Results 81 to 90 of about 4,109,796 (295)

On the generation of data in the study of social interaction

open access: yesPsicologia: Teoria e Pesquisa
In this article, it is argued that the most urgent and necessary requisite for observational research is the creation of material-sensitive categories which depict details of specific situational and human conditions of exchange.
Kurt Kreppner
doaj   +1 more source

Offensive Transitions in High-Performance Football: Differences Between UEFA Euro 2008 and UEFA Euro 2016

open access: yesFrontiers in Psychology, 2019
Coaches, footballers and researchers agree that offensive transitions are one of the most important moments in football today. In a sport where defense over attack dominates, with low scores on the scoreboard, the importance of these actions from the ...
Rubén Maneiro   +6 more
doaj   +1 more source

Identification of a Shiga toxin A‐derived peptide internalized into Gb3 receptor‐bearing cells via interaction with the Shiga toxin B subunit

open access: yesFEBS Letters, EarlyView.
The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi   +6 more
wiley   +1 more source

Analysis of the Influence of the Numerical Relation in Handball During an Organized Attack, Specifically the Tactical Behavior of the Center Back

open access: yesFrontiers in Psychology, 2019
In the last decades, observational methodology has been widely used in scientific research in sport, namely in the study of team games like handball, due to its characteristics.
João Nunes Prudente   +4 more
doaj   +1 more source

Investigating transcription factor dynamics in health and disease using FRAP

open access: yesFEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj   +3 more
wiley   +1 more source

From observational to dynamic genetics [PDF]

open access: yes, 2014
Twin and family studies have shown that most traits are at least moderately heritable. But what are the implications of finding genetic influence for the design of intervention and prevention programs?
Oliver S. P. Davis   +7 more
core   +1 more source

An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes

open access: yesFEBS Letters, EarlyView.
GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg   +14 more
wiley   +1 more source

Methodology for Observation of House Types

open access: yesAnnals of The Tohoku Geographycal Asocciation, 1972
In order to undertstand aspects of houses in today's settlement it is important to be able to observe house types speedily and extensively. One method is to utilize the automobile. Using a pre-determined classification scheme, two observers may rapidly relay the data to a third person for recording.
openaire   +2 more sources

Nutrient/TOR signaling controls adipose mitochondrial transcription factor A (TFAM) to regulate organismal growth in Drosophila

open access: yesFEBS Letters, EarlyView.
Animals must match their growth rate to available nutrients. We show that in Drosophila larvae, the nutrient‐sensing TOR kinase controls growth by regulating levels of TFAM, a key regulator of mitochondrial function, in the adipose tissue. When nutrients are abundant, high TOR activity suppresses TFAM, lowering mitochondrial bioenergetic activity and ...
Shrivani Sriskanthadevan‐Pirahas   +4 more
wiley   +1 more source

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