Results 81 to 90 of about 740,500 (344)

Adenosine‐to‐inosine editing of miR‐200b‐3p is associated with the progression of high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
A‐to‐I editing of miRNAs, particularly miR‐200b‐3p, contributes to HGSOC progression by enhancing cancer cell proliferation, migration and 3D growth. The edited form is linked to poorer patient survival and the identification of novel molecular targets.
Magdalena Niemira   +14 more
wiley   +1 more source

Design, Validation, and Reliability of an Observational Instrument for Technical and Tactical Actions in Singles Badminton

open access: yesFrontiers in Psychology, 2020
Technical and tactical actions are decisive in terms of badminton player competitive performance. The main objective of this research was to design, validate, and estimate the reliability of an observational instrument for the analysis of the tactical ...
Gema Torres-Luque   +7 more
doaj   +1 more source

Karl Popper's Philosophical Breakthrough [PDF]

open access: yes, 2004
Despite his well-known deductivism, in his early (unpublished) writings, Popper held an inductivist position. Up to 1929 epistemology entered Popper's reflections only as far as the problem was that of the justification of the scientific character of ...
Gattei, Stefano
core   +1 more source

Investigating the cell of origin and novel molecular targets in Merkel cell carcinoma: a historic misnomer

open access: yesMolecular Oncology, EarlyView.
This study indicates that Merkel cell carcinoma (MCC) does not originate from Merkel cells, and identifies gene, protein & cellular expression of immune‐linked and neuroendocrine markers in primary and metastatic Merkel cell carcinoma (MCC) tumor samples, linked to Merkel cell polyomavirus (MCPyV) status, with enrichment of B‐cell and other immune cell
Richie Jeremian   +10 more
wiley   +1 more source

On the generation of data in the study of social interaction

open access: yesPsicologia: Teoria e Pesquisa
In this article, it is argued that the most urgent and necessary requisite for observational research is the creation of material-sensitive categories which depict details of specific situational and human conditions of exchange.
Kurt Kreppner
doaj   +1 more source

Emerging role of ARHGAP29 in melanoma cell phenotype switching

open access: yesMolecular Oncology, EarlyView.
This study gives first insights into the role of ARHGAP29 in malignant melanoma. ARHGAP29 was revealed to be connected to tumor cell plasticity, promoting a mesenchymal‐like, invasive phenotype and driving tumor progression. Further, it modulates cell spreading by influencing RhoA/ROCK signaling and affects SMAD2 activity. Rho GTPase‐activating protein
Beatrice Charlotte Tröster   +3 more
wiley   +1 more source

Offensive Transitions in High-Performance Football: Differences Between UEFA Euro 2008 and UEFA Euro 2016

open access: yesFrontiers in Psychology, 2019
Coaches, footballers and researchers agree that offensive transitions are one of the most important moments in football today. In a sport where defense over attack dominates, with low scores on the scoreboard, the importance of these actions from the ...
Rubén Maneiro   +6 more
doaj   +1 more source

On the history and use of some standard statistical models

open access: yes, 2008
This paper tries to tell the story of the general linear model, which saw the light of day 200 years ago, and the assumptions underlying it. We distinguish three principal stages (ignoring earlier more isolated instances). The model was first proposed in
Lehmann, E. L.
core   +1 more source

PYCR1 inhibition in bone marrow stromal cells enhances bortezomib sensitivity in multiple myeloma cells by altering their metabolism

open access: yesMolecular Oncology, EarlyView.
This study investigated how PYCR1 inhibition in bone marrow stromal cells (BMSCs) indirectly affects multiple myeloma (MM) cell metabolism and viability. Culturing MM cells in conditioned medium from PYCR1‐silenced BMSCs impaired oxidative phosphorylation and increased sensitivity to bortezomib.
Inge Oudaert   +13 more
wiley   +1 more source

Evolution of attack in handball when playing 7 vs. 6 with empty goal between 2020 and 2023: coaches’ perception vs. observational results

open access: yesFrontiers in Sports and Active Living
IntroductionRecently, several studies on the 7 vs. 6 “empty goal” (EG) in handball have produced different and even contradictory results. The aim of the present study was to investigate the behavior of teams and players in the 7 vs.
João Nunes Prudente   +13 more
doaj   +1 more source

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