769 (301)

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

FEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa, Shinya Sugimoto, Toshiro Sato   +2 more
wiley   +1 more source

Analysis of the Influence of the Numerical Relation in Handball During an Organized Attack, Specifically the Tactical Behavior of the Center Back

Frontiers in Psychology, 2019
In the last decades, observational methodology has been widely used in scientific research in sport, namely in the study of team games like handball, due to its characteristics.
João Nunes Prudente, João Nunes Prudente, Américo Ramos Cardoso, Ana Jose Rodrigues, Duarte Filipe Sousa   +4 more
doaj   +1 more source

Design and analysis strategies for robust microbiome ageing research

FEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik, İsmail Güderer, Yi Wang, Tayyaba Alvi, Prasoon Pandey, Handan Melike Dönertaş   +5 more
wiley   +1 more source

Evolution of attack in handball when playing 7 vs. 6 with empty goal between 2020 and 2023: coaches’ perception vs. observational results

Frontiers in Sports and Active Living
IntroductionRecently, several studies on the 7 vs. 6 “empty goal” (EG) in handball have produced different and even contradictory results. The aim of the present study was to investigate the behavior of teams and players in the 7 vs.
João Nunes Prudente, João Nunes Prudente, Américo Ramos Cardoso, Ana José Rodrigues, Ana José Rodrigues, Ana José Rodrigues, João N. Mendes, Catarina Fernando, Catarina Fernando, Helder Lopes, Helder Lopes, Alejandro Trejo-Silva, Alejandro Trejo-Silva, Duarte Filipe Sousa   +13 more
doaj   +1 more source

Testing the acceptability and feasibility of video observational methodology to measure parent-adolescent communication and interaction. [PDF]

Front Child Adolesc Psychiatry, 2023
Lekhuleni F, Desai R, Coetzee B, Pearson R, Rochat TJ.   +4 more
europepmc   +1 more source

The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers

Molecular Oncology, EarlyView.
The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce, Simone Bini, Marialuisa Sponziello, Giorgio Grani, Giulia Fiscon, Paola Paci, Lorenzo Farina, Rosa Falcone, Valentina Maggisano, Sebastiano Filetti, Cosimo Durante, Antonella Verrienti   +11 more
wiley   +1 more source

Methodology of Observational Cosmology

, 2002
These lectures focus on the methods of observational cosmology and their physical basis. After a brief reminder of the essential elements of the Big Bang model, we look at some of the basic methods for surveying the homogeneous universe.
Bartlett, J.G.
core   +1 more source

Analysis of the use, effectiveness, and efficiency of the pick and roll in elite women’s basketball

Frontiers in Sports and Active Living
This study investigates the effectiveness and outcomes of “pick and roll” plays in elite women's basketball, focusing on the 2021-2022 EuroLeague Final Four.
M. Amatria, I. Iván-Baragaño, J. L. Losada, R. Maneiro   +3 more
doaj   +1 more source

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

Molecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat, Aslihan Kucuk, Omer Erdogan, Samed Ozer, Bensu Kozan, Tugba Cuceli, Erkan Gumus, Evrim Cevik, Ozge Cevik   +8 more
wiley   +1 more source

Estimating propensity scores with missing covariate data using general location mixture models

, 2009
In many observational studies, researchers estimate causal effects using propensity scores, e.g., by matching or sub-classifying on the scores. Estimation of propensity scores is complicated when some values of the covariates aremissing.
Reiter, Jerome P., Jerome P. Reiter, Mitra, Robin, Robin Mitra   +3 more
core   +1 more source